2024
The prognostic utility of galectin-3 in patients undergoing cardiac surgery: a scoping review
Shah A, Ding Y, Walji D, Rabinovich G, Pelletier M, El-Diasty M. The prognostic utility of galectin-3 in patients undergoing cardiac surgery: a scoping review. Biomarkers 2024, 29: 485-493. PