2019
Large-scale network architecture and associated structural cortico-subcortical abnormalities in patients with sleep/awake-related seizures
Chiosa V, Ciolac D, Groppa S, Koirala N, Pintea B, Vataman A, Winter Y, Gonzalez-Escamilla G, Muthuraman M, Groppa S. Large-scale network architecture and associated structural cortico-subcortical abnormalities in patients with sleep/awake-related seizures. Sleep 2019, 42: zsz006. PMID: 30753617, DOI: 10.1093/sleep/zsz006.Peer-Reviewed Original ResearchConceptsAwake seizuresSleep seizuresHealthy controlsAwake stateSex-matched healthy controlsRight middle temporal cortexDifferent epilepsy typesVolume of hippocampusBrain networksMiddle temporal cortexEpilepsy typePathophysiological alterationsSubcortical abnormalitiesPatientsTemporal cortexSeizuresSubcortical regionsSuperior temporalBilateral insulaOrbitofrontal cortexSleepParietal regionsAbnormalitiesRight hemisphereStructural correlates
2018
Deep Brain Stimulation and L-DOPA Therapy: Concepts of Action and Clinical Applications in Parkinson's Disease
Muthuraman M, Koirala N, Ciolac D, Pintea B, Glaser M, Groppa S, Tamás G, Groppa S. Deep Brain Stimulation and L-DOPA Therapy: Concepts of Action and Clinical Applications in Parkinson's Disease. Frontiers In Neurology 2018, 9: 711. PMID: 30210436, PMCID: PMC6119713, DOI: 10.3389/fneur.2018.00711.Peer-Reviewed Original ResearchDeep brain stimulationL-dopa therapyParkinson's diseaseBrain stimulationEffects of DBSL-DOPAImpact of DBSNon-motor symptomsEffective treatment optionEvidence-based therapiesEffective pharmacological therapyCentral nervous systemBrain networksPerioperative algorithmSpecific brain networksDopaminergic medicationPharmacological therapyClinical effectsMotor symptomsPD patientsPharmacodynamic effectsPharmacological treatmentTherapy optionsTreatment optionsFirst complication