2024
Randomized study of temporary diaphragm pacing for enhanced recovery after surgery in cardiac surgery patients at risk of prolonged mechanical ventilation
Hungate J, Onders R, Diasty M, Abu-Omar Y, Arora R, Baeza C, Elgudin Y, Gray K, Markowitz A, Pelletier M, Ribeiro I, Vega P, Rushing G, Sabik J. Randomized study of temporary diaphragm pacing for enhanced recovery after surgery in cardiac surgery patients at risk of prolonged mechanical ventilation. JTCVS Open 2024, 22: 76-84. PMID: 39780786, PMCID: PMC11704535, DOI: 10.1016/j.xjon.2024.09.031.Peer-Reviewed Original ResearchProlonged mechanical ventilationStandard of care groupRisk of prolonged mechanical ventilationMechanical ventilationCardiac surgeryDiaphragmatic pacingDiaphragm pacingTreatment groupsRandomized trialsHistory of chronic obstructive pulmonary diseaseLeft ventricular ejection fractionIntra-aortic balloon pumpDecrease mechanical ventilationCardiac surgery patientsVentricular ejection fractionHigh-risk patientsMulticenter randomized trialCare groupEnhanced recoveryChronic obstructive pulmonary diseaseRelative risk reductionIntensive care unitStandard of carePredictive enrichment strategiesObstructive pulmonary disease
2021
PILOT STUDY OF PERCUTANEOUS TEMPORARY DIAPHRAGM PACING WIRES IN CARDIAC SURGERY PATIENTS AT RISK OF PROLONGED MECHANICAL VENTILATION DURING THE COVID-19 PANDEMIC
Jarrett C, Onders R, Pelletier M, Abu-Omar Y, Baeza C, Elgudin Y, Markowitz A, Vega P, Sabik J. PILOT STUDY OF PERCUTANEOUS TEMPORARY DIAPHRAGM PACING WIRES IN CARDIAC SURGERY PATIENTS AT RISK OF PROLONGED MECHANICAL VENTILATION DURING THE COVID-19 PANDEMIC. Canadian Journal Of Cardiology 2021, 37: s112-s113. PMCID: PMC8523110, DOI: 10.1016/j.cjca.2021.07.213.Peer-Reviewed Original ResearchProlonged mechanical ventilationCardiac surgery patientsCardiac surgeryDiaphragm pacingMechanical ventilationDiaphragm functionSurgery patientsHigh-risk cardiac surgery patientsVentilator induced diaphragm dysfunctionRisk of prolonged mechanical ventilationDecreased ventilation timeLikelihood of extubationPrevent diaphragm atrophyHistory of TIAOpen heart surgeryProlonged mechanical ventilation patientsRelated adverse eventsOutcomes of DPDevice related adverse eventsRandomized controlled trialsDiaphragm atrophyDiaphragm dysfunctionProspective trialsMedian timeVentilation time
2020
Thirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery
Hirji SA, Percy ED, Zogg CK, Vaduganathan M, Kiehm S, Pelletier M, Kaneko T. Thirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery. The Annals Of Thoracic Surgery 2020, 110: 484-491. PMID: 31972128, PMCID: PMC7382395, DOI: 10.1016/j.athoracsur.2019.11.042.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementNonindex readmissionsCardiac surgeryNonindex hospitalNonindex hospital readmissionsCoronary artery bypassNational Readmission DatabaseAortic valve replacementCardiac surgery patientsMajor cardiac surgeryPatient risk profileHigh-volume centersUS adult patientsRegionalization of careFragmentation of careComorbidity burdenHospital mortalityIndex readmissionArtery bypassInitial hospitalizationAdult patientsSurgery patientsValve replacementHospital readmissionIndependent predictors
2019
Cardiac Surgery in Patients With Opioid Use Disorder: An Analysis of 1.7 Million Surgeries
Shah R, Hirji S, Percy E, Landino S, Yazdchi F, Bellavia A, Pelletier M, Shekar P, Kaneko T. Cardiac Surgery in Patients With Opioid Use Disorder: An Analysis of 1.7 Million Surgeries. The Annals Of Thoracic Surgery 2019, 109: 1194-1201. PMID: 31479643, DOI: 10.1016/j.athoracsur.2019.07.041.Peer-Reviewed Original ResearchConceptsOpioid use disorderCardiac surgeryIncreased risk of postoperative morbidityImpact of opioid use disorderRisk of postoperative morbidityOpioid epidemicAssociated with prolonged hospitalizationRisk factorsUse disorderOpioid use disorder statusCoronary artery bypass graftingNon-opioid usersPreoperative risk factorsCardiac surgery patientsPatient's preoperative risk factorsAcute kidney injuryArtery bypass graftingCardiac surgery outcomesIn-hospital mortalityCurrent opioid epidemicLonger hospital lengthImprove overall outcomesHigher hospital costsNational Inpatient SampleValve repairSignificance of Interstitial Lung Disease on Outcomes Following Cardiac Surgery
Hirji S, Ramirez-Del Val F, Ejiofor J, Lee J, Norman A, McGurk S, Pelletier M, Aranki S, Rawn J, Shekar P, Hunninghake G, Kaneko T. Significance of Interstitial Lung Disease on Outcomes Following Cardiac Surgery. The American Journal Of Cardiology 2019, 124: 1133-1139. PMID: 31405546, DOI: 10.1016/j.amjcard.2019.06.031.Peer-Reviewed Original ResearchConceptsInterstitial lung diseaseInterstitial lung disease patientsIdiopathic pulmonary fibrosisLong-term survivalLonger intensive care unitCardiac surgeryNon-ILD patientsIntensive care unitReintubation rateAssociated with shorter long-term survivalLung diseaseComparison cohortSeverity of interstitial lung diseaseShorter long-term survivalCare unitKaplan-Meier estimates of survivalIdiopathic pulmonary fibrosis cohortsRisk factorsInterstitial lung disease diagnosisSurvival analysisAcute pulmonary exacerbationsIncreased operative mortalityMedian follow-upCardiac surgery patientsRisk-adjusted survival analysis
2016
Efficacy of intraoperative cell salvage in decreasing perioperative blood transfusion rates in first-time cardiac surgery patients: a retrospective study
Côté C, Yip A, MacLeod J, O'Reilly B, Murray J, Ouzounian M, Brown C, Forgie R, Pelletier M, Hassan A. Efficacy of intraoperative cell salvage in decreasing perioperative blood transfusion rates in first-time cardiac surgery patients: a retrospective study. Canadian Journal Of Surgery 2016, 59: 330-336. PMID: 27668331, PMCID: PMC5042720, DOI: 10.1503/cjs.002216.Peer-Reviewed Original ResearchConceptsIntraoperative cell salvagePerioperative transfusion ratesCardiac surgeryTransfusion rateCell salvageTransfusion rates of packed red blood cellsRates of packed red blood cellsBlood productsFirst-time cardiac surgeryRetrospective analysis of patientsEffectiveness of intraoperative cell salvagePerioperative blood transfusion ratePacked red blood cellsBlood transfusion rateCardiac surgery patientsAnalysis of patientsReduce transfusion ratesRisk-adjusted effectCoagulation productsMultivariate logistic regressionPerioperative transfusionMediastinal drainagePostoperative bleedingPostoperative hemoglobinHematologic outcomes
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