2024
A meta-analysis highlights the idiosyncratic nature of tradeoffs in laboratory models of virus evolution
Kabengele K, Turner W, Turner P, Ogbunugafor C. A meta-analysis highlights the idiosyncratic nature of tradeoffs in laboratory models of virus evolution. Virus Evolution 2024, 10: veae105. PMID: 39717708, PMCID: PMC11665823, DOI: 10.1093/ve/veae105.Peer-Reviewed Original ResearchEvolutionary Invasion Analysis of Modern Epidemics Highlights the Context-Dependence of Virulence Evolution
Surasinghe S, Kabengele K, Turner P, Ogbunugafor C. Evolutionary Invasion Analysis of Modern Epidemics Highlights the Context-Dependence of Virulence Evolution. Bulletin Of Mathematical Biology 2024, 86: 88. PMID: 38877355, PMCID: PMC11178639, DOI: 10.1007/s11538-024-01313-0.Peer-Reviewed Original Research
2009
Predicting Virus Evolution: The Relationship between Genetic Robustness and Evolvability of Thermotolerance
Ogbunugafor CB, McBride RC, Turner PE. Predicting Virus Evolution: The Relationship between Genetic Robustness and Evolvability of Thermotolerance. Cold Spring Harbor Symposia On Quantitative Biology 2009, 74: 109-118. PMID: 19843592, DOI: 10.1101/sqb.2009.74.023.Peer-Reviewed Original ResearchConceptsGenetic robustnessVirus evolvabilityMutational inputExtant populationsEvolutionary biologistsEvolutionary eventsExperimental evolutionEvolutionary biologyVirus adaptabilityPhylogenetic methodsAdaptive thermotoleranceVirus evolutionEvolutionary processesHost populationsEvolvabilityPredictive scienceThermotoleranceNew environmentHistorical patternsMicrobesEvolutionBiologistsOrganismsBiologyCanalization
2008
Robustness promotes evolvability of thermotolerance in an RNA virus
McBride RC, Ogbunugafor CB, Turner PE. Robustness promotes evolvability of thermotolerance in an RNA virus. BMC Ecology And Evolution 2008, 8: 231. PMID: 18694497, PMCID: PMC2518931, DOI: 10.1186/1471-2148-8-231.Peer-Reviewed Original ResearchConceptsGenetic robustnessEfficacy of selectionNew habitatsEvolutionary biologyVirus adaptabilityLaboratory populationsMutational changesNew nichesEvolvabilityRNA virusesFace of perturbationsGreater toleranceThermotoleranceRobust clonesNovel environmentClonesBiological systemsBalance of robustnessFuture adaptationUnderlying mechanismHabitatsNicheBiologyGreater resistancePopulation
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