2005
Protein Z, protein S levels are lower in patients with thrombophilia and subsequent pregnancy complications
PAIDAS MJ, KU D, LEE M, MANISH S, THURSTON A, LOCKWOOD CJ, ARKEL YS. Protein Z, protein S levels are lower in patients with thrombophilia and subsequent pregnancy complications. Journal Of Thrombosis And Haemostasis 2005, 3: 497-501. PMID: 15748239, DOI: 10.1111/j.1538-7836.2005.01158.x.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesNormal pregnancy outcomeProtein S levelsPZ levelsPregnancy outcomesProtein SSubsequent pregnancy complicationsProtein ZAdditional risk factorsFree PS antigenPregnancy complicationsPregnant controlsThird trimesterPlasma levelsRisk factorsPatientsThrombophiliaPS antigenS levelsWomenSignificant decreasePS levelsOutcomesLow levelsTrimester
2004
Normal pregnancy is associated with the development of protein S and protein Z antibodies, independent of PS and PZ levels
Paidas M, Ku D, Arkel Y, Triche E, Fortunato C, Hamar B, Ku E, Lockwood C. Normal pregnancy is associated with the development of protein S and protein Z antibodies, independent of PS and PZ levels. American Journal Of Obstetrics And Gynecology 2004, 191: s140. DOI: 10.1016/j.ajog.2004.10.393.Peer-Reviewed Original ResearchProtein S Free Antigen Levels and the Occurrence of IgG and IgM Antibodies to Protein S in Normal Pregnancy.
Arkel Y, Ku D, Paidas M, Fortunato C, Ku E, Lockwood C. Protein S Free Antigen Levels and the Occurrence of IgG and IgM Antibodies to Protein S in Normal Pregnancy. Blood 2004, 104: 3993. DOI: 10.1182/blood.v104.11.3993.3993.Peer-Reviewed Original ResearchAdverse pregnancy outcomesNormal pregnancyIgM antibodiesProtein SPS IgGAntigen levelsReference rangeFree PS antigen levelsEvaluation of thrombophiliaPS antigen levelsNon-pregnant controlsNumber of patientsNon-pregnant donorsNon-pregnant valuesOccurrence of IgGAnticardiolipin syndromeProthrombotic processesPregnancy patientsPregnancy outcomesAutoimmune diseasesTrimester samplesHemostatic systemImmune responseHigh riskPregnancyElevated sEPCR and PAI-1 Levels, but Not sThrombomodulin Levels in Normal Pregnancy.
Arkel Y, Paidas M, Ku D, Triche E, Lam X, Ku E, Lockwood C. Elevated sEPCR and PAI-1 Levels, but Not sThrombomodulin Levels in Normal Pregnancy. Blood 2004, 104: 3996. DOI: 10.1182/blood.v104.11.3996.3996.Peer-Reviewed Original ResearchEndothelial protein C receptorAdverse pregnancy outcomesPro-inflammatory cytokinesNormal pregnancyProtein C systemDecidual cellsEndothelial cellsProtein SEndometrial decidual cellsNon-pregnant controlsProtein C receptorCell surface proteinsPlasminogen activator inhibitorCell-surface thrombomodulinPregnancy outcomesProthrombotic statePlasma thrombomodulinNP patientsEC damageSurface proteinsControl of thrombosisSTM levelsTrimester samplesPregnancyFibrinolytic system