2023
A Mouse Model of MHV‐1 Virus Infection for Study of Acute and Long COVID Infection
Masciarella A, Di Gregorio D, Ramamoorthy R, Hussain H, Jayakumar A, Paidas M. A Mouse Model of MHV‐1 Virus Infection for Study of Acute and Long COVID Infection. Current Protocols 2023, 3: e896. PMID: 37867460, PMCID: PMC10606938, DOI: 10.1002/cpz1.896.Peer-Reviewed Original ResearchConceptsSARS-CoV-2Pathological changesMouse modelTransgenic miceLong-term organ dysfunctionSARS-CoV-2 pathophysiologyIrreversible neurological complicationsPotential therapeutic interventionsAvailable human dataBiosafety level 2 laboratoryNon-human primatesBiosafety level 3 laboratoryNeurological complicationsOrgan dysfunctionAcute stageClinical symptomsLong-term effectsSevere casesClinical observationsViral infectionTherapeutic interventionsMHV-1Animal preparationsWeight lossBSL-3 laboratory
2009
Pulmonary embolism in pregnancy
Bourjeily G, Paidas M, Khalil H, Rosene-Montella K, Rodger M. Pulmonary embolism in pregnancy. The Lancet 2009, 375: 500-512. PMID: 19889451, DOI: 10.1016/s0140-6736(09)60996-x.Peer-Reviewed Original ResearchConceptsPulmonary embolismRisk of complicationsBest possible treatmentPotential adverse effectsAppropriate prophylaxisVenous thromboembolismRisk stratificationVenous stasisPregnant womenVascular damageVirchow's triadFetal teratogenicityMaternal mortalityPharmacological treatmentTherapeutic interventionsPregnancyPossible treatmentAccurate diagnosisDiagnostic testingRight populationAdverse effectsEmbolismMortalityPhysiological changesDiagnosis