White matter abnormalities in adolescents with major depressive disorder
Bessette KL, Nave AM, Caprihan A, Stevens MC. White matter abnormalities in adolescents with major depressive disorder. Brain Imaging And Behavior 2013, 8: 531-541. PMID: 24242685, DOI: 10.1007/s11682-013-9274-8.Peer-Reviewed Original ResearchConceptsMajor depressive disorderWhite matter abnormalitiesDiffusion tensor imagingDepressive disorderFrontal lobeWhole brainRegional white matter abnormalitiesRight thalamic radiationOlder depressed patientsTract-based spatial statisticsCorpus callosum genuFrontal lobe tractsFractional anisotropy valuesLower FAAbnormal white matter microstructureInferior longitudinal fasciculusWhite matter connectionsWhite matter microstructureInternal capsuleExternal capsuleFA abnormalitiesDepressed patientsHealthy controlsAdolescents ages 13Posterior limbDTI-measured white matter abnormalities in adolescents with Conduct Disorder
Haney-Caron E, Caprihan A, Stevens MC. DTI-measured white matter abnormalities in adolescents with Conduct Disorder. Journal Of Psychiatric Research 2013, 48: 111-120. PMID: 24139595, PMCID: PMC3863548, DOI: 10.1016/j.jpsychires.2013.09.015.Peer-Reviewed Original ResearchConceptsFractional anisotropyAxial diffusivityWhite matter microstructureMicrostructural abnormalitiesLong-range white matter connectionsWhite matter microstructural abnormalitiesWhite matter abnormalitiesDiffusion tensor imaging (DTI) findingsAnatomical connectivity abnormalitiesLower fractional anisotropySuperior corona radiataAbnormal white matter microstructureBrain white matter microstructureDifferent brain regionsWhite matter connectionsTemporal lobe regionsFronto-occipital fasciculusTwo-sample t-testFunctional neuroimaging studiesCD ageCD adolescentsMajor white matterImaging findingsRadial diffusivity measurementsStudy group