2025
Contemporary Bypass Techniques in Hybrid Revascularization
Olutola O, Vega P, Pelletier M. Contemporary Bypass Techniques in Hybrid Revascularization. 2025, 127-138. DOI: 10.1007/978-3-031-87302-7_12.Peer-Reviewed Original ResearchCoronary artery bypass graftingLeft internal mammary arteryMinimally invasive direct coronary artery bypassPercutaneous coronary interventionHybrid coronary revascularizationCardiac surgeonsBypass graftingAssociated with lower perioperative mortalitySimultaneous coronary artery bypass graftingLeft internal mammary artery bypassHybrid operating suiteLIMA-LAD bypassInterventional cardiologistsLeft anterior descending (LAD) arteryRobotic-assisted approachOff-pump surgeryLow perioperative mortalityHigh-risk patientsInternal mammary artery graftsMinimally invasive techniquesCoronary artery bypassArtery bypass graftingInternal mammary arteryMammary artery graftsSingle-vessel diseaseDiaphragm dysfunction from phrenic nerve injuries during LVAD or heart transplant: Positive role of diaphragm pacing
Boutros C, Elmo M, Carl N, Abu-Omar Y, Arora R, Elgudin Y, Gray K, Pelletier M, Onders R. Diaphragm dysfunction from phrenic nerve injuries during LVAD or heart transplant: Positive role of diaphragm pacing. JHLT Open 2025, 9: 100281. PMID: 40520816, PMCID: PMC12166398, DOI: 10.1016/j.jhlto.2025.100281.Peer-Reviewed Original ResearchNon-invasive ventilationLeft ventricular assist deviceDiaphragm pacingHeart transplantationMechanical ventilationNerve injurySingle-center cohort studyPhrenic nerve dysfunctionPhrenic nerve injuryLeft ventricular assist device recipientsPhrenic injuryDiaphragm dysfunctionDifficulty weaningNerve dysfunctionNerve injuresCase seriesDiaphragm functionMV weaningDP useAdverse eventsCohort studyVentricular assist deviceHTxExploratory case seriesTransplantation(432) Enhanced Recovery After Surgery (ERAS): Early Phrenic Nerve/Diaphragm Dysfunction Analysis and Treatment in Lung Transplant Patients
Onders R, Elmo M, Carl N, Elgudin Y, Abu-Omar Y, Gray K, Pelletier M, Arora R, Kilaru S, Schilz R. (432) Enhanced Recovery After Surgery (ERAS): Early Phrenic Nerve/Diaphragm Dysfunction Analysis and Treatment in Lung Transplant Patients. The Journal Of Heart And Lung Transplantation 2025, 44: s217. DOI: 10.1016/j.healun.2025.02.439.Peer-Reviewed Original Research
2024
Transcatheter or surgical aortic valve replacement in pregnant women? A comprehensive review of the current literature.
Kuchibhatla A, Soghrati N, Saleh Y, Rushing G, Halim M, Pelletier M, Baeza C, El-Diasty M. Transcatheter or surgical aortic valve replacement in pregnant women? A comprehensive review of the current literature. Journal Of Invasive Cardiology 2024, 37 PMID: 39453868, DOI: 10.25270/jic/24.00065.Peer-Reviewed Original ResearchRandomized study of temporary diaphragm pacing for enhanced recovery after surgery in cardiac surgery patients at risk of prolonged mechanical ventilation
Hungate J, Onders R, Diasty M, Abu-Omar Y, Arora R, Baeza C, Elgudin Y, Gray K, Markowitz A, Pelletier M, Ribeiro I, Vega P, Rushing G, Sabik J. Randomized study of temporary diaphragm pacing for enhanced recovery after surgery in cardiac surgery patients at risk of prolonged mechanical ventilation. JTCVS Open 2024, 22: 76-84. PMID: 39780786, PMCID: PMC11704535, DOI: 10.1016/j.xjon.2024.09.031.Peer-Reviewed Original ResearchProlonged mechanical ventilationStandard of care groupRisk of prolonged mechanical ventilationMechanical ventilationCardiac surgeryDiaphragmatic pacingDiaphragm pacingTreatment groupsRandomized trialsHistory of chronic obstructive pulmonary diseaseLeft ventricular ejection fractionIntra-aortic balloon pumpDecrease mechanical ventilationCardiac surgery patientsVentricular ejection fractionHigh-risk patientsMulticenter randomized trialCare groupEnhanced recoveryChronic obstructive pulmonary diseaseRelative risk reductionIntensive care unitStandard of carePredictive enrichment strategiesObstructive pulmonary diseaseThe prognostic utility of galectin-3 in patients undergoing cardiac surgery: a scoping review
