2024
Elevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement
Feroze R, Kang P, Dallan L, Akula N, Galo J, Yoon S, Ukaigwe A, Filby S, Baeza C, Pelletier M, Rushing G, Rajagopalan S, Al‐Kindi S, Rashid I, Attizzani G. Elevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2024, 104: 1119-1128. PMID: 38952304, DOI: 10.1002/ccd.31136.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAgedAged, 80 and overAortic ValveAortic Valve StenosisArea Under CurveAtrioventricular BlockBundle-Branch BlockCardiac Pacing, ArtificialFemaleFibrosisHeart Conduction SystemHumansMagnetic Resonance Imaging, CineMaleMyocardiumPacemaker, ArtificialPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsTranscatheter aortic valve replacementCardiac magnetic resonance imagingLate gadolinium enhancementRight bundle branch blockArea under the receiver operating characteristic curveAortic valve replacementReceiver operating curveMyocardial fibrosisPost-TAVRConduction defectsBundle branch blockAssociations of myocardial fibrosisExtracellular volumeConduction diseaseValve replacementGadolinium enhancementPermanent pacemakerConduction abnormalitiesConduction deficitsHeart blockBranch blockRisk of heart blockSeptal late gadolinium enhancementMyocardial extracellular volume fractionBaseline conduction disease
2023
Clinical impact of right ventricular pacing burden in patients with post-transcatheter aortic valve replacement permanent pacemaker implantation
Tsushima T, Al-Kindi S, Dallan L, Fares A, Yoon S, Wheat H, Attizzani G, Baeza C, Pelletier M, Arruda M, Mackall J, Thal S. Clinical impact of right ventricular pacing burden in patients with post-transcatheter aortic valve replacement permanent pacemaker implantation. EP Europace 2023, 25: 1441-1450. PMID: 36794441, PMCID: PMC10105841, DOI: 10.1093/europace/euad025.Peer-Reviewed Original ResearchConceptsRight ventricular pacing burdenTranscatheter aortic valve replacementVentricular pacing burdenPermanent pacemaker implantationPermanent pacemakerHeart failurePacing burdenPPM implantationRetrospective study of consecutive patientsLikelihood of heart failureStudy of consecutive patientsLeft ventricular ejection fractionAssociated with worse outcomesVentricular ejection fractionAortic valve replacementAtrial fibrillation burdenValve implantation depthConsecutive patientsEjection fractionValve replacementPost-TAVRClinical benefitPacemaker implantationRetrospective studySingle-centreCor-Knot Use in SAVR Facilitates Coplanar Angle Adjustment During TAVR.
Hibino M, Palma Dallan L, Yoon S, Pelletier M, Ukaigwe A, Baeza C. Cor-Knot Use in SAVR Facilitates Coplanar Angle Adjustment During TAVR. Journal Of Invasive Cardiology 2023, 35: e108-e109. PMID: 36735874, DOI: 10.25270/jic/22.00156.Peer-Reviewed Original ResearchConceptsCOR-KNOTMinimally invasive cardiac surgeryPreoperative computed tomography scansInvasive cardiac surgeryAortic pressure gradientTrifecta valveCardiac surgeryAortic annulusConduction abnormalitiesParavalvular leakageRenal injuryTomography scanMm HgTAVR proceduresSurgical anatomyOperative timeTAVR valvesTAVRNext dayControl pacing
2021
Redo‐transcatheter aortic valve replacement with the supra‐annular, self‐expandable Evolut platform: Insights from the Transcatheter valve Therapy Registry
Attizzani GF, Dallan LAP, Forrest JK, Reardon MJ, Szeto WY, Liu F, Pelletier M. Redo‐transcatheter aortic valve replacement with the supra‐annular, self‐expandable Evolut platform: Insights from the Transcatheter valve Therapy Registry. Catheterization And Cardiovascular Interventions 2021, 99: 869-876. PMID: 34533891, DOI: 10.1002/ccd.29941.Peer-Reviewed Original ResearchConceptsTranscatheter Valve Therapy RegistryTranscatheter aortic valveRedo-TAVRTVT RegistryRedo transcatheter aortic valve replacementBetter short-term outcomesTotal aortic regurgitationAortic valve replacementLow-risk patientsShort-term outcomesHospital mortalityIndex hospitalizationAortic regurgitationValve replacementDevice successEvolut RSafety profileMyocardial infarctionAortic valveEvolut PROPatientsRegistryMean gradientOutcomesEvolut
2020
Acute kidney injury in renal transplant recipients undergoing cardiac surgery
Hundemer G, Srivastava A, Jacob K, Krishnasamudram N, Ahmed S, Boerger E, Sharma S, Pokharel K, Hirji S, Pelletier M, Safa K, Kulvichit W, Kellum J, Riella L, Leaf D. Acute kidney injury in renal transplant recipients undergoing cardiac surgery. Nephrology Dialysis Transplantation 2020, 36: 185-196. PMID: 32892219, PMCID: PMC7771983, DOI: 10.1093/ndt/gfaa063.Peer-Reviewed Original ResearchConceptsRenal transplant recipientsAcute kidney injuryNon-RTRsCardiac surgeryCalcineurin inhibitorsRisk factorsTransplant recipientsKidney injuryType of cardiac surgeryKidney diseaseRates of acute kidney injuryRisk of acute kidney injuryDeceased donorsGlobal Outcomes criteriaLiving donorsRetrospective cohort studyAssociated with higher ratesChronic kidney diseaseTrough levelsClinical characteristicsAcademic medical centerCohort studySurgeryHigh riskMedical CenterSafety‐net hospitals versus non‐safety centers and clinical outcomes after trans‐catheter aortic valve replacement
Sheikh M, Deo S, Riaz H, Raza S, Altarabsheh S, Wilson B, Elgudin Y, Cmolik B, Pelletier M, Markowitz A. Safety‐net hospitals versus non‐safety centers and clinical outcomes after trans‐catheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2020, 97: e425-e430. PMID: 32681697, DOI: 10.1002/ccd.29123.Peer-Reviewed Original ResearchConceptsValve replacementNational in-patient sampleLength of post-operative stayPropensity-matched cohort of patientsTrans-catheter aortic valve replacementPost-operative stayAortic valve replacementClinical co-variatesCohort of patientsAcute kidney injuryPropensity-matched cohortPost-procedural mortalityPost-procedural outcomesClinical outcomesKidney injurySecondary outcomesIn-patient samplePatientsLow-income patientsSafety-net hospitalHospitalOutcomesSafety-netIncome patientsNon-safety net hospitalsSex-based differences in mitral valve Re-operation after mitral valve repair: Truth or myth?
Hirji S, Guetter C, Trager L, Yazdchi F, Landino S, Lee J, Anastasopulos A, Percy E, McGurk S, Pelletier M, Aranki S, Shekar P, Kaneko T. Sex-based differences in mitral valve Re-operation after mitral valve repair: Truth or myth? The American Journal Of Surgery 2020, 220: 1344-1350. PMID: 32788080, DOI: 10.1016/j.amjsurg.2020.06.069.Peer-Reviewed Original ResearchConceptsRe-operation riskRe-operationMV repairRheumatic diseasesFemale sexMitral valve re-operationMV repair durabilityMedian follow-upMitral valve repairAssociated with rheumatic diseasesSTS risk scoreOperative mortalityValve repairPreoperative profilesAdult patientsFollow-upDisease progressionSex-based differencesRepair durabilityRepair failureWomenRepairRiskLongitudinal analysisSexCochrane corner: transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Kolkailah A, Doukky R, Pelletier M, Volgman A, Kaneko T, Nabhan A. Cochrane corner: transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk. Heart 2020, 106: 1043-1045. PMID: 32482670, DOI: 10.1136/heartjnl-2020-316661.Peer-Reviewed Original ResearchRelationship Between Hospital Surgical Aortic Valve Replacement Volume and Transcatheter Aortic Valve Replacement Outcomes
Hirji S, McCarthy E, Kim D, McGurk S, Ejiofor J, Val F, Kolkailah A, Rosner B, Shook D, Nyman C, Berry N, Sobieszczyk P, Pelletier M, Shah P, O’Gara P, Kaneko T. Relationship Between Hospital Surgical Aortic Valve Replacement Volume and Transcatheter Aortic Valve Replacement Outcomes. JACC Cardiovascular Interventions 2020, 13: 335-343. PMID: 32029250, PMCID: PMC8858441, DOI: 10.1016/j.jcin.2019.09.048.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveClinical CompetenceDatabases, FactualFemaleHeart Valve Prosthesis ImplantationHospitals, High-VolumeHospitals, Low-VolumeHumansMaleMedicareOutcome and Process Assessment, Health CareQuality Indicators, Health CareRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementSurgical aortic valve replacementTranscatheter aortic valve replacement outcomesAortic valve replacementValve replacementConcomitant coronary artery bypass graft surgeryGroup 2Aortic valve replacement volumesGroup 1Group 3Group 4Surgical aortic valve replacement volumeCoronary artery bypass graft surgeryTranscatheter aortic valve replacement procedureArtery bypass graft surgeryAortic valve replacement proceduresYear post-procedureOpen-heart proceduresRisk-adjusted odds ratioMultivariate Cox regressionHeart valve proceduresLow-volume centersValve replacement proceduresTAVR admissionsBypass graft surgeryThirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery
Hirji SA, Percy ED, Zogg CK, Vaduganathan M, Kiehm S, Pelletier M, Kaneko T. Thirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery. The Annals Of Thoracic Surgery 2020, 110: 484-491. PMID: 31972128, PMCID: PMC7382395, DOI: 10.1016/j.athoracsur.2019.11.042.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementNonindex readmissionsCardiac surgeryNonindex hospitalNonindex hospital readmissionsCoronary artery bypassNational Readmission DatabaseAortic valve replacementCardiac surgery patientsMajor cardiac surgeryPatient risk profileHigh-volume centersUS adult patientsRegionalization of careFragmentation of careComorbidity burdenHospital mortalityIndex readmissionArtery bypassInitial hospitalizationAdult patientsSurgery patientsValve replacementHospital readmissionIndependent predictors
2019
Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Kolkailah A, Doukky R, Pelletier M, Volgman A, Kaneko T, Nabhan A. Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk. Cochrane Database Of Systematic Reviews 2019, 12: cd013319. PMID: 31860123, PMCID: PMC6984621, DOI: 10.1002/14651858.cd013319.pub2.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementLength of hospital stayLow surgical riskAortic valve replacementTranscatheter aortic valve implantationAcute kidney injuryRisk of PPM implantationRisk of atrial fibrillationSurgical riskAortic valve stenosisRandomised controlled trialsValve replacementAortic valve implantationAtrial fibrillationCardiac deathCertainty of evidenceMyocardial infarctionPPM implantationPermanent pacemakerValve implantationAssociated with shorter lengths of hospital stayNew-onset atrial fibrillationRisk ratioLong-term follow-up dataShorter length of hospital stayInequity in Access to Transcatheter Aortic Valve Replacement: A Pan-Canadian Evaluation of Wait-Times
Wijeysundera H, Henning K, Qiu F, Adams C, Al Qoofi F, Asgar A, Austin P, Bainey K, Cohen E, Daneault B, Fremes S, Kass M, Ko D, Lambert L, Lauck S, MacFarlane K, Nadeem S, Oakes G, Paddock V, Pelletier M, Peterson M, Piazza N, Potter B, Radhakrishnan S, Rodes-Cabau J, Toleva O, Webb J, Welsh R, Wood D, Woodward G, Zimmermann R. Inequity in Access to Transcatheter Aortic Valve Replacement: A Pan-Canadian Evaluation of Wait-Times. Canadian Journal Of Cardiology 2019, 36: 844-851. PMID: 32349882, DOI: 10.1016/j.cjca.2019.10.018.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementTranscatheter aortic valve replacement procedureAortic valve replacementValve replacementHazard ratioMedian hazard ratioTranscatheter aortic valve replacement casesCox proportional hazards modelsMedian wait-timeTAVR accessProportional hazards modelWait-timeIdentical patientsHazards modelMultilevel Cox proportional hazards modelsEffect of provincesTranscatheterYear increaseCardiac Surgery in Patients With Opioid Use Disorder: An Analysis of 1.7 Million Surgeries
Shah R, Hirji S, Percy E, Landino S, Yazdchi F, Bellavia A, Pelletier M, Shekar P, Kaneko T. Cardiac Surgery in Patients With Opioid Use Disorder: An Analysis of 1.7 Million Surgeries. The Annals Of Thoracic Surgery 2019, 109: 1194-1201. PMID: 31479643, DOI: 10.1016/j.athoracsur.2019.07.041.Peer-Reviewed Original ResearchConceptsOpioid use disorderCardiac surgeryIncreased risk of postoperative morbidityImpact of opioid use disorderRisk of postoperative morbidityOpioid epidemicAssociated with prolonged hospitalizationRisk factorsUse disorderOpioid use disorder statusCoronary artery bypass graftingNon-opioid usersPreoperative risk factorsCardiac surgery patientsPatient's preoperative risk factorsAcute kidney injuryArtery bypass graftingCardiac surgery outcomesIn-hospital mortalityCurrent opioid epidemicLonger hospital lengthImprove overall outcomesHigher hospital costsNational Inpatient SampleValve repairSignificance of Interstitial Lung Disease on Outcomes Following Cardiac Surgery
Hirji S, Ramirez-Del Val F, Ejiofor J, Lee J, Norman A, McGurk S, Pelletier M, Aranki S, Rawn J, Shekar P, Hunninghake G, Kaneko T. Significance of Interstitial Lung Disease on Outcomes Following Cardiac Surgery. The American Journal Of Cardiology 2019, 124: 1133-1139. PMID: 31405546, DOI: 10.1016/j.amjcard.2019.06.031.Peer-Reviewed Original ResearchConceptsInterstitial lung diseaseInterstitial lung disease patientsIdiopathic pulmonary fibrosisLong-term survivalLonger intensive care unitCardiac surgeryNon-ILD patientsIntensive care unitReintubation rateAssociated with shorter long-term survivalLung diseaseComparison cohortSeverity of interstitial lung diseaseShorter long-term survivalCare unitKaplan-Meier estimates of survivalIdiopathic pulmonary fibrosis cohortsRisk factorsInterstitial lung disease diagnosisSurvival analysisAcute pulmonary exacerbationsIncreased operative mortalityMedian follow-upCardiac surgery patientsRisk-adjusted survival analysis
2017
Impact of flow, gradient, and left ventricular function on outcomes after transcatheter aortic valve replacement
Carreras E, Kaneko T, Val F, Pelletier M, Sobieszczyk P, Bhatt D, Shah P. Impact of flow, gradient, and left ventricular function on outcomes after transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2017, 91: 798-805. PMID: 28988432, PMCID: PMC5849510, DOI: 10.1002/ccd.27347.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBostonFemaleHeart FailureHospital MortalityHumansLength of StayMaleRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexStroke VolumeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeVentricular Dysfunction, LeftVentricular Function, LeftConceptsTranscatheter aortic valve replacementAortic valve replacementStroke volume indexHeart failureReduced LVEFValve replacementIncreased mortalityOutcomes similar to patientsTranscatheter aortic valve replacement patientsPredictor of 1-year mortalityAssociated with increased mortalityOutcomes of patientsLeft ventricular functionSimilar to patientsReduced EFVentricular functionLVEFClinical factorsWomen's HospitalVolume indexPatientsAssociated with increasesMortalityTranscatheterOutcomesAspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomized Clinical Trial
Rodés-Cabau J, Masson J, Welsh R, del Blanco B, Pelletier M, Webb J, Al-Qoofi F, Généreux P, Maluenda G, Thoenes M, Paradis J, Chamandi C, Serra V, Dumont E, Côté M. Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve The ARTE (Aspirin Versus Aspirin + Clopidogrel Following Transcatheter Aortic Valve Implantation) Randomized Clinical Trial. JACC Cardiovascular Interventions 2017, 10: 1357-1365. PMID: 28527771, DOI: 10.1016/j.jcin.2017.04.014.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAspirinBalloon ValvuloplastyCanadaClopidogrelDrug Therapy, CombinationEarly Termination of Clinical TrialsEuropeFemaleFibrinolytic AgentsHeart Valve ProsthesisHemorrhageHumansIschemic Attack, TransientKaplan-Meier EstimateMaleMyocardial InfarctionPlatelet Aggregation InhibitorsProsthesis DesignRisk FactorsSouth AmericaStrokeThrombosisTiclopidineTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsTranscatheter aortic valve replacementTransient ischemic attackLife-threatening bleedingAortic valve replacementBalloon-expandable valveOccurrence of deathMyocardial infarctionIschemic attackBleeding eventsValve replacementAntithrombotic treatmentClinical trialsLife-threatening bleeding eventsPrevention of ischemic eventsOptimal antithrombotic therapyComposite of deathRandomized clinical trialsPlanned study populationLife-threatening eventsRandomized controlled trialsCompared aspirinPrimary endpointAntithrombotic therapyPost-TAVRAdverse eventsTranscatheter aortic valve replacement with the Portico valve: one-year results of the early Canadian experience.
Perlman G, Cheung A, Dumont E, Stub D, Dvir D, Del Trigo M, Pelletier M, Alnasser S, Ye J, Wood D, Thompson C, Blanke P, Leipsic J, Seidman M, LeBlanc H, Buller C, Rodés-Cabau J, Webb J. Transcatheter aortic valve replacement with the Portico valve: one-year results of the early Canadian experience. EuroIntervention 2017, 12: 1653-1659. PMID: 28105999, DOI: 10.4244/eij-d-16-00299.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementPortico valveOutcomes of transcatheter aortic valve replacementFirst-in-human experienceSociety of Thoracic SurgeonsModerate/severe aortic regurgitationMedium-term outcomesOne-year resultsRisk of mortalityYears of ageAortic regurgitationEchocardiographic findingsThoracic surgeonsClinical resultsClinical reviewPatientsSelf-expandingEchocardiographyTranscatheterValveDaysRegurgitationShort-
2014
Variation in transfusion rates within a single institution: Exploring the effect of differing practice patterns on the likelihood of blood product transfusion in patients undergoing cardiac surgery
Cote C, MacLeod J, Yip A, Ouzounian M, Brown C, Forgie R, Pelletier M, Hassan A. Variation in transfusion rates within a single institution: Exploring the effect of differing practice patterns on the likelihood of blood product transfusion in patients undergoing cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2014, 149: 297-302. PMID: 25300883, DOI: 10.1016/j.jtcvs.2014.09.004.Peer-Reviewed Original ResearchConceptsRate of perioperative transfusionPerioperative transfusion ratesPerioperative transfusionTransfusion rateCardiac surgeryPractice patternsIntraoperative variablesPredictors of perioperative transfusionPredictors of blood transfusionOverall transfusion rateBlood product transfusionRisk-adjusted effectYear of procedureProduct transfusionBlood transfusionClinical predictorsIndependent predictorsClinical characteristicsClinical factorsTransfusionPatientsStudy populationSurgeryMultivariable regression modeling techniquesNonclinical factors
2003
Radial artery use is safe in patients with moderate to severe left ventricular dysfunction
Fazel S, Mallidi H, Pelletier M, Sever J, Christakis G, Goldman B, Fremes S. Radial artery use is safe in patients with moderate to severe left ventricular dysfunction. The Annals Of Thoracic Surgery 2003, 75: 1414-1421. PMID: 12735555, DOI: 10.1016/s0003-4975(02)04992-5.Peer-Reviewed Original ResearchConceptsModerate to severe left ventricular dysfunctionLeft ventricular dysfunctionSevere left ventricular dysfunctionRadial artery graftVentricular dysfunctionRadial artery useMyocardial infarctionAortocoronary bypassArterial graftsRate of deathPostoperative deathsArtery useLVD patientsRadial graftCohort analysisPredictive of deathMyocardial infarction rateLogistic regression analysisVasopressor supportIschemic complicationsGraft spasmLogistic regression modelsPatient subgroupsInfarction rateUnmatched group
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply