2025
Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective
Ameral V, Sofuoglu M, Kelly M. Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective. Expert Review Of Clinical Pharmacology 2025, ahead-of-print: 1-8. PMID: 40047379, DOI: 10.1080/17512433.2025.2472837.Peer-Reviewed Original ResearchSmoking cessationE-cigarettesEvidence-based clinical guidelinesEfficacy of e-cigarettesBenefits of e-cigarettesSmoking cessation treatmentHarm reduction optionsHarm reduction principlesNicotine replacement therapyNicotine e-cigarettesQuality of lifeIncreased life expectancyNicotine useCessation treatmentClinical guidelinesNicotineSmokingLife expectancyCigarette smokingClinical pharmacology perspectivePharmacological perspectiveClinical practiceHigh riskLong-term effectsReplacement therapyThe bidirectional relationship between pain and tobacco use: Insights from the longitudinal Population Assessment of Tobacco and Health (PATH) study
Costa G, Nunes J, Suh R, Sofuoglu M, Aquino J. The bidirectional relationship between pain and tobacco use: Insights from the longitudinal Population Assessment of Tobacco and Health (PATH) study. Drug And Alcohol Dependence 2025, 268: 112552. PMID: 39848133, PMCID: PMC11832315, DOI: 10.1016/j.drugalcdep.2025.112552.Peer-Reviewed Original ResearchConceptsDaily smokingDaily cigarette smokingChronic painDevelopment of painCigarette smokingTobacco smokePopulation Assessment of Tobacco and Health StudyBaseline painAlternative tobacco product usePersistent painTobacco product useDevelopment of persistent painYears of longitudinal dataHealth StudyTobacco useNo/low painPreventable causeSmoking outcomesBidirectional relationshipSurvival analysisSmokingPopulation AssessmentAge categoriesIncreased riskSurvey population
2014
Chapter Twelve Cognitive Effects of Nicotine
Sofuoglu M, Herman A, Robinson C, Waters A. Chapter Twelve Cognitive Effects of Nicotine. 2014, 367-385. DOI: 10.1016/b978-0-12-418679-8.00012-5.Peer-Reviewed Original ResearchCognitive-enhancing effectsPrefrontal cortexCognitive functionCognitive deficitsEpisodic memory performanceFine motor skillsNicotine addictionMemory performanceCognitive effectsMotor skillsEffects of nicotineIndividual factorsNicotine administrationFlexibility functionMemoryCortexDeficitsAddictionΑ7 nicotinic acetylcholine receptorEffective treatment strategiesNicotinic acetylcholine receptorsNicotineRelease of neurotransmittersΑ4β2Cigarette smoking
1998
Effects of cotinine on cigarette self-administration
Hatsukami D, Lexau B, Nelson D, Pentel P, Sofuoglu M, Goldman A. Effects of cotinine on cigarette self-administration. Psychopharmacology 1998, 138: 184-189. PMID: 9718288, DOI: 10.1007/s002130050661.Peer-Reviewed Original ResearchConceptsDoses of cotinineWithdrawal symptomsCigarette withdrawal symptomsEffects of cotinineNicotine serum levelsSelective modulatory effectNicotine withdrawal symptomsNumber of cigarettesEffects of nicotineMetabolite of nicotineSubjective responsesNicotine patchSerum levelsCigarette smokingNicotine intakeModulatory effectsCarbon monoxide levelsCotinineRandomized orderPlaceboBeneficial effectsCigarettesOutcome variablesDosesSymptoms
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