2024
Elevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement
Feroze R, Kang P, Dallan L, Akula N, Galo J, Yoon S, Ukaigwe A, Filby S, Baeza C, Pelletier M, Rushing G, Rajagopalan S, Al‐Kindi S, Rashid I, Attizzani G. Elevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2024, 104: 1119-1128. PMID: 38952304, DOI: 10.1002/ccd.31136.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAgedAged, 80 and overAortic ValveAortic Valve StenosisArea Under CurveAtrioventricular BlockBundle-Branch BlockCardiac Pacing, ArtificialFemaleFibrosisHeart Conduction SystemHumansMagnetic Resonance Imaging, CineMaleMyocardiumPacemaker, ArtificialPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsTranscatheter aortic valve replacementCardiac magnetic resonance imagingLate gadolinium enhancementRight bundle branch blockArea under the receiver operating characteristic curveAortic valve replacementReceiver operating curveMyocardial fibrosisPost-TAVRConduction defectsBundle branch blockAssociations of myocardial fibrosisExtracellular volumeConduction diseaseValve replacementGadolinium enhancementPermanent pacemakerConduction abnormalitiesConduction deficitsHeart blockBranch blockRisk of heart blockSeptal late gadolinium enhancementMyocardial extracellular volume fractionBaseline conduction disease
2023
Clinical impact of right ventricular pacing burden in patients with post-transcatheter aortic valve replacement permanent pacemaker implantation
Tsushima T, Al-Kindi S, Dallan L, Fares A, Yoon S, Wheat H, Attizzani G, Baeza C, Pelletier M, Arruda M, Mackall J, Thal S. Clinical impact of right ventricular pacing burden in patients with post-transcatheter aortic valve replacement permanent pacemaker implantation. EP Europace 2023, 25: 1441-1450. PMID: 36794441, PMCID: PMC10105841, DOI: 10.1093/europace/euad025.Peer-Reviewed Original ResearchConceptsRight ventricular pacing burdenTranscatheter aortic valve replacementVentricular pacing burdenPermanent pacemaker implantationPermanent pacemakerHeart failurePacing burdenPPM implantationRetrospective study of consecutive patientsLikelihood of heart failureStudy of consecutive patientsLeft ventricular ejection fractionAssociated with worse outcomesVentricular ejection fractionAortic valve replacementAtrial fibrillation burdenValve implantation depthConsecutive patientsEjection fractionValve replacementPost-TAVRClinical benefitPacemaker implantationRetrospective studySingle-centreCor-Knot Use in SAVR Facilitates Coplanar Angle Adjustment During TAVR.
Hibino M, Palma Dallan L, Yoon S, Pelletier M, Ukaigwe A, Baeza C. Cor-Knot Use in SAVR Facilitates Coplanar Angle Adjustment During TAVR. Journal Of Invasive Cardiology 2023, 35: e108-e109. PMID: 36735874, DOI: 10.25270/jic/22.00156.Peer-Reviewed Original ResearchConceptsCOR-KNOTMinimally invasive cardiac surgeryPreoperative computed tomography scansInvasive cardiac surgeryAortic pressure gradientTrifecta valveCardiac surgeryAortic annulusConduction abnormalitiesParavalvular leakageRenal injuryTomography scanMm HgTAVR proceduresSurgical anatomyOperative timeTAVR valvesTAVRNext dayControl pacingFeasibility and Safety of Exclusive Noncontrast Computed Tomography for Planning of Transcatheter Aortic Valve Implantation With Self-Expandable Valves
Hibino M, Yoon S, Dallan L, Pelletier M, Rushing G, Filby S, Elgudin Y, Ukaigwe A, Baeza C, Attizzani G. Feasibility and Safety of Exclusive Noncontrast Computed Tomography for Planning of Transcatheter Aortic Valve Implantation With Self-Expandable Valves. The American Journal Of Cardiology 2023, 190: 122-124. PMID: 36623398, DOI: 10.1016/j.amjcard.2022.12.018.Peer-Reviewed Original Research
2022
Comparison of Hemodynamic Performance of Transcatheter Aortic Valve Implantation With Supra-Annular Self-Expanding Versus Balloon-Expandable Valves Assessed by Exercise Cardiovascular Magnetic Resonance
