2024
Pericardial fluid troponin in cardiac surgery
Fatehi Hassanabad A, El-Sherbini A, Cherif I, Ahmad B, Gonzalez A, Pelletier M, Fedak P, El-Diasty M. Pericardial fluid troponin in cardiac surgery. Clinica Chimica Acta 2024, 559: 119722. PMID: 38734224, DOI: 10.1016/j.cca.2024.119722.Peer-Reviewed Original ResearchConceptsCardiac surgeryPericardial fluidTroponin levelsLevels of cardiac troponinPF levelsCardiac troponin levelsTroponin changesGoogle Scholar databasesTroponin concentrationsCardiac troponinProcedure typeClinical significancePrimary outcomeSurgerySecondary outcomesBiologically active factorsBlinded reviewersPreferred Reporting ItemsFull-text reviewTroponinInclusion criteriaPatientsPathological changesScholar databasesSystematic review
2023
Outcomes of Status 4 Heart Transplant Candidates: A Nationwide Analysis
Jarrett C, Mahmoud O, Abu-Omar Y, Elgudin Y, Hussian O, Pelletier M, Sabik J, ElAmm C. Outcomes of Status 4 Heart Transplant Candidates: A Nationwide Analysis. The Journal Of Heart And Lung Transplantation 2023, 42: s282. DOI: 10.1016/j.healun.2023.02.643.Peer-Reviewed Original ResearchStatus 4Re-transplantWaitlist survivalHeart diseaseTwo-thirds of patientsCongenital heart diseaseKaplan-Meier methodLog-rank testInotrope-dependent patientsHeart transplant candidatesIschemic heart diseaseNationwide analysisInotrope dependencePrimary endpointIschemic cardiomyopathyHeart transplantationIV inotropesTransplantationUnique patientsTransplant candidatesInotropesPatientsSurvivalCardiomyopathyMonthsThe Fate of Status 6 Heart Transplant Candidates: A Nationwide Analysis
Jarrett C, Mahmoud O, Elgudin Y, Hussian O, Pelletier M, Sabik J, ElAmm C, Abu-Omar Y. The Fate of Status 6 Heart Transplant Candidates: A Nationwide Analysis. The Journal Of Heart And Lung Transplantation 2023, 42: s282. DOI: 10.1016/j.healun.2023.02.644.Peer-Reviewed Original ResearchHeart transplant candidatesTransplant candidatesTwo-thirds of patientsMedian follow-upKaplan-Meier methodLog-rank testAdvanced heart failureNationwide analysisPrimary endpointMedian ageHeart transplantationHeart failureFollow-upUnique patientsPatientsTransplantationMonthsSurvivalHeartTwo-thirdsStatusSTAR filesYears
2022
Risk Stratification of New Persistent Left Bundle Branch Block After Transcatheter Aortic Valve Implantation
Tsushima T, Main A, Al-Kindi S, Dallan L, Wheat H, Baeza C, Pelletier M, Arruda M, Mackall J, Thal S, Ohno Y, Lee K, Siqueira D, Kaneko T, Harloff M, Costa G, Barbanti M, Attizzani G. Risk Stratification of New Persistent Left Bundle Branch Block After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2022, 175: 80-87. PMID: 35597627, DOI: 10.1016/j.amjcard.2022.03.053.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionTranscatheter aortic valve implantationPersistent left bundle branch blockAssociated with cardiac mortalityNOP-LBBBLeft bundle branch blockLong-term outcomesBundle branch blockAortic valve implantationCardiac mortalityRisk stratificationComposite outcomeNew-onset persistent left bundle branch blockBranch blockValve implantationRetrospective study of patientsVentricular ejection fractionStudy of patientsHeart failure readmissionEjection fractionPermanent pacemakerRetrospective studyHeart failurePost-TAVIPatients
2021
Redo‐transcatheter aortic valve replacement with the supra‐annular, self‐expandable Evolut platform: Insights from the Transcatheter valve Therapy Registry
Attizzani GF, Dallan LAP, Forrest JK, Reardon MJ, Szeto WY, Liu F, Pelletier M. Redo‐transcatheter aortic valve replacement with the supra‐annular, self‐expandable Evolut platform: Insights from the Transcatheter valve Therapy Registry. Catheterization And Cardiovascular Interventions 2021, 99: 869-876. PMID: 34533891, DOI: 10.1002/ccd.29941.Peer-Reviewed Original ResearchConceptsTranscatheter Valve Therapy RegistryTranscatheter aortic valveRedo-TAVRTVT RegistryRedo transcatheter aortic valve replacementBetter short-term outcomesTotal aortic regurgitationAortic valve replacementLow-risk patientsShort-term outcomesHospital mortalityIndex hospitalizationAortic regurgitationValve replacementDevice successEvolut RSafety profileMyocardial infarctionAortic valveEvolut PROPatientsRegistryMean gradientOutcomesEvolut
2020
Safety‐net hospitals versus non‐safety centers and clinical outcomes after trans‐catheter aortic valve replacement
Sheikh M, Deo S, Riaz H, Raza S, Altarabsheh S, Wilson B, Elgudin Y, Cmolik B, Pelletier M, Markowitz A. Safety‐net hospitals versus non‐safety centers and clinical outcomes after trans‐catheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2020, 97: e425-e430. PMID: 32681697, DOI: 10.1002/ccd.29123.Peer-Reviewed Original ResearchConceptsValve replacementNational in-patient sampleLength of post-operative stayPropensity-matched cohort of patientsTrans-catheter aortic valve replacementPost-operative stayAortic valve replacementClinical co-variatesCohort of patientsAcute kidney injuryPropensity-matched cohortPost-procedural mortalityPost-procedural outcomesClinical outcomesKidney injurySecondary outcomesIn-patient samplePatientsLow-income patientsSafety-net hospitalHospitalOutcomesSafety-netIncome patientsNon-safety net hospitalsThe Sky Is Not Falling: Surgical Perspectives on a New Transcatheter Paradigm
Percy E, Hirji S, Yazdchi F, Pelletier M. The Sky Is Not Falling: Surgical Perspectives on a New Transcatheter Paradigm. Canadian Journal Of Cardiology 2020, 37: 22-26. PMID: 32649869, DOI: 10.1016/j.cjca.2020.03.016.Peer-Reviewed Original ResearchConceptsCardiac surgeonsTranscatheter aortic valve replacement trialsTreatment of aortic valve diseaseTranscatheter aortic valve replacementCardiac surgery communityLow surgical riskAortic valve replacementCardiac surgical communityAortic valve diseaseExpansion of transcatheter aortic valve replacementSurgical riskValve replacementHeart teamValve diseaseSurgical perspectiveReplacement trialsSurgery communitySurgical communityOperative volumeSurgeonsHeart medicineTrialsSurgicallyPatients
2019
Chronic opioid use after coronary bypass surgery
Hirji S, Landino S, Cote C, Lee J, Orhurhu V, Shah R, McGurk S, Kaneko T, Shekar P, Pelletier M. Chronic opioid use after coronary bypass surgery. Journal Of Cardiac Surgery 2019, 34: 67-73. PMID: 30625257, DOI: 10.1111/jocs.13981.Peer-Reviewed Original ResearchConceptsOpioid-exposed patientsCoronary artery bypass graftingOpioid naive patientsChronic opioid useChronic opioid dependenceOpioid dependencePrescribing patternsOpioid useIsolated coronary artery bypass graftingAlternative pain management strategiesTotal dose >Opioid prescribing patternsPain management strategiesArtery bypass graftingCoronary bypass surgeryInvasive surgical proceduresOpioid usageBypass surgeryPain managementBypass graftingSurgical proceduresOpioidOpioid epidemicPatientsMedication usage
2018
Transcatheter Aortic Valve Replacement after Transcatheter Mitral Valve Replacement
Kaneko T, Pelletier M, Berry N, Sobieszczyk P, Shah P. Transcatheter Aortic Valve Replacement after Transcatheter Mitral Valve Replacement. Structural Heart 2018, 2: 164-168. DOI: 10.1080/24748706.2017.1422086.Peer-Reviewed Original ResearchTranscatheter mitral valve replacementTranscatheter aortic valve replacementLeft ventricular outflow tractMitral valve replacementAortic valve replacementValve replacementAortic stenosisSimultaneous transcatheter aortic valve replacementVentricular outflow tractSevere aortic stenosisMitral annular calcificationSymptomatic aortic stenosisBalloon-expandable valveSelf-expanding valveOutflow tractAnnular calcificationTranscatheter valvesDeteriorated prosthesesTranscatheterPatientsValve selectionStenosisValve frameBalloonValveNovel fast-track recovery protocol for alternative access transcatheter aortic valve replacement: application to non-femoral approaches
Kolkailah A, Hirji S, Ejiofor J, Del Val F, Lee J, Norman A, McGurk S, Mahmood S, Shook D, Vlassakov K, Nyman C, Shah P, Pelletier M, Kaneko T. Novel fast-track recovery protocol for alternative access transcatheter aortic valve replacement: application to non-femoral approaches. Interdisciplinary CardioVascular And Thoracic Surgery 2018, 26: 938-943. PMID: 29365108, DOI: 10.1093/icvts/ivx409.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementPre-fast-trackAortic valve replacementAlternative access transcatheter aortic valve replacementValve replacementIntensive care unitFT protocolCare unitShorter intensive care unitMultidisciplinary heart team approachIntensive care unit timeFast-track (FTFast-track recovery protocolTranscatheter aortic valve replacement utilizationHeart team approachEnhance patient recoveryComparison of outcomesIncreased procedural complicationsFT patientsProcedural complicationsTranscatheterPatientsTransfemoral approachIliofemoral vesselsPatient recovery
2017
Impact of flow, gradient, and left ventricular function on outcomes after transcatheter aortic valve replacement
Carreras E, Kaneko T, Val F, Pelletier M, Sobieszczyk P, Bhatt D, Shah P. Impact of flow, gradient, and left ventricular function on outcomes after transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2017, 91: 798-805. PMID: 28988432, PMCID: PMC5849510, DOI: 10.1002/ccd.27347.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBostonFemaleHeart FailureHospital MortalityHumansLength of StayMaleRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexStroke VolumeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeVentricular Dysfunction, LeftVentricular Function, LeftConceptsTranscatheter aortic valve replacementAortic valve replacementStroke volume indexHeart failureReduced LVEFValve replacementIncreased mortalityOutcomes similar to patientsTranscatheter aortic valve replacement patientsPredictor of 1-year mortalityAssociated with increased mortalityOutcomes of patientsLeft ventricular functionSimilar to patientsReduced EFVentricular functionLVEFClinical factorsWomen's HospitalVolume indexPatientsAssociated with increasesMortalityTranscatheterOutcomesTranscatheter aortic valve replacement with the Portico valve: one-year results of the early Canadian experience.
Perlman G, Cheung A, Dumont E, Stub D, Dvir D, Del Trigo M, Pelletier M, Alnasser S, Ye J, Wood D, Thompson C, Blanke P, Leipsic J, Seidman M, LeBlanc H, Buller C, Rodés-Cabau J, Webb J. Transcatheter aortic valve replacement with the Portico valve: one-year results of the early Canadian experience. EuroIntervention 2017, 12: 1653-1659. PMID: 28105999, DOI: 10.4244/eij-d-16-00299.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementPortico valveOutcomes of transcatheter aortic valve replacementFirst-in-human experienceSociety of Thoracic SurgeonsModerate/severe aortic regurgitationMedium-term outcomesOne-year resultsRisk of mortalityYears of ageAortic regurgitationEchocardiographic findingsThoracic surgeonsClinical resultsClinical reviewPatientsSelf-expandingEchocardiographyTranscatheterValveDaysRegurgitationShort-
2016
Transapical Cannulation Through a Transcatheter Aortic Valve Implantation Valve: A Novel Approach for Cardiogenic Collapse
Tremblay L, Cote C, Pelletier M. Transapical Cannulation Through a Transcatheter Aortic Valve Implantation Valve: A Novel Approach for Cardiogenic Collapse. Seminars In Thoracic And Cardiovascular Surgery 2016, 28: 400-402. PMID: 28043451, DOI: 10.1053/j.semtcvs.2016.05.012.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic ValveAortic Valve StenosisBalloon ValvuloplastyCardiac CatheterizationCardiac Pacing, ArtificialCardiopulmonary BypassHeart Valve Prosthesis ImplantationHumansMalePeripheral Vascular DiseasesRadiography, InterventionalRecovery of FunctionSeverity of Illness IndexShockTreatment OutcomeVascular CalcificationConceptsCardiopulmonary bypassVentricular apexInitiation of cardiopulmonary bypassTranscatheter aortic valve implantation proceduresTranscatheter aortic-valve implantation valveLeft ventricular apexPatients' ventricular functionValve implantation proceduresPeripheral cannulationVentricular functionTranscatheter valvesCardiac functionProsthetic valvesImplanted valveImplantation procedureTransapical cannulationArterial cannulaCannulationTranscatheterPatientsBypass
2015
Increased Distance From the Tertiary Cardiac Center Is Associated With Worse 30-Day Outcomes After Cardiac Operations
Cote C, Singh S, Yip A, Murray J, MacLeod J, Lutchmedial S, Brown C, Forgie R, Pelletier M, Hassan A. Increased Distance From the Tertiary Cardiac Center Is Associated With Worse 30-Day Outcomes After Cardiac Operations. The Annals Of Thoracic Surgery 2015, 100: 2213-2218. PMID: 26271578, DOI: 10.1016/j.athoracsur.2015.05.058.Peer-Reviewed Original ResearchConceptsTertiary cardiac care centerCardiac operationsCardiac care centerIn-hospitalNonemergent cardiac operationsCare centerRisk of adverse outcomesEffect of driving distanceTertiary cardiac centerIn-hospital outcomesMultivariate logistic regressionCardiac centerRetrospective analysisFollow-upAdverse outcomesPatient groupPatientsStudy populationLogistic regressionCardiovascular carePatient's homeOutcomesResidents
2014
Variation in transfusion rates within a single institution: Exploring the effect of differing practice patterns on the likelihood of blood product transfusion in patients undergoing cardiac surgery
Cote C, MacLeod J, Yip A, Ouzounian M, Brown C, Forgie R, Pelletier M, Hassan A. Variation in transfusion rates within a single institution: Exploring the effect of differing practice patterns on the likelihood of blood product transfusion in patients undergoing cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2014, 149: 297-302. PMID: 25300883, DOI: 10.1016/j.jtcvs.2014.09.004.Peer-Reviewed Original ResearchConceptsRate of perioperative transfusionPerioperative transfusion ratesPerioperative transfusionTransfusion rateCardiac surgeryPractice patternsIntraoperative variablesPredictors of perioperative transfusionPredictors of blood transfusionOverall transfusion rateBlood product transfusionRisk-adjusted effectYear of procedureProduct transfusionBlood transfusionClinical predictorsIndependent predictorsClinical characteristicsClinical factorsTransfusionPatientsStudy populationSurgeryMultivariable regression modeling techniquesNonclinical factors