Shah A, Ding Y, Walji D, Rabinovich G, Pelletier M, El-Diasty M. The prognostic utility of galectin-3 in patients undergoing cardiac surgery: a scoping review. Biomarkers 2024, 29: 485-493. PMID: 39422445, DOI: 10.1080/1354750x.2024.2415073.Peer-Reviewed Original ResearchConceptsAssociated with acute kidney injuryPostoperative atrial fibrillationGal-3 levelsLeft ventricular reverse remodelingCardiac surgeryAdverse outcomesGal-3Clinical risk prediction scorePreoperative plasma levelsVentricular reverse remodelingEuroSCORE II modelPlasma Gal-3 levelsPostoperative adverse outcomesAcute kidney injuryGalectin-3Group of patientsPredicting adverse outcomesRisk prediction scorePostoperative morbidityReverse remodelingPostoperative mortalityElectronic database searchPrognostic utilityAdult patientsKidney injuryCurrent Role of Cardiac Magnetic Resonance for the Clinical Decision-Making Process in Transcatheter Aortic Valve Replacement
Dallan L, Feroze R, Jarrett C, Yoon S, Rajagopalan V, Walker J, Baeza C, Pelletier M, Al-Kindi S, Ukaigwe A, Filby S, Rajagopalan S, Attizzani G, Rashid I. Current Role of Cardiac Magnetic Resonance for the Clinical Decision-Making Process in Transcatheter Aortic Valve Replacement. Cardiovascular Revascularization Medicine 2024, 65: 58. DOI: 10.1016/j.carrev.2024.04.130.Peer-Reviewed Original ResearchElevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement
Feroze R, Kang P, Dallan L, Akula N, Galo J, Yoon S, Ukaigwe A, Filby S, Baeza C, Pelletier M, Rushing G, Rajagopalan S, Al‐Kindi S, Rashid I, Attizzani G. Elevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2024, 104: 1119-1128. PMID: 38952304, DOI: 10.1002/ccd.31136.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAgedAged, 80 and overAortic ValveAortic Valve StenosisArea Under CurveAtrioventricular BlockBundle-Branch BlockCardiac Pacing, ArtificialFemaleFibrosisHeart Conduction SystemHumansMagnetic Resonance Imaging, CineMaleMyocardiumPacemaker, ArtificialPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsTranscatheter aortic valve replacementCardiac magnetic resonance imagingLate gadolinium enhancementRight bundle branch blockArea under the receiver operating characteristic curveAortic valve replacementReceiver operating curveMyocardial fibrosisPost-TAVRConduction defectsBundle branch blockAssociations of myocardial fibrosisExtracellular volumeConduction diseaseValve replacementGadolinium enhancementPermanent pacemakerConduction abnormalitiesConduction deficitsHeart blockBranch blockRisk of heart blockSeptal late gadolinium enhancementMyocardial extracellular volume fractionBaseline conduction diseasePericardial fluid troponin in cardiac surgery
Fatehi Hassanabad A, El-Sherbini A, Cherif I, Ahmad B, Gonzalez A, Pelletier M, Fedak P, El-Diasty M. Pericardial fluid troponin in cardiac surgery. Clinica Chimica Acta 2024, 559: 119722. PMID: 38734224, DOI: 10.1016/j.cca.2024.119722.Peer-Reviewed Original ResearchConceptsCardiac surgeryPericardial fluidTroponin levelsLevels of cardiac troponinPF levelsCardiac troponin levelsTroponin changesGoogle Scholar databasesTroponin concentrationsCardiac troponinProcedure typeClinical significancePrimary outcomeSurgerySecondary outcomesBiologically active factorsBlinded reviewersPreferred Reporting ItemsFull-text reviewTroponinInclusion criteriaPatientsPathological changesScholar databasesSystematic review(514) Diaphragm Dysfunction from Phrenic Nerve Injuries During LVAD or Heart Transplants: Positive Role of Diaphragm Pacing
Onders R, Elmo M, Carl N, Abu-Omar Y, Elgudin Y, Aorora R, Gray K, Pelletier M. (514) Diaphragm Dysfunction from Phrenic Nerve Injuries During LVAD or Heart Transplants: Positive Role of Diaphragm Pacing. The Journal Of Heart And Lung Transplantation 2024, 43: s254. DOI: 10.1016/j.healun.2024.02.1159.Peer-Reviewed Original Research(721) Current Utilization of Diaphragm Pacing in Lung Transplant Patients: Identifying and Treating Phrenic and Diaphragm Function Abnormalities
Onders R, Elmo M, Carl N, Elgudin Y, Abu-Omar Y, Gray K, Pelletier M, Arora R, Kilaru S, Schilz R. (721) Current Utilization of Diaphragm Pacing in Lung Transplant Patients: Identifying and Treating Phrenic and Diaphragm Function Abnormalities. The Journal Of Heart And Lung Transplantation 2024, 43: s344-s345. DOI: 10.1016/j.healun.2024.02.537.Peer-Reviewed Original Research400.13 Current Role of Cardiac Magnetic Resonance for the Clinical Decision-Making Process in Transcatheter Aortic Valve Replacement
Dallan L, Feroze R, Jarrett C, Yoon S, Rajagopalan V, Walker J, Baeza C, Pelletier M, Al-Kindi S, Ukaigwe A, Filby S, Rajagopalan S, Attizzani G, Rashid I. 400.13 Current Role of Cardiac Magnetic Resonance for the Clinical Decision-Making Process in Transcatheter Aortic Valve Replacement. JACC Cardiovascular Interventions 2024, 17: s46. DOI: 10.1016/j.jcin.2024.01.183.Peer-Reviewed Original Research
2023
TCT-248 Assessment of Coronary Cannulation, Commissure and Coronary Alignment Post-TAVR With the New Supra-Annular, Self-Expanding Evolut FX System
Attizzani G, Gabasha S, Filby S, Dallan L, Ukaigwe A, Elgudin Y, Rushing G, Pelletier M, Baeza C, Yoon S. TCT-248 Assessment of Coronary Cannulation, Commissure and Coronary Alignment Post-TAVR With the New Supra-Annular, Self-Expanding Evolut FX System. Journal Of The American College Of Cardiology 2023, 82: b97. DOI: 10.1016/j.jacc.2023.09.255.Peer-Reviewed Original ResearchTemporal trends in mortality of aortic dissection and rupture in the UK, Japan, the USA and Canada
Hibino M, Verma S, Jarret C, Shimamura J, Verma R, Hibino H, Baeza C, Aune D, Yanagawa B, Usui A, Nienaber C, Pelletier M. Temporal trends in mortality of aortic dissection and rupture in the UK, Japan, the USA and Canada. Heart 2023, 110: 331-336. PMID: 37648437, DOI: 10.1136/heartjnl-2023-323042.Peer-Reviewed Original ResearchConceptsAge-standardised mortality ratesAge-standardised mortalityJoinpoint regressionAortic dissectionWHO mortality databaseCompare mortality trendsAnnual percentage changeMortality rateStudy periodAortic ruptureMortality trendsMortality DatabaseMortality of aortic dissectionAortic aneurysm rupturePercentage changeJoinpointTemporal trendsAortic emergenciesLower mortalityClinical outcomesAneurysm ruptureMortalityDissectionCanadaUKComparing results of bypass surgery and percutaneous coronary intervention for left main disease by surgical revascularization pump strategy
Jarrett C, Pelletier M, Abu-Omar Y, Baeza C, Elgudin Y, Markowitz A, Zhou Z, Redfors B, Dressler O, Kappetein A, Serruys P, Stone G, Sabik J. Comparing results of bypass surgery and percutaneous coronary intervention for left main disease by surgical revascularization pump strategy. JTCVS Open 2023, 16: 372-388. PMCID: PMC11884416, DOI: 10.1016/j.xjon.2023.03.018.Peer-Reviewed Original ResearchOn-pump coronary artery bypass graftingCoronary artery bypass graftingOff-pump coronary artery bypass graftingArtery bypass graftingComposite end pointIschemia-driven revascularizationPercutaneous coronary interventionBypass graftingCoronary interventionEnd pointsBypass surgeryOn-pump coronary artery bypass grafting groupOutcomes of off-pump coronary artery bypass graftingComposite study end-pointComposite outcome of deathMyocardial infarctionCoronary artery bypass surgeryCoronary artery bypass grafting groupResults of bypass surgeryStudy end pointOutcome of deathArtery bypass surgeryKaplan-Meier estimatesOff-pump strategyRate of deathMortality trends of aortic stenosis in high-income countries from 2000 to 2020
Hibino M, Pandey A, Hibino H, Verma R, Aune D, Yanagawa B, Takami Y, Bhatt D, Attizzani G, Pelletier M, Verma S. Mortality trends of aortic stenosis in high-income countries from 2000 to 2020. Heart 2023, 109: 1473-1478. PMID: 37208159, DOI: 10.1136/heartjnl-2023-322397.Peer-Reviewed Original ResearchConceptsAge-standardised mortality ratesAge-specific mortality ratesMortality trendsCrude mortality rateHigh-income countriesJoinpoint regressionCalculate age-specific mortality ratesMortality rateWHO mortality databaseAnnual percentage changeYounger age groupsMortality DatabaseAortic stenosisPercentage changeJoinpointAge groupsMortalityPersonsAustraliaDecreasing trendYearsCountriesObservation periodStenosisWHOTemporary Diaphragm Pacing Wires in Lung Transplant Patients: Diagnostic and Therapeutic Utilization
Onders R, Elmo M, Carl N, Elgudin Y, Abu-Omar Y, Pelletier M, Schilz R. Temporary Diaphragm Pacing Wires in Lung Transplant Patients: Diagnostic and Therapeutic Utilization. The Journal Of Heart And Lung Transplantation 2023, 42: s101. DOI: 10.1016/j.healun.2023.02.1509.Peer-Reviewed Original ResearchVentilator induced diaphragm dysfunctionDP stimulationLung transplant patientsMechanical ventilationDiaphragm pacingDiaphragmatic dysfunctionTransplant patientsDEMG activityNerve recoveryPhrenic nerve recoveryNo device related complicationsGroup 3 patientsLung transplant recipientsMonths post-transplantDevice related complicationsAverage anesthesia timeHyperinflation of lungsRespiratory neuroplasticityDiaphragm dysfunctionChest closureTransplant recipientsMV timePost-transplantRelated complicationsPre-operativelyOutcomes of Status 4 Heart Transplant Candidates: A Nationwide Analysis
Jarrett C, Mahmoud O, Abu-Omar Y, Elgudin Y, Hussian O, Pelletier M, Sabik J, ElAmm C. Outcomes of Status 4 Heart Transplant Candidates: A Nationwide Analysis. The Journal Of Heart And Lung Transplantation 2023, 42: s282. DOI: 10.1016/j.healun.2023.02.643.Peer-Reviewed Original ResearchStatus 4Re-transplantWaitlist survivalHeart diseaseTwo-thirds of patientsCongenital heart diseaseKaplan-Meier methodLog-rank testInotrope-dependent patientsHeart transplant candidatesIschemic heart diseaseNationwide analysisInotrope dependencePrimary endpointIschemic cardiomyopathyHeart transplantationIV inotropesTransplantationUnique patientsTransplant candidatesInotropesPatientsSurvivalCardiomyopathyMonthsThe Fate of Status 6 Heart Transplant Candidates: A Nationwide Analysis
Jarrett C, Mahmoud O, Elgudin Y, Hussian O, Pelletier M, Sabik J, ElAmm C, Abu-Omar Y. The Fate of Status 6 Heart Transplant Candidates: A Nationwide Analysis. The Journal Of Heart And Lung Transplantation 2023, 42: s282. DOI: 10.1016/j.healun.2023.02.644.Peer-Reviewed Original ResearchHeart transplant candidatesTransplant candidatesTwo-thirds of patientsMedian follow-upKaplan-Meier methodLog-rank testAdvanced heart failureNationwide analysisPrimary endpointMedian ageHeart transplantationHeart failureFollow-upUnique patientsPatientsTransplantationMonthsSurvivalHeartTwo-thirdsStatusSTAR filesYearsClinical impact of right ventricular pacing burden in patients with post-transcatheter aortic valve replacement permanent pacemaker implantation
Tsushima T, Al-Kindi S, Dallan L, Fares A, Yoon S, Wheat H, Attizzani G, Baeza C, Pelletier M, Arruda M, Mackall J, Thal S. Clinical impact of right ventricular pacing burden in patients with post-transcatheter aortic valve replacement permanent pacemaker implantation. EP Europace 2023, 25: 1441-1450. PMID: 36794441, PMCID: PMC10105841, DOI: 10.1093/europace/euad025.Peer-Reviewed Original ResearchConceptsRight ventricular pacing burdenTranscatheter aortic valve replacementVentricular pacing burdenPermanent pacemaker implantationPermanent pacemakerHeart failurePacing burdenPPM implantationRetrospective study of consecutive patientsLikelihood of heart failureStudy of consecutive patientsLeft ventricular ejection fractionAssociated with worse outcomesVentricular ejection fractionAortic valve replacementAtrial fibrillation burdenValve implantation depthConsecutive patientsEjection fractionValve replacementPost-TAVRClinical benefitPacemaker implantationRetrospective studySingle-centre
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