Attizzani G, Dallan L, Yoon S, Feroze R, Rajagopalan V, Baeza C, Pelletier M, Al-Kindi S, Rajagopalan S, Rashid I. Comparison of Hemodynamic Performance of Transcatheter Aortic Valve Implantation With Supra-Annular Self-Expanding Versus Balloon-Expandable Valves Assessed by Exercise Cardiovascular Magnetic Resonance. The American Journal Of Cardiology 2022, 178: 169-171. PMID: 35842277, DOI: 10.1016/j.amjcard.2022.06.015.Peer-Reviewed Original ResearchPercutaneous mechanical thrombectomy and extracorporeal membranous oxygenation: A case series
Mously H, Hajjari J, Chami T, Hammad T, Schilz R, Carman T, Elgudin Y, Abu‐Omar Y, Pelletier M, Shishehbor M, Li J. Percutaneous mechanical thrombectomy and extracorporeal membranous oxygenation: A case series. Catheterization And Cardiovascular Interventions 2022, 100: 274-278. PMID: 35686535, DOI: 10.1002/ccd.30295.Peer-Reviewed Original ResearchConceptsPulmonary Embolism Response TeamExtracorporeal membrane oxygenationPulmonary embolismFollow-up periodCardiac arrestPulmonary embolism response team activationHigh-risk pulmonary embolismRetrospective chart review of patientsChart review of patientsExtracorporeal membrane oxygenation initiationMassive pulmonary embolismMedian ECMO durationReview of patientsRight heart strainRetrospective chart reviewSignificant hemodynamic compromisePERT programsLife-threatening diagnosisMassive PEECMO durationMedian agePE diagnosisHemodynamic compromiseSignificant morbidityHeart strainRisk Stratification of New Persistent Left Bundle Branch Block After Transcatheter Aortic Valve Implantation
Tsushima T, Main A, Al-Kindi S, Dallan L, Wheat H, Baeza C, Pelletier M, Arruda M, Mackall J, Thal S, Ohno Y, Lee K, Siqueira D, Kaneko T, Harloff M, Costa G, Barbanti M, Attizzani G. Risk Stratification of New Persistent Left Bundle Branch Block After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2022, 175: 80-87. PMID: 35597627, DOI: 10.1016/j.amjcard.2022.03.053.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionTranscatheter aortic valve implantationPersistent left bundle branch blockAssociated with cardiac mortalityNOP-LBBBLeft bundle branch blockLong-term outcomesBundle branch blockAortic valve implantationCardiac mortalityRisk stratificationComposite outcomeNew-onset persistent left bundle branch blockBranch blockValve implantationRetrospective study of patientsVentricular ejection fractionStudy of patientsHeart failure readmissionEjection fractionPermanent pacemakerRetrospective studyHeart failurePost-TAVIPatientsEndoscopic vs Open Vein Harvest in Drug-Eluting Stents or Bypass Surgery for Left Main Disease Trial
Jarrett C, Pelletier M, Abu-Omar Y, Baeza C, Elgudin Y, Markowitz A, Vega P, Dressler O, Kappetein A, Serruys P, Stone G, Sabik J. Endoscopic vs Open Vein Harvest in Drug-Eluting Stents or Bypass Surgery for Left Main Disease Trial. The Annals Of Thoracic Surgery 2022, 115: 72-78. PMID: 35283098, DOI: 10.1016/j.athoracsur.2021.12.079.Peer-Reviewed Original ResearchConceptsEndoscopic vein harvesting groupCoronary artery bypass graftingOpen vein harvestingEndoscopic vein harvestingIschemia-driven revascularizationOpen vein harvested patientsBlood product transfusionComposite of deathGraft stenosisProduct transfusionVein harvestingEndoscopic vein harvest patientsOpen vein harvesting groupMyocardial infarctionOutcomes of coronary artery bypass graftingPrimary end pointArtery bypass graftingIn-hospital bleedingKaplan-Meier estimatesTime-to-first-event analysisDrug-eluting stentsBypass surgeryBypass graftingVenous graftsEnd points
2021
Redo‐transcatheter aortic valve replacement with the supra‐annular, self‐expandable Evolut platform: Insights from the Transcatheter valve Therapy Registry