2012
505 The Effect of Brand of Heparin on Peri-Operative Transfusion Rates in Patients Undergoing Cardiac Surgery
Hassan A, Kang N, Yip A, Justason S, Ouzounian M, Lutchmedial S, O'Reilly B, Pelletier M. 505 The Effect of Brand of Heparin on Peri-Operative Transfusion Rates in Patients Undergoing Cardiac Surgery. Canadian Journal Of Cardiology 2012, 28: s285-s286. DOI: 10.1016/j.cjca.2012.07.461.Peer-Reviewed Original Research
2006
A randomized comparison of intraoperative indocyanine green angiography and transit-time flow measurement to detect technical errors in coronary bypass grafts
Desai N, Miwa S, Kodama D, Koyama T, Cohen G, Pelletier M, Cohen E, Christakis G, Goldman B, Fremes S. A randomized comparison of intraoperative indocyanine green angiography and transit-time flow measurement to detect technical errors in coronary bypass grafts. Journal Of Thoracic And Cardiovascular Surgery 2006, 132: 585-594. PMID: 16935114, DOI: 10.1016/j.jtcvs.2005.09.061.Peer-Reviewed Original ResearchConceptsIndocyanine green angiographyTransit-time flow measurementX-ray angiographyBypass graftingDiagnostic accuracyIsolated coronary artery bypass graftingIntraoperative indocyanine green angiographyUltrasound flow measurementsCoronary artery bypass graftingPostoperative day 4Artery bypass graftingCoronary bypass graftingGraft angiographyPostoperative angiographyBypass graft failureGraft failureGraft occlusionRandomized comparisonAngiographyPerianastomotic areaDetect technical errorsIndocyanineDay 4StenosisPatients
2005
Thoratec Ventricular Assist Devices in Pediatric Patients: Update on Clinical Results
Reinhartz O, Hill J, Al-Khaldi A, Pelletier M, Robbins R, Farrar D. Thoratec Ventricular Assist Devices in Pediatric Patients: Update on Clinical Results. ASAIO Journal 2005, 51: 501-503. PMID: 16322705, DOI: 10.1097/01.mat.0000178214.95010.c0.Peer-Reviewed Original ResearchConceptsThoratec ventricular assist deviceCongenital heart diseaseBody surface areaVentricular assist deviceAcute myocarditisHeart diseasePediatric patientsEnd-stage congenital heart diseaseIncidence of congenital heart diseaseOverall survival to transplantationMean body surface areaSurvival to transplantYears of ageMechanical circulatory supportClinical resultsClinical challengeAssist deviceSurvival ratePatientsCirculatory supportAverage durationSmall childrenMean weightThoratecCardiomyopathy
2003
Coronary atherosclerosis in cardiac transplant patients treated with total lymphoid irradiation
Pelletier M, Coady M, Macha M, Oyer P, Robbins R. Coronary atherosclerosis in cardiac transplant patients treated with total lymphoid irradiation. The Journal Of Heart And Lung Transplantation 2003, 22: 124-129. PMID: 12581759, DOI: 10.1016/s1053-2498(02)00493-x.Peer-Reviewed Original ResearchConceptsTotal lymphoid irradiationLymphoid irradiationAllograft rejectionPatients treated with total lymphoid irradiationIncreased incidence of coronary atherosclerosisMultiple episodes of rejectionCoronary atherosclerosisRecurrent allograft rejectionEpisodes of rejectionCoronary artery diseaseIncidence of coronary atherosclerosisCardiac transplantationHeart transplantationCoronary angiogramArtery diseaseIncreased incidenceControl groupMultiple episodesTransplantationPatientsAtherosclerosisRejectionAngiogram
2002
Alternative approach for use of a left ventricular assist device with a thrombosed prosthetic valve
Pelletier M, Chang C, Vagelos R, Robbins R. Alternative approach for use of a left ventricular assist device with a thrombosed prosthetic valve. The Journal Of Heart And Lung Transplantation 2002, 21: 402-404. PMID: 11897531, DOI: 10.1016/s1053-2498(01)00354-0.Peer-Reviewed Original ResearchConceptsLeft ventricular assist deviceVentricular assist deviceIncreased risk of thrombosisAortic outflow tractBovine pericardial patchTreating similar patientsRisk of thrombosisThrombosed prosthetic valveMechanical aortic valveProsthetic heart valvesOutflow tractPericardial patchAortic valveProsthetic valvesIncreased riskAssist devicePatientsHeart valves
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