2016
Efficacy of Endovascular Treatment for Occlusive Lesions of a Single M2 Branch in Non-recombinant Tissue Plasminogen Activator Treated Patients
Onda T, Nakazaki M, Nomura T, Sasaki M, Yonemasu Y, Hashimoto Y, Takahashi A, Honda O, Daibou M, Nonaka T. Efficacy of Endovascular Treatment for Occlusive Lesions of a Single M2 Branch in Non-recombinant Tissue Plasminogen Activator Treated Patients. Journal Of Neuroendovascular Therapy 2016, 11: oa.2016-0024. DOI: 10.5797/jnet.oa.2016-0024.Peer-Reviewed Original Research
2008
Olfactory ensheathing cells exhibit unique migratory, phagocytic, and myelinating properties in the X‐irradiated spinal cord not shared by Schwann cells
Lankford KL, Sasaki M, Radtke C, Kocsis JD. Olfactory ensheathing cells exhibit unique migratory, phagocytic, and myelinating properties in the X‐irradiated spinal cord not shared by Schwann cells. Glia 2008, 56: 1664-1678. PMID: 18551623, DOI: 10.1002/glia.20718.Peer-Reviewed Original ResearchConceptsCentral nervous systemSpinal cordSchwann cellsOligodendrocyte progenitor cellsNormal central nervous systemMigratory propertiesOX-42 stainingNormal spinal cordOlfactory Ensheathing CellsMyelin-forming cellsDemyelinated lesionsHost axonsPhagocytic phenotypePoor survivalSubsequent lesionsNervous systemWhite matterCordLimited survivalOECsMigratory capabilityProgenitor cellsTransplantationX-irradiationLesions
2007
Demyelinating diseases and potential repair strategies
Radtke C, Spies M, Sasaki M, Vogt PM, Kocsis JD. Demyelinating diseases and potential repair strategies. International Journal Of Developmental Neuroscience 2007, 25: 149-153. PMID: 17408905, PMCID: PMC2692731, DOI: 10.1016/j.ijdevneu.2007.02.002.Peer-Reviewed Original ResearchConceptsMultiple sclerosisInjury modelSpinal cord injuryCell-based strategiesAxon lossNerve compressionNeuroprotective potentialCord injuryFunctional outcomeClinical studiesMS lesionsTherapeutic goalsVulnerable axonsCellular transplantationNeurological disordersDemyelinationRemyelinationNeuroprotectionPotential repair strategiesCell typesSclerosisTransplantationInjuryLesionsAxons
2004
Autologous transplantation of expanded neural precursor cells into the demyelinated monkey spinal cord
Oka S, Honmou O, Akiyama Y, Sasaki M, Houkin K, Hashi K, Kocsis JD. Autologous transplantation of expanded neural precursor cells into the demyelinated monkey spinal cord. Brain Research 2004, 1030: 94-102. PMID: 15567341, DOI: 10.1016/j.brainres.2004.09.062.Peer-Reviewed Original ResearchConceptsNeural precursor cellsAutologous transplantationSpinal cordPrecursor cellsSubventricular zoneAdult primate brainMonkey spinal cordCentral nervous system axonsPresence of mitogensAdult nonhuman primatesNon-human primatesNeurological deficitsDemyelinated lesionsDorsal columnsIntraspinal injectionElectron microscopic examinationControl lesionsLesion sitePrimate brainPeripheral patternMyelinated axonsTransplantationLesionsNonhuman primatesCordIdentified Olfactory Ensheathing Cells Transplanted into the Transected Dorsal Funiculus Bridge the Lesion and Form Myelin
Sasaki M, Lankford KL, Zemedkun M, Kocsis JD. Identified Olfactory Ensheathing Cells Transplanted into the Transected Dorsal Funiculus Bridge the Lesion and Form Myelin. Journal Of Neuroscience 2004, 24: 8485-8493. PMID: 15456822, PMCID: PMC2605369, DOI: 10.1523/jneurosci.1998-04.2004.Peer-Reviewed Original ResearchConceptsSprague-DawleyOlfactory bulbTransection siteMyelinated axonsLesion zoneForm myelinOpen field locomotor behaviorAdult olfactory bulbTransection lesionTransplantation groupPattern of repairSD ratsSpinal cordLesion areaLesionsCellular elementsImproved locomotionAxonsLocomotor behaviorMyelinGFP cellsGreen fluorescent proteinCellsAnti-GFP antibodyDiscrete bundles