Attizzani GF, Dallan LAP, Forrest JK, Reardon MJ, Szeto WY, Liu F, Pelletier M. Redo‐transcatheter aortic valve replacement with the supra‐annular, self‐expandable Evolut platform: Insights from the Transcatheter valve Therapy Registry. Catheterization And Cardiovascular Interventions 2021, 99: 869-876. PMID: 34533891, DOI: 10.1002/ccd.29941.Peer-Reviewed Original ResearchConceptsTranscatheter Valve Therapy RegistryTranscatheter aortic valveRedo-TAVRTVT RegistryRedo transcatheter aortic valve replacementBetter short-term outcomesTotal aortic regurgitationAortic valve replacementLow-risk patientsShort-term outcomesHospital mortalityIndex hospitalizationAortic regurgitationValve replacementDevice successEvolut RSafety profileMyocardial infarctionAortic valveEvolut PROPatientsRegistryMean gradientOutcomesEvolut
2020
Joint preoperative transthoracic and intraoperative transoesophageal echocardiographic assessment of functional mitral regurgitation severity provides better association with long-term mortality
Asher SR, Malzberg GW, Ong CS, Malapero RJ, Wang H, Shekar P, Kaneko T, Pelletier MP, Mallidi H, Heydarpour M, Shook DC, Shernan SK, Fox JA, Muehlschlegel JD, Xu X, Nguyen TB, Sundt TM, Body SC. Joint preoperative transthoracic and intraoperative transoesophageal echocardiographic assessment of functional mitral regurgitation severity provides better association with long-term mortality. Interdisciplinary CardioVascular And Thoracic Surgery 2020, 32: 9-19. PMID: 33313764, PMCID: PMC8600023, DOI: 10.1093/icvts/ivaa230.Peer-Reviewed Original ResearchConceptsFunctional mitral regurgitationAortic valve replacementModerate mitral regurgitationMitral regurgitationMR severityPostoperative mortalityPreoperative transthoracicValve replacementEchocardiographic assessmentLong-term postoperative mortalityAortic valve replacement surgerySeverity of MRCoronary artery bypassLong-term mortalityValve replacement surgeryInduction of anesthesiaIschemic heart diseaseAortic valve diseaseProportional hazards regressionMitral valve repairPrediction of mortalityFunctional mitral regurgitation severityMitral regurgitation severityIntraoperative reassessmentArtery bypassSafety‐net hospitals versus non‐safety centers and clinical outcomes after trans‐catheter aortic valve replacement
Sheikh M, Deo S, Riaz H, Raza S, Altarabsheh S, Wilson B, Elgudin Y, Cmolik B, Pelletier M, Markowitz A. Safety‐net hospitals versus non‐safety centers and clinical outcomes after trans‐catheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2020, 97: e425-e430. PMID: 32681697, DOI: 10.1002/ccd.29123.Peer-Reviewed Original ResearchConceptsValve replacementNational in-patient sampleLength of post-operative stayPropensity-matched cohort of patientsTrans-catheter aortic valve replacementPost-operative stayAortic valve replacementClinical co-variatesCohort of patientsAcute kidney injuryPropensity-matched cohortPost-procedural mortalityPost-procedural outcomesClinical outcomesKidney injurySecondary outcomesIn-patient samplePatientsLow-income patientsSafety-net hospitalHospitalOutcomesSafety-netIncome patientsNon-safety net hospitalsCochrane corner: transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Kolkailah A, Doukky R, Pelletier M, Volgman A, Kaneko T, Nabhan A. Cochrane corner: transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk. Heart 2020, 106: 1043-1045. PMID: 32482670, DOI: 10.1136/heartjnl-2020-316661.Peer-Reviewed Original ResearchNational Outcomes of Surgical Embolectomy for Acute Pulmonary Embolism
Percy E, Shah R, Hirji S, Tartarini R, Yazdchi F, Harloff M, Kaneko T, Pelletier M. National Outcomes of Surgical Embolectomy for Acute Pulmonary Embolism. The Annals Of Thoracic Surgery 2020, 110: 441-447. PMID: 32199827, DOI: 10.1016/j.athoracsur.2020.02.024.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultEmbolectomyFemaleHumansMaleMiddle AgedPulmonary EmbolismRetrospective StudiesTreatment OutcomeUnited StatesYoung AdultConceptsAcute pulmonary embolismCatheter-directed therapySurgical embolectomyPulmonary embolismSystemic thrombolysisContemporary outcomes of patientsTreated with systemic thrombolysisAssociated with increased odds of mortalityHigher in-hospital mortalityOutcomes of patientsIn-hospital mortalityAssociated with increased oddsOdds of mortalityReal-world studyHigh-risk conditionsNational Inpatient SampleSurgical groupIntracranial hemorrhageSaddle embolusBlood transfusionMultidisciplinary treatmentEmbolectomy patientsAtrial fibrillationSurgical patientsContemporary outcomesUtility of 90-Day Mortality vs 30-Day Mortality as a Quality Metric for Transcatheter and Surgical Aortic Valve Replacement Outcomes
Hirji S, McGurk S, Kiehm S, Ejiofor J, Val F, Kolkailah A, Berry N, Sobieszczyk P, Pelletier M, Shah P, O’Gara P, Kaneko T. Utility of 90-Day Mortality vs 30-Day Mortality as a Quality Metric for Transcatheter and Surgical Aortic Valve Replacement Outcomes. JAMA Cardiology 2020, 5: 156-165. PMID: 31851293, PMCID: PMC6990722, DOI: 10.1001/jamacardio.2019.4657.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementSurgical aortic valve replacement proceduresAortic valve replacementHospital performanceEvaluation of hospital performanceValve replacementHospital performance rankingsCohort study analyzed dataMeasure hospital performanceConcomitant coronary artery bypass graftingCoronary artery bypass graftingProcedure-related mortalityOpen-heart proceduresStudy analyzed dataPatient risk profileSurgical aortic valve replacement outcomesTAVR admissionsArtery bypass graftingMedicare beneficiariesMain OutcomesReplacement outcomesOutcome metricsRisk adjustmentBypass graftingRelationship Between Hospital Surgical Aortic Valve Replacement Volume and Transcatheter Aortic Valve Replacement Outcomes
Hirji S, McCarthy E, Kim D, McGurk S, Ejiofor J, Val F, Kolkailah A, Rosner B, Shook D, Nyman C, Berry N, Sobieszczyk P, Pelletier M, Shah P, O’Gara P, Kaneko T. Relationship Between Hospital Surgical Aortic Valve Replacement Volume and Transcatheter Aortic Valve Replacement Outcomes. JACC Cardiovascular Interventions 2020, 13: 335-343. PMID: 32029250, PMCID: PMC8858441, DOI: 10.1016/j.jcin.2019.09.048.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveClinical CompetenceDatabases, FactualFemaleHeart Valve Prosthesis ImplantationHospitals, High-VolumeHospitals, Low-VolumeHumansMaleMedicareOutcome and Process Assessment, Health CareQuality Indicators, Health CareRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementSurgical aortic valve replacementTranscatheter aortic valve replacement outcomesAortic valve replacementValve replacementConcomitant coronary artery bypass graft surgeryGroup 2Aortic valve replacement volumesGroup 1Group 3Group 4Surgical aortic valve replacement volumeCoronary artery bypass graft surgeryTranscatheter aortic valve replacement procedureArtery bypass graft surgeryAortic valve replacement proceduresYear post-procedureOpen-heart proceduresRisk-adjusted odds ratioMultivariate Cox regressionHeart valve proceduresLow-volume centersValve replacement proceduresTAVR admissionsBypass graft surgeryOutcomes After Tricuspid Valve Repair With Ring Versus Suture Bicuspidization Annuloplasty
Hirji S, Yazdchi F, Kiehm S, Landino S, McGurk S, Muehlschlegel J, Singh S, Mallidi H, Pelletier M, Aranki S, Shekar P, Kaneko T. Outcomes After Tricuspid Valve Repair With Ring Versus Suture Bicuspidization Annuloplasty. The Annals Of Thoracic Surgery 2020, 110: 821-828. PMID: 32001230, DOI: 10.1016/j.athoracsur.2019.12.023.Peer-Reviewed Original ResearchConceptsTricuspid valve repairEvent-free survivalTricuspid valve reoperationValve repairTR recurrenceValve reoperationTricuspid regurgitationConcomitant aortic valveCoronary artery bypass grafting proceduresFunctional tricuspid regurgitationTricuspid valve insufficiencyTricuspid valve replacementDevice placement procedureConventional surgical techniquesIn-hospital outcomesBypass grafting proceduresBicuspidization techniqueAortic proceduresRing annuloplastyMidterm outcomesValve insufficiencyValve replacementEchocardiographic profileHeart transplantationMitral valveTranscatheter vs surgical aortic valve replacement in patients with interstitial lung disease
Hirji S, Cote C, Lee J, Kiehm S, McGurk S, Pelletier M, Aranki S, Shekar P, Shah P, Kaneko T. Transcatheter vs surgical aortic valve replacement in patients with interstitial lung disease. Journal Of Cardiac Surgery 2020, 35: 571-579. PMID: 31981435, DOI: 10.1111/jocs.14421.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementInterstitial lung diseaseAortic valve replacementTranscatheter aortic valve replacement patientsIntensive care unitSurgical aortic valve replacement patientsInterstitial lung disease patientsShorter ventilation timeValve replacementOperative mortalityAortic stenosisVentilation timeLung diseaseRisk of postoperative pulmonary complicationsIsolated surgical aortic valve replacementDiagnosis of interstitial lung diseaseAssociated with significantly shorter hospitalRate of postoperative strokeIntensive care unit admissionPostoperative pulmonary complicationsSignificantly shorter hospitalSevere aortic stenosisPermanent pacemaker implantationSymptomatic aortic stenosisThirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery
Hirji SA, Percy ED, Zogg CK, Vaduganathan M, Kiehm S, Pelletier M, Kaneko T. Thirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery. The Annals Of Thoracic Surgery 2020, 110: 484-491. PMID: 31972128, PMCID: PMC7382395, DOI: 10.1016/j.athoracsur.2019.11.042.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementNonindex readmissionsCardiac surgeryNonindex hospitalNonindex hospital readmissionsCoronary artery bypassNational Readmission DatabaseAortic valve replacementCardiac surgery patientsMajor cardiac surgeryPatient risk profileHigh-volume centersUS adult patientsRegionalization of careFragmentation of careComorbidity burdenHospital mortalityIndex readmissionArtery bypassInitial hospitalizationAdult patientsSurgery patientsValve replacementHospital readmissionIndependent predictorsLong-Term Outcomes of Right Minithoracotomy Versus Hemisternotomy for Mitral Valve Repair
Percy E, Hirji S, Yazdchi F, McGurk S, Kiehm S, Cook R, Kaneko T, Shekar P, Pelletier M. Long-Term Outcomes of Right Minithoracotomy Versus Hemisternotomy for Mitral Valve Repair. Innovations Technology And Techniques In Cardiothoracic And Vascular Surgery 2020, 15: 74-80. PMID: 31957524, DOI: 10.1177/1556984519891966.Peer-Reviewed Original ResearchConceptsMitral valve repairMinimally invasive mitral valve repairRight minithoracotomyValve repairLong-term survivalRT groupMitral reoperationMitral repairHS groupIsolated mitral repairCross-clamp timeFollow-up timeShort-term outcomesCox proportional hazards modelsLong-term outcomesRisk-adjusted survivalProportional hazards modelLower hemisternotomyOperative mortalityPatient yearsPostoperative complicationsLonger bypassHemisternotomyExcellent survivalMean age
2019
Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Kolkailah A, Doukky R, Pelletier M, Volgman A, Kaneko T, Nabhan A. Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk. Cochrane Database Of Systematic Reviews 2019, 12: cd013319. PMID: 31860123, PMCID: PMC6984621, DOI: 10.1002/14651858.cd013319.pub2.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementLength of hospital stayLow surgical riskAortic valve replacementTranscatheter aortic valve implantationAcute kidney injuryRisk of PPM implantationRisk of atrial fibrillationSurgical riskAortic valve stenosisRandomised controlled trialsValve replacementAortic valve implantationAtrial fibrillationCardiac deathCertainty of evidenceMyocardial infarctionPPM implantationPermanent pacemakerValve implantationAssociated with shorter lengths of hospital stayNew-onset atrial fibrillationRisk ratioLong-term follow-up dataShorter length of hospital stay
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