2022
Frequency and Geographic Distribution of Borrelia miyamotoi, Borrelia burgdorferi, and Babesia microti Infections in New England Residents.
Johnston D, Kelly JR, Ledizet M, Lavoie N, Smith RP, Parsonnet J, Schwab J, Stratidis J, Espich S, Lee G, Maciejewski KR, Deng Y, Majam V, Zheng H, Bonkoungou SN, Stevens J, Kumar S, Krause PJ. Frequency and Geographic Distribution of Borrelia miyamotoi, Borrelia burgdorferi, and Babesia microti Infections in New England Residents. Clinical Infectious Diseases 2022 PMID: 35325084, DOI: 10.1093/cid/ciac107.Peer-Reviewed Original ResearchBabesia microti infectionB. miyamotoiMicroti infectionB. burgdorferiB. microtiAcute undifferentiated febrile illnessCross-sectional seroprevalence studyBorrelia miyamotoiUndifferentiated febrile illnessB. miyamotoi infectionBorrelia burgdorferiLevel of seroprevalenceIxodes scapularis ticksFebrile illnessTickborne infectionMiyamotoi infectionSeroprevalence studyHuman infectionsIxodes pacificus ticksClinical casesInfectionSerum samplesAverage seroprevalenceSpecific antibodiesScapularis ticks
2021
Babesiosis
Chen T, Mamoun C, Krause P. Babesiosis. 2021, 1298-1304. DOI: 10.1093/med/9780190888367.003.0200.Peer-Reviewed Original ResearchB. microtiHard-bodied ticksHuman granulocytic anaplasmosisPowassan virusEtiologic agentIntraerythrocytic protozoaLyme diseaseBorrelia miyamotoiGranulocytic anaplasmosisBabesia infectionBorrelia burgdorferiDiseaseZoonotic diseaseB. duncaniAnaplasma phagocytophilumApicomplexa phylumInfectionMicrotiB. venatorumB. divergensBabesia sppBabesiosisIxodes scapularisPrimary vectorFever
2020
644. Borrelia miyamotoi and Borrelia burgdorferi Seroprevalence in New England
Johnston D, Kelly J, Ledizet M, Lavoie N, Krause P. 644. Borrelia miyamotoi and Borrelia burgdorferi Seroprevalence in New England. Open Forum Infectious Diseases 2020, 7: s381-s381. PMCID: PMC7777872, DOI: 10.1093/ofid/ofaa439.838.Peer-Reviewed Original ResearchSerum samplesB. burgdorferi antibodiesMethods Serum samplesNon-endemic areasResidential zip codeResidential countyBackground diseasesBurgdorferi antibodiesMultiplex LuminexStudy participantsLyme diseaseSpirochetal pathogensBorrelia miyamotoiB. miyamotoiBorrelia burgdorferiB. burgdorferiCausative agentZip codesHuman exposureDiseaseAntibodiesMiyamotoiBurgdorferiIxodes scapularisBorrelia burgdorferi and Borrelia miyamotoi seroprevalence in California blood donors
Brummitt SI, Kjemtrup AM, Harvey DJ, Petersen JM, Sexton C, Replogle A, Packham AE, Bloch EM, Barbour AG, Krause PJ, Green V, Smith WA. Borrelia burgdorferi and Borrelia miyamotoi seroprevalence in California blood donors. PLOS ONE 2020, 15: e0243950. PMID: 33370341, PMCID: PMC7769429, DOI: 10.1371/journal.pone.0243950.Peer-Reviewed Original ResearchConceptsLyme diseaseBlood donorsB. miyamotoiB. burgdorferiEndemic countiesWestern blotBorrelia miyamotoiB. burgdorferi antibodiesAdult blood donorsBorrelia burgdorferiIgG Western blotBlood donor seraRisk of infectionELISA test systemBurgdorferi antibodiesDonor seraC6 ELISAClinical casesEquivocal samplesHuman casesDiseaseAntibodiesI. pacificus ticksMiyamotoiBurgdorferi
2017
Human seroprevalence of Borrelia miyamotoi in Manitoba, Canada, in 2011-2014: a cross-sectional study
Kadkhoda K, Dumouchel C, Brancato J, Gretchen A, Krause PJ. Human seroprevalence of Borrelia miyamotoi in Manitoba, Canada, in 2011-2014: a cross-sectional study. CMAJ Open 2017, 5: e690-e693. PMID: 28882852, PMCID: PMC5621960, DOI: 10.9778/cmajo.20170070.Peer-Reviewed Original ResearchEnzyme-linked immunosorbent assayWestern blotLyme diseasePeptide enzyme-linked immunosorbent assayCross-sectional studyResidents of ManitobaTick-borne relapsing feverHuman seroprevalenceResidents of areasResidual seraRelapsing feverImmunosorbent assayBorrelia miyamotoiInitial reportSerumFeverInfectionDiseaseAntibodiesBlotBorreliaParticipantsSeronegativeSeropositiveHumans
2016
Hard Tick Relapsing Fever Caused by Borrelia miyamotoi in a Child
Krause P, Schwab J, Narasimhan S, Brancato J, Xu G, Rich SM. Hard Tick Relapsing Fever Caused by Borrelia miyamotoi in a Child. The Pediatric Infectious Disease Journal 2016, 35: 1352-1354. PMID: 27626914, PMCID: PMC5106309, DOI: 10.1097/inf.0000000000001330.Peer-Reviewed Original Research
2015
Borrelia miyamotoi infection in nature and in humans
Krause PJ, Fish D, Narasimhan S, Barbour AG. Borrelia miyamotoi infection in nature and in humans. Clinical Microbiology And Infection 2015, 21: 631-639. PMID: 25700888, PMCID: PMC4470780, DOI: 10.1016/j.cmi.2015.02.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsB. miyamotoi infectionMiyamotoi infectionClinical manifestationsB. miyamotoiLyme diseaseBorrelia miyamotoi infectionAcute febrile illnessCommon clinical manifestationsBlood smear examinationPublic health importanceHuman granulocytic anaplasmosisFever group spirochetesFebrile illnessAntibiotic therapyDisease groupEtiologic diagnosisSevere diseaseSmear examinationIxodes persulcatus ticksHealth importanceInfectionHuman casesGranulocytic anaplasmosisBorrelia miyamotoiDisease
2014
Blood transfusion transmission of the tick‐borne relapsing fever spirochete Borrelia miyamotoi in mice
Krause PJ, Hendrickson JE, Steeves TK, Fish D. Blood transfusion transmission of the tick‐borne relapsing fever spirochete Borrelia miyamotoi in mice. Transfusion 2014, 55: 593-597. PMID: 25251880, DOI: 10.1111/trf.12879.Peer-Reviewed Original ResearchConceptsTransfusion transmissionRed blood cellsBorrelia miyamotoiBlood transfusion transmissionMurine transfusion modelFever spirochete Borrelia miyamotoiSpirochete clearanceRecipient bloodC57BL/6 miceMouse recipientsTransfusion modelMouse modelTransfusionMurine bloodHuman infectionsWet mountLyme diseaseStudy designBlood cellsMiceMiyamotoiSpirochetemiaFever spirochetesBloodBodied ticks
2013
Human Borrelia miyamotoi Infection in the United States
Krause PJ, Narasimhan S, Wormser GP, Rollend L, Fikrig E, Lepore T, Barbour A, Fish D. Human Borrelia miyamotoi Infection in the United States. New England Journal Of Medicine 2013, 368: 291-293. PMID: 23323920, PMCID: PMC3934646, DOI: 10.1056/nejmc1215469.Peer-Reviewed Original Research
2011
Humans Infected with Relapsing Fever Spirochete Borrelia miyamotoi, Russia - Volume 17, Number 10—October 2011 - Emerging Infectious Diseases journal - CDC
Platonov AE, Karan LS, Kolyasnikova NM, Makhneva NA, Toporkova MG, Maleev VV, Fish D, Krause PJ. Humans Infected with Relapsing Fever Spirochete Borrelia miyamotoi, Russia - Volume 17, Number 10—October 2011 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2011, 17: 1816-1823. PMID: 22000350, PMCID: PMC3310649, DOI: 10.3201/eid1710.101474.Peer-Reviewed Original ResearchConceptsB. miyamotoi infectionMiyamotoi infectionInfectious Diseases journal - CDCBorrelia miyamotoiInfluenza-like illnessB. burgdorferi infectionFever spirochete Borrelia miyamotoiDisease-like symptomsFebrile illnessI. ricinus ticksErythema migransClinical manifestationsIxodid tick vectorsBurgdorferi infectionI. scapularis ticksIxodes persulcatus ticksInfectionRicinus ticksScapularis ticksB. burgdorferiB. gariniiFeverWidespread prevalenceIllnessMiyamotoi