2024
Current Role of Cardiac Magnetic Resonance for the Clinical Decision-Making Process in Transcatheter Aortic Valve Replacement
Dallan L, Feroze R, Jarrett C, Yoon S, Rajagopalan V, Walker J, Baeza C, Pelletier M, Al-Kindi S, Ukaigwe A, Filby S, Rajagopalan S, Attizzani G, Rashid I. Current Role of Cardiac Magnetic Resonance for the Clinical Decision-Making Process in Transcatheter Aortic Valve Replacement. Cardiovascular Revascularization Medicine 2024, 65: 58. DOI: 10.1016/j.carrev.2024.04.130.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementAortic valve replacementCardiac magnetic resonanceValve replacementClinical decision-making processElevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement
Feroze R, Kang P, Dallan L, Akula N, Galo J, Yoon S, Ukaigwe A, Filby S, Baeza C, Pelletier M, Rushing G, Rajagopalan S, Al‐Kindi S, Rashid I, Attizzani G. Elevated myocardial extracellular volume fraction is associated with the development of conduction pathway defects following transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2024, 104: 1119-1128. PMID: 38952304, DOI: 10.1002/ccd.31136.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAgedAged, 80 and overAortic ValveAortic Valve StenosisArea Under CurveAtrioventricular BlockBundle-Branch BlockCardiac Pacing, ArtificialFemaleFibrosisHeart Conduction SystemHumansMagnetic Resonance Imaging, CineMaleMyocardiumPacemaker, ArtificialPredictive Value of TestsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsTranscatheter aortic valve replacementCardiac magnetic resonance imagingLate gadolinium enhancementRight bundle branch blockArea under the receiver operating characteristic curveAortic valve replacementReceiver operating curveMyocardial fibrosisPost-TAVRConduction defectsBundle branch blockAssociations of myocardial fibrosisExtracellular volumeConduction diseaseValve replacementGadolinium enhancementPermanent pacemakerConduction abnormalitiesConduction deficitsHeart blockBranch blockRisk of heart blockSeptal late gadolinium enhancementMyocardial extracellular volume fractionBaseline conduction disease400.13 Current Role of Cardiac Magnetic Resonance for the Clinical Decision-Making Process in Transcatheter Aortic Valve Replacement
Dallan L, Feroze R, Jarrett C, Yoon S, Rajagopalan V, Walker J, Baeza C, Pelletier M, Al-Kindi S, Ukaigwe A, Filby S, Rajagopalan S, Attizzani G, Rashid I. 400.13 Current Role of Cardiac Magnetic Resonance for the Clinical Decision-Making Process in Transcatheter Aortic Valve Replacement. JACC Cardiovascular Interventions 2024, 17: s46. DOI: 10.1016/j.jcin.2024.01.183.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementAortic valve replacementCardiac magnetic resonanceValve replacementClinical decision-making process
2023
Clinical impact of right ventricular pacing burden in patients with post-transcatheter aortic valve replacement permanent pacemaker implantation
Tsushima T, Al-Kindi S, Dallan L, Fares A, Yoon S, Wheat H, Attizzani G, Baeza C, Pelletier M, Arruda M, Mackall J, Thal S. Clinical impact of right ventricular pacing burden in patients with post-transcatheter aortic valve replacement permanent pacemaker implantation. EP Europace 2023, 25: 1441-1450. PMID: 36794441, PMCID: PMC10105841, DOI: 10.1093/europace/euad025.Peer-Reviewed Original ResearchConceptsRight ventricular pacing burdenTranscatheter aortic valve replacementVentricular pacing burdenPermanent pacemaker implantationPermanent pacemakerHeart failurePacing burdenPPM implantationRetrospective study of consecutive patientsLikelihood of heart failureStudy of consecutive patientsLeft ventricular ejection fractionAssociated with worse outcomesVentricular ejection fractionAortic valve replacementAtrial fibrillation burdenValve implantation depthConsecutive patientsEjection fractionValve replacementPost-TAVRClinical benefitPacemaker implantationRetrospective studySingle-centre
2021
B-PO02-039 CLINICAL IMPACT OF RIGHT VENTRICULAR PACING BURDEN IN PATIENTS WITH NEWLY IMPLANTED PACEMAKER AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT: SINGLE HIGH VOLUME CENTER EXPERIENCE
Tsushima T, Al-Kindi S, Wheat H, Fares A, Attizzani G, Baeza C, Pelletier M, Arruda M, Mackall J, Thal S. B-PO02-039 CLINICAL IMPACT OF RIGHT VENTRICULAR PACING BURDEN IN PATIENTS WITH NEWLY IMPLANTED PACEMAKER AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT: SINGLE HIGH VOLUME CENTER EXPERIENCE. Heart Rhythm 2021, 18: s111. DOI: 10.1016/j.hrthm.2021.06.295.Peer-Reviewed Original ResearchRight ventricular pacing burdenTranscatheter aortic valve replacementVentricular pacing burdenAortic valve replacementPacing burdenValve replacementCenter's experienceImplanted pacemaker
2020
TCT CONNECT-87 Redo Transcatheter Aortic Valve Replacement With the Supra-Annular, Self-Expandable Evolut Platform: Insights From the TVT Registry
Attizzani G, Dallan L, Pelletier M, Deeb G, Forrest J, Reardon M, Popma J. TCT CONNECT-87 Redo Transcatheter Aortic Valve Replacement With the Supra-Annular, Self-Expandable Evolut Platform: Insights From the TVT Registry. Journal Of The American College Of Cardiology 2020, 76: b38-b39. DOI: 10.1016/j.jacc.2020.09.101.Peer-Reviewed Original ResearchRedo transcatheter aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementTVT RegistryValve replacementRegistryThe Sky Is Not Falling: Surgical Perspectives on a New Transcatheter Paradigm
Percy E, Hirji S, Yazdchi F, Pelletier M. The Sky Is Not Falling: Surgical Perspectives on a New Transcatheter Paradigm. Canadian Journal Of Cardiology 2020, 37: 22-26. PMID: 32649869, DOI: 10.1016/j.cjca.2020.03.016.Peer-Reviewed Original ResearchConceptsCardiac surgeonsTranscatheter aortic valve replacement trialsTreatment of aortic valve diseaseTranscatheter aortic valve replacementCardiac surgery communityLow surgical riskAortic valve replacementCardiac surgical communityAortic valve diseaseExpansion of transcatheter aortic valve replacementSurgical riskValve replacementHeart teamValve diseaseSurgical perspectiveReplacement trialsSurgery communitySurgical communityOperative volumeSurgeonsHeart medicineTrialsSurgicallyPatientsPERIPHERAL VERSUS CENTRAL ACCESS FOR ALTERNATIVE ACCESS TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR): RESULTS FROM THE TVT REGISTRY
Kaneko T, Yazdchi F, Hirji S, Pelletier M, Sobieszczyk P, Nyman C, Shook D, Sun Y, Kim A, Cohen D, Stebbins A, Zeitouni M, Vemulapalli S, Thourani V, Shah P, O'Gara P. PERIPHERAL VERSUS CENTRAL ACCESS FOR ALTERNATIVE ACCESS TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR): RESULTS FROM THE TVT REGISTRY. Journal Of The American College Of Cardiology 2020, 75: 1177. DOI: 10.1016/s0735-1097(20)31804-0.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementAlternative access transcatheter aortic valve replacementAortic valve replacementValve replacementUtility of 90-Day Mortality vs 30-Day Mortality as a Quality Metric for Transcatheter and Surgical Aortic Valve Replacement Outcomes
Hirji S, McGurk S, Kiehm S, Ejiofor J, Val F, Kolkailah A, Berry N, Sobieszczyk P, Pelletier M, Shah P, O’Gara P, Kaneko T. Utility of 90-Day Mortality vs 30-Day Mortality as a Quality Metric for Transcatheter and Surgical Aortic Valve Replacement Outcomes. JAMA Cardiology 2020, 5: 156-165. PMID: 31851293, PMCID: PMC6990722, DOI: 10.1001/jamacardio.2019.4657.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementSurgical aortic valve replacement proceduresAortic valve replacementHospital performanceEvaluation of hospital performanceValve replacementHospital performance rankingsCohort study analyzed dataMeasure hospital performanceConcomitant coronary artery bypass graftingCoronary artery bypass graftingProcedure-related mortalityOpen-heart proceduresStudy analyzed dataPatient risk profileSurgical aortic valve replacement outcomesTAVR admissionsArtery bypass graftingMedicare beneficiariesMain OutcomesReplacement outcomesOutcome metricsRisk adjustmentBypass graftingRelationship Between Hospital Surgical Aortic Valve Replacement Volume and Transcatheter Aortic Valve Replacement Outcomes
Hirji S, McCarthy E, Kim D, McGurk S, Ejiofor J, Val F, Kolkailah A, Rosner B, Shook D, Nyman C, Berry N, Sobieszczyk P, Pelletier M, Shah P, O’Gara P, Kaneko T. Relationship Between Hospital Surgical Aortic Valve Replacement Volume and Transcatheter Aortic Valve Replacement Outcomes. JACC Cardiovascular Interventions 2020, 13: 335-343. PMID: 32029250, PMCID: PMC8858441, DOI: 10.1016/j.jcin.2019.09.048.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveClinical CompetenceDatabases, FactualFemaleHeart Valve Prosthesis ImplantationHospitals, High-VolumeHospitals, Low-VolumeHumansMaleMedicareOutcome and Process Assessment, Health CareQuality Indicators, Health CareRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementSurgical aortic valve replacementTranscatheter aortic valve replacement outcomesAortic valve replacementValve replacementConcomitant coronary artery bypass graft surgeryGroup 2Aortic valve replacement volumesGroup 1Group 3Group 4Surgical aortic valve replacement volumeCoronary artery bypass graft surgeryTranscatheter aortic valve replacement procedureArtery bypass graft surgeryAortic valve replacement proceduresYear post-procedureOpen-heart proceduresRisk-adjusted odds ratioMultivariate Cox regressionHeart valve proceduresLow-volume centersValve replacement proceduresTAVR admissionsBypass graft surgeryTranscatheter vs surgical aortic valve replacement in patients with interstitial lung disease
Hirji S, Cote C, Lee J, Kiehm S, McGurk S, Pelletier M, Aranki S, Shekar P, Shah P, Kaneko T. Transcatheter vs surgical aortic valve replacement in patients with interstitial lung disease. Journal Of Cardiac Surgery 2020, 35: 571-579. PMID: 31981435, DOI: 10.1111/jocs.14421.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementInterstitial lung diseaseAortic valve replacementTranscatheter aortic valve replacement patientsIntensive care unitSurgical aortic valve replacement patientsInterstitial lung disease patientsShorter ventilation timeValve replacementOperative mortalityAortic stenosisVentilation timeLung diseaseRisk of postoperative pulmonary complicationsIsolated surgical aortic valve replacementDiagnosis of interstitial lung diseaseAssociated with significantly shorter hospitalRate of postoperative strokeIntensive care unit admissionPostoperative pulmonary complicationsSignificantly shorter hospitalSevere aortic stenosisPermanent pacemaker implantationSymptomatic aortic stenosis
2019
Inequity in Access to Transcatheter Aortic Valve Replacement: A Pan-Canadian Evaluation of Wait-Times
Wijeysundera H, Henning K, Qiu F, Adams C, Al Qoofi F, Asgar A, Austin P, Bainey K, Cohen E, Daneault B, Fremes S, Kass M, Ko D, Lambert L, Lauck S, MacFarlane K, Nadeem S, Oakes G, Paddock V, Pelletier M, Peterson M, Piazza N, Potter B, Radhakrishnan S, Rodes-Cabau J, Toleva O, Webb J, Welsh R, Wood D, Woodward G, Zimmermann R. Inequity in Access to Transcatheter Aortic Valve Replacement: A Pan-Canadian Evaluation of Wait-Times. Canadian Journal Of Cardiology 2019, 36: 844-851. PMID: 32349882, DOI: 10.1016/j.cjca.2019.10.018.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementTranscatheter aortic valve replacement procedureAortic valve replacementValve replacementHazard ratioMedian hazard ratioTranscatheter aortic valve replacement casesCox proportional hazards modelsMedian wait-timeTAVR accessProportional hazards modelWait-timeIdentical patientsHazards modelMultilevel Cox proportional hazards modelsEffect of provincesTranscatheterYear increase
2018
Minimally invasive versus full sternotomy aortic valve replacement in low-risk patients: Which will stand against transcatheter aortic valve replacement?
Hirji S, Funamoto M, Lee J, Ramirez Del Val F, Kolkailah A, McGurk S, Pelletier M, Aranki S, Shekar P, Kaneko T. Minimally invasive versus full sternotomy aortic valve replacement in low-risk patients: Which will stand against transcatheter aortic valve replacement? Surgery 2018, 164: 282-287. PMID: 29699805, DOI: 10.1016/j.surg.2018.02.018.Peer-Reviewed Original ResearchConceptsMinimally invasive aortic valve replacementAortic valve replacement patientsAortic valve replacementLow-risk patientsMinimally invasive aortic valve replacement patientsValve replacement patientsSternotomy aortic valve replacementIntensive care unitTranscatheter aortic valve replacementValve replacementCongestive heart failureCare unitReoperation rateHeart failureElective isolated aortic valve replacementHospital lengthReplacement patientsAortic valve replacement resultsMedian intensive care unitShorter intensive care unitPredictors of decreased survivalShorter median intensive care unitValve replacement resultsAssociated with improved resultsPredicted risk of mortalityTranscatheter Aortic Valve Replacement after Transcatheter Mitral Valve Replacement
Kaneko T, Pelletier M, Berry N, Sobieszczyk P, Shah P. Transcatheter Aortic Valve Replacement after Transcatheter Mitral Valve Replacement. Structural Heart 2018, 2: 164-168. DOI: 10.1080/24748706.2017.1422086.Peer-Reviewed Original ResearchTranscatheter mitral valve replacementTranscatheter aortic valve replacementLeft ventricular outflow tractMitral valve replacementAortic valve replacementValve replacementAortic stenosisSimultaneous transcatheter aortic valve replacementVentricular outflow tractSevere aortic stenosisMitral annular calcificationSymptomatic aortic stenosisBalloon-expandable valveSelf-expanding valveOutflow tractAnnular calcificationTranscatheter valvesDeteriorated prosthesesTranscatheterPatientsValve selectionStenosisValve frameBalloonValveNovel fast-track recovery protocol for alternative access transcatheter aortic valve replacement: application to non-femoral approaches
Kolkailah A, Hirji S, Ejiofor J, Del Val F, Lee J, Norman A, McGurk S, Mahmood S, Shook D, Vlassakov K, Nyman C, Shah P, Pelletier M, Kaneko T. Novel fast-track recovery protocol for alternative access transcatheter aortic valve replacement: application to non-femoral approaches. Interdisciplinary CardioVascular And Thoracic Surgery 2018, 26: 938-943. PMID: 29365108, DOI: 10.1093/icvts/ivx409.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementPre-fast-trackAortic valve replacementAlternative access transcatheter aortic valve replacementValve replacementIntensive care unitFT protocolCare unitShorter intensive care unitMultidisciplinary heart team approachIntensive care unit timeFast-track (FTFast-track recovery protocolTranscatheter aortic valve replacement utilizationHeart team approachEnhance patient recoveryComparison of outcomesIncreased procedural complicationsFT patientsProcedural complicationsTranscatheterPatientsTransfemoral approachIliofemoral vesselsPatient recoveryClinical Significance of Greater Implantation Height with SAPIEN 3 Transcatheter Heart Valve.
Ramirez Del Val F, Hirji S, Carreras E, Kolkailah A, Chowdhury R, McGurk S, Lee J, Nyman C, Shook D, Sobieszczyk P, Pelletier M, Shah P, Kaneko T. Clinical Significance of Greater Implantation Height with SAPIEN 3 Transcatheter Heart Valve. The Journal Of Heart Valve Disease 2018, 27: 9-16. PMID: 30560594.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementRight bundle branch blockPreoperative right bundle branch blockPermanent pacemaker implantationRate of PPM implantationSAPIEN 3 valvePermanent pacemakerPPM implantationOperative mortalityHigher implantationHI patientsSociety of Thoracic Surgeons Predicted RiskClinical significanceAssociated with PPM implantationImplant heightTranscatheter aortic valve replacement patientsThoracic Surgeons Predicted RiskRates of permanent pacemakerStandard implantsIncreased operative mortalityAortic valve replacementLong-term followTranscatheter heart valveBundle branch blockValve replacement
2017
Impact of flow, gradient, and left ventricular function on outcomes after transcatheter aortic valve replacement
Carreras E, Kaneko T, Val F, Pelletier M, Sobieszczyk P, Bhatt D, Shah P. Impact of flow, gradient, and left ventricular function on outcomes after transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2017, 91: 798-805. PMID: 28988432, PMCID: PMC5849510, DOI: 10.1002/ccd.27347.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBostonFemaleHeart FailureHospital MortalityHumansLength of StayMaleRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexStroke VolumeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeVentricular Dysfunction, LeftVentricular Function, LeftConceptsTranscatheter aortic valve replacementAortic valve replacementStroke volume indexHeart failureReduced LVEFValve replacementIncreased mortalityOutcomes similar to patientsTranscatheter aortic valve replacement patientsPredictor of 1-year mortalityAssociated with increased mortalityOutcomes of patientsLeft ventricular functionSimilar to patientsReduced EFVentricular functionLVEFClinical factorsWomen's HospitalVolume indexPatientsAssociated with increasesMortalityTranscatheterOutcomesOutcomes of surgical and transcatheter aortic valve replacement in the octogenarians-surgery still the gold standard?
Hirji S, Ramirez-Del Val F, Kolkailah A, Ejiofor J, McGurk S, Chowdhury R, Lee J, Shah P, Sobieszczyk P, Aranki S, Pelletier M, Shekar P, Kaneko T. Outcomes of surgical and transcatheter aortic valve replacement in the octogenarians-surgery still the gold standard? Annals Of Cardiothoracic Surgery 2017, 6: 453-462. PMID: 29062740, PMCID: PMC5639227, DOI: 10.21037/acs.2017.08.01.Peer-Reviewed Original ResearchMinimally invasive AVRAortic valve replacementNew York Heart AssociationMid-term survivalOperative mortalityChronic kidney diseaseSAVR groupValve replacementDiabetes mellitusIsolated aortic valve replacementPredictors of decreased survivalMyocardial infarctionSevere chronic lung diseaseTranscatheter aortic valve replacementMedian follow-upIntermediate risk patientsOverall operative mortalityIn-hospital LOSMulti-disciplinary heart teamCerebrovascular diseaseChronic lung diseaseCox proportional hazards modelsProportional hazards modelPreoperative creatinineCardiac surgeryReply Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve
Rodés-Cabau J, Masson J, Welsh R, del Blanco B, Pelletier M, Webb J, Al-Qoofi F, Généreux P, Maluenda G, Thoenes M, Paradis J, Chamandi C, Serra V, Dumont E, Côté M. Reply Aspirin Versus Aspirin Plus Clopidogrel as Antithrombotic Treatment Following Transcatheter Aortic Valve Replacement With a Balloon-Expandable Valve. JACC Cardiovascular Interventions 2017, 10: 1599-1600. PMID: 28797439, DOI: 10.1016/j.jcin.2017.06.052.Peer-Reviewed Original Research“Double-Stick” Transsubclavian Transcatheter Aortic Valve Replacement With Use of a Balloon Expandable Valve: A Less Invasive Option for Alternative Access
Jarrett C, Pelletier M, Shah P, Kaneko T. “Double-Stick” Transsubclavian Transcatheter Aortic Valve Replacement With Use of a Balloon Expandable Valve: A Less Invasive Option for Alternative Access. The Annals Of Thoracic Surgery 2017, 104: e195-e197. PMID: 28734453, DOI: 10.1016/j.athoracsur.2017.02.064.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementBalloon-expandable valveValve replacementArterial accessTranssubclavian approachPigtail catheter placementSecondary arterial accessRadial artery accessInvasive optionCatheter placementRapid ambulationPeripheral accessTransfemoral access
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