Mediation Analysis of Acute Carotid Stenting in Tandem Lesions
Rodriguez Calienes A, Galecio-Castillo M, Petersen N, Ribo M, Farooqui M, Hassan A, Jumaa M, Divani A, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Lu Y, Vivanco-Suarez J, Dibas M, Mokin M, Yavagal D, Jovin T, Ortega-Gutierrez S. Mediation Analysis of Acute Carotid Stenting in Tandem Lesions. Neurology 2024, 103: e209617. PMID: 38959444, DOI: 10.1212/wnl.0000000000209617.Peer-Reviewed Original ResearchConceptsAcute carotid artery stentingCarotid artery stentingEndovascular therapyNon-CA groupFunctional outcomesTandem lesionsAnterior circulation tandem lesionsTreated with endovascular therapyMulticenter retrospective cohort studyCarotid artery stenting groupAssociated with better functional outcomesFavorable functional outcomeAcute carotid stentingRetrospective cohort studyAssociated with functional outcomePredictor of functional outcomeCervical lesionsMedian ageModified ThrombolysisReperfusion rateCohort studyPathophysiological mechanismsArtery stentingCarotid stentingReperfusionCervical Dissection in Patients With Tandem Lesions Is Associated With Distal Embolism and Lower Recanalization Success
Galecio-Castillo M, Guerrero W, Hassan A, Farooqui M, Jumaa M, Divani A, Abraham M, Petersen N, Fifi J, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Olivé-Gadea M, Tekle W, Zaidi S, Sabbagh S, Barkley T, Prasad A, De Leacy R, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Turabova C, Rodriguez-Calienes A, Dibas M, Mokin M, Yavagal D, Ribo M, Jovin T, Ortega-Gutierrez S. Cervical Dissection in Patients With Tandem Lesions Is Associated With Distal Embolism and Lower Recanalization Success. Stroke 2024, 55: 1808-1817. PMID: 38913799, DOI: 10.1161/strokeaha.123.046148.Peer-Reviewed Original ResearchConceptsInternal carotid arteryCervical internal carotid arteryDistal embolizationModified ThrombolysisTandem lesionsMulticenter retrospective cohort studyParenchymal hematoma type 2Internal carotid artery stenosis/occlusionModified Rankin Scale scoreSymptomatic intracranial hemorrhageInverse probability of treatment weightingCerebral Infarction scoreCervical ICA dissectionRetrospective cohort studyProbability of treatment weightingRankin Scale scoreAssociated with higher ratesFunctional independenceRates of hypertensionAssociated with distal embolizationSelf-expanding stentsDissection etiologyRisk of distal embolizationICA occlusionCervical dissection
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