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Pamela Valentino, MD, MSc

Assistant Professor of Pediatrics (Gastroenterology)

Contact Information

Pamela Valentino, MD, MSc

Patient Care Locations

Mailing Address

  • Pediatric Gastroenterology & Hepatology

    Yale School of Medicine, PO Box 208064

    New Haven, CT 06520-8064

    United States



Pamela Valentino, MD, MSc is an Assistant Professor of Pediatrics and a Transplant Hepatologist at Yale University School of Medicine. Dr. Valentino trained in Gastroenterology and Hepatology at the Hospital for Sick Children in Toronto, Canada, and she completed sub-specialty training in Advanced Pediatric Transplant Hepatology at the Boston Children’s Hospital, in Boston, Massachusetts. At these centers of excellence in pediatrics, she has cared for infants and children with a spectrum of liver diseases and recipients of liver transplants.

Dr. Valentino's research interests focus on conditions that cause bile duct injury and can threaten liver function. Primary sclerosing cholangitis is an autoimmune disease of the bile ducts, and she has collaborated with centers from around the world to describe this disease in children, identify ways to evaluate the severity of the illness, and work on clinical trials.

Post-liver transplant, bile duct strictures occur in approximately 5% of children. She is investigating biliary stricture management via multicenter collaborations through the Society of Pediatric Liver Transplantation (SPLIT) to identify effective strategies to reduce repeated interventions and maximize transplant graft and patient health.

Outside of biliary disease, she examines OPTN/UNOS national transplant data to investigate strategies associated with increased organ donor utilization to minimize pediatric death and worsening illness while on the liver transplant waitlist.

Dr. Valentino is also collaborating with Dr. Michael Schilsky at Yale University on the Wilson Disease (WD) Registry at WD Centers of Excellence to learn more about the spectrum of disease in patients with WD from infancy to adulthood.

Dr. Valentino is collaborating with Dr. Binita Kamath at the Hospital for Sick Children and University of Toronto on an international study of Alagille syndrome called the Global ALagille Alliance (GALA). We hope to better understand Alagille Syndrome in children and advance management strategies.

Dr. Valentino is the site principal investigator at Yale for the International Registry of Congenital Porto-Systemic Shunts (IRCPSS). This group, led by Dr. Valérie McLin, is studying vascular shunts of the liver to better identify patients who are at risk for developing complications and to offer them standardized care.

Education & Training

  • Transplant Hepatology Fellowship
    Boston Children’s Hospital, Harvard Medical School, Boston, MA (2015)
  • GI Fellowship
    The Hospital for Sick Children, University of Toronto, Toronto, ON (2014)
  • MSc
    University of Toronto, Clinical Epidemiology and Health Care Research (2014)
  • Pediatrics Residency
    Montreal Children’s Hospital, McGill University, Montreal, QC (2010)
  • MD
    McGill University (2007)

Honors & Recognition

AwardAwarding OrganizationDate
Early Career Investigator Award in Clinical/Translational ScienceAmerican Association for the Study of Liver Diseases2018
2014-2015 CASL/Merck Clinical Hepatology Fellowship AwardCanadian Association for the Study of Liver Diseases2014
Dick Hamilton AwardHospital for Sick Children2014
Exceptional Trainee AwardHospital for Sick Children (SickKids) Research Institute2014
CAG/Shire Resident Research Training AwardCanadian Association of Gastroenterology2012

Professional Service

American Society of Transplantation, Liver and Intestine Community of PracticeExecutive Committee, Early Career Member-At-Large2020 - Present
American Society of Transplantation, Liver and Intestine Community of PracticeChair of Pediatric Subcommittee2020 - Present
The Transplantation SocietyMember2019 - Present
Society of Pediatric Liver Transplantation (SPLIT)Physician Chair of the Registry Operations Committee2018 - Present
American Society of Transplantation2015 - Present
Society of Pediatric Liver TransplantationMember2015 - Present
Royal College of Physicians and Surgeons of Canada2011 - Present
American Association for the Study of Liver Diseases2011 - Present
North American Society for Pediatric Gastroenterology, Hepatology and Nutrition2010 - Present

Departments & Organizations