2025
Different Responses to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage
Clocchiatti-Tuozzo S, Rivier C, Qureshi A, Renedo D, Huo S, Matouk C, Petersen N, de Havenon A, Sheth K, Rabinstein A, Falcone G, Hawkes M. Different Responses to Blood Pressure Reduction in Lobar and Deep Intracerebral Hemorrhage. Neurocritical Care 2025, 1-9. PMID: 40293696, DOI: 10.1007/s12028-025-02269-2.Peer-Reviewed Original ResearchRenal adverse eventsDeep intracerebral hemorrhageIntensive BP reductionRisk of renal adverse eventsRisk of HEHematoma expansionBP reductionATACH-2Intracerebral hemorrhageLobar intracerebral hemorrhageFunctional outcomesAntihypertensive Treatment of Acute Cerebral Hemorrhage IIAcute spontaneous intracerebral hemorrhageAcute intracerebral hemorrhageSpontaneous intracerebral hemorrhageAssociated with reduced riskUnfavorable functional outcomeBlood pressure reductionRandomized clinical trialsMultivariate logistic regression resultsPost hoc analysisAntihypertensive treatmentAdverse eventsClinical trialsIncreased risk
2024
Mediation Analysis of Acute Carotid Stenting in Tandem Lesions
Rodriguez Calienes A, Galecio-Castillo M, Petersen N, Ribo M, Farooqui M, Hassan A, Jumaa M, Divani A, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Lu Y, Vivanco-Suarez J, Dibas M, Mokin M, Yavagal D, Jovin T, Ortega-Gutierrez S. Mediation Analysis of Acute Carotid Stenting in Tandem Lesions. Neurology 2024, 103: e209617. PMID: 38959444, DOI: 10.1212/wnl.0000000000209617.Peer-Reviewed Original ResearchConceptsAcute carotid artery stentingCarotid artery stentingEndovascular therapyNon-CA groupFunctional outcomesTandem lesionsAnterior circulation tandem lesionsTreated with endovascular therapyMulticenter retrospective cohort studyCarotid artery stenting groupAssociated with better functional outcomesFavorable functional outcomeAcute carotid stentingRetrospective cohort studyAssociated with functional outcomePredictor of functional outcomeCervical lesionsMedian ageModified ThrombolysisReperfusion rateCohort studyPathophysiological mechanismsArtery stentingCarotid stentingReperfusionAutomated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion
Mak A, Matouk C, Avery E, Behland J, Haider S, Frey D, Madai V, Vajkoczy P, Griessenauer C, Zand R, Hendrix P, Abedi V, Sanelli P, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S, Malhotra A. Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion. PLOS ONE 2024, 19: e0304962. PMID: 38870240, PMCID: PMC11175522, DOI: 10.1371/journal.pone.0304962.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imagingLarge vessel occlusionIrreversible ischemic changesPoor functional outcomeFunctional outcomesIschemic changesInfarct volumeAlberta Stroke Program Early CT ScorePredicting poor functional outcomeVessel occlusionFollow-up diffusion-weighted imagingAnterior circulation LVO strokeCTA source imagesReceiver operating characteristic curveExpert human readersPredicting final infarctionASPECTS regionsAdmission CTANon-inferior performanceBaseline CTACT scoreFinal infarctEndovascular therapyHU attenuationValidation cohortPrimary and Secondary Intracerebral Hemorrhage in Pregnant and Nonpregnant Young Adults by SMASH‐UP Criteria
Sariyeva M, Haghighi N, Mitchell A, Booker W, Petersen N, Shields A, Ghoshal S, Agarwal S, Park S, Claassen J, Connolly E, Roh D, Miller E. Primary and Secondary Intracerebral Hemorrhage in Pregnant and Nonpregnant Young Adults by SMASH‐UP Criteria. Journal Of The American Heart Association 2024, 13: e034032. PMID: 38533990, PMCID: PMC11179753, DOI: 10.1161/jaha.123.034032.Peer-Reviewed Original ResearchNonpregnant womenSecondary intracerebral hemorrhagePrimary intracerebral hemorrhageNontraumatic intracerebral hemorrhageIntracerebral hemorrhageIntracerebral hemorrhage pathogenesisIntracerebral hemorrhage characteristicsIn-hospital mortality rateYoung adultsCohort of young adultsTime of dischargeMaternal morbidityNonpregnant adultsUnique pathophysiologyRetrospective analysisFunctional outcomesOdds ratioMortality ratePathogenesisSmall vesselsWomenHemorrhageOddsPathophysiologyMenAnesthetic management for large vessel occlusion acute ischemic stroke with tandem lesions
Farooqui M, Galecio-Castillo M, Hassan A, Divani A, Jumaa M, Ribo M, Petersen N, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Quispe-Orozco D, Tekle W, Sabbagh S, Zaidi S, Gadea M, Prasad A, Qureshi A, De Leacy R, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Turabova C, Rodriguez-Calienes A, Vivanco-Suarez J, Mokin M, Yavagal D, Jovin T, Ortega-Gutierrez S. Anesthetic management for large vessel occlusion acute ischemic stroke with tandem lesions. Journal Of NeuroInterventional Surgery 2024, 17: 139-147. PMID: 38429099, DOI: 10.1136/jnis-2023-021360.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageModified Rankin scoreFavorable functional outcomeAlberta Stroke Program Early CT ScoreNational Institutes of Health Stroke ScaleEndovascular therapyInternal carotid arteryFunctional outcomesAcute ischemic strokeProcedural sedationExcellent recanalizationTandem lesionsAssociated with superior functional outcomesBaseline Alberta Stroke Program Early CT ScoreAnesthetic strategyRecanalization timeAnterior circulation tandem lesionsGeneral anesthesiaAnesthetic techniqueDegree of internal carotid arteryInternal carotid artery stentingOptimal anesthetic strategyIschemic strokeLarge vessel occlusion acute ischemic strokeAcute ischemic stroke patients
2023
Functional and Safety Outcomes of Carotid Artery Stenting and Mechanical Thrombectomy for Large Vessel Occlusion Ischemic Stroke With Tandem Lesions
Farooqui M, Zaidat O, Hassan A, Quispe-Orozco D, Petersen N, Divani A, Ribo M, Abraham M, Fifi J, Guerrero W, Malik A, Siegler J, Nguyen T, Sheth S, Yoo A, Linares G, Janjua N, Galecio-Castillo M, Tekle W, Ringheanu V, Oliver M, Dawod G, Kobsa J, Prasad A, Ikram A, Lin E, Below K, Zevallos C, Gadea M, Qureshi A, Dajles A, Matsoukas S, Rana A, Abdalkader M, Salazar-Marioni S, Soomro J, Gordon W, Vivanco-Suarez J, Turabova C, Mokin M, Yavagal D, Jumaa M, Ortega-Gutierrez S. Functional and Safety Outcomes of Carotid Artery Stenting and Mechanical Thrombectomy for Large Vessel Occlusion Ischemic Stroke With Tandem Lesions. JAMA Network Open 2023, 6: e230736. PMID: 36857054, PMCID: PMC9978940, DOI: 10.1001/jamanetworkopen.2023.0736.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhageCarotid artery stenting groupCarotid artery stentingLarge vessel occlusionNonstented groupDigital subtraction angiographyModified Rankin ScaleMechanical thrombectomyFunctional outcomesCross-sectional studyCervical lesionsSafety outcomesTandem lesionsMRS scoreSubtraction angiographyOdds of favorable functional outcomeIncreased risk of sICHArtery stentingAnterior circulation tandem lesionsDegree of cervical stenosisRisk of symptomatic intracranial hemorrhageOutcomes of carotid artery stentingCervical internal carotid arteryOdds of symptomatic intracranial hemorrhageInternal carotid artery stenosis
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