2025
Association of Causative Pathogens With Acute Kidney Injury in Adult Patients With Community-Onset Sepsis
Pant P, Chihara S, Krishnamoorthy V, Treggiari M, Messina J, Privratsky J, Raghunathan K, Ohnuma T. Association of Causative Pathogens With Acute Kidney Injury in Adult Patients With Community-Onset Sepsis. Critical Care Explorations 2025, 7: e1219. PMID: 39937578, PMCID: PMC11826047, DOI: 10.1097/cce.0000000000001219.Peer-Reviewed Original ResearchConceptsAcute kidney injuryOdds of acute kidney injuryDevelopment of acute kidney injuryCommunity-onset sepsisAdult patientsKidney injuryAssociated with increased odds of AKICausative pathogenPINC AI Healthcare DatabaseAcute kidney injury riskMultilevel logistic regressionGlobal Outcomes serum creatinine criteriaAssociated with decreased oddsAssociated with increased oddsSerum creatinine criteriaStage 1 AKIStage 3 AKIStage 2 AKIRetrospective cohort studyCritically ill patientsDay of admissionE. coli infectionCommunity-onsetCreatinine criteriaMedian age
2024
Association of Early Dexmedetomidine Utilization With Clinical Outcomes After Moderate-Severe Traumatic Brain Injury: A Retrospective Cohort Study
Liu S, Kelly-Hedrick M, Komisarow J, Hatfield J, Ohnuma T, Treggiari M, Colton K, Arulraja E, Vavilala M, Laskowitz D, Mathew J, Hernandez A, James M, Raghunathan K, Krishnamoorthy V. Association of Early Dexmedetomidine Utilization With Clinical Outcomes After Moderate-Severe Traumatic Brain Injury: A Retrospective Cohort Study. Anesthesia & Analgesia 2024, 139: 366-374. PMID: 38335145, PMCID: PMC11250935, DOI: 10.1213/ane.0000000000006869.Peer-Reviewed Original ResearchLength of stayTraumatic brain injuryImprove patient outcomesModerate-severe TBIRetrospective cohort studyMechanical ventilationMechanically ventilated patientsDexmedetomidine exposureDay of admissionCohort studyHospital mortalityOdds of hospital mortalityPatient outcomesAssociated with reduced oddsCohort of critically ill adult patientsPrimary outcome of hospital mortalityReduce length of stayHospital costsAssociated with oddsOutcome of hospital mortalityCritically ill adult patientsDay of ICU admissionHospital length of stayIll adult patientsPublic health problem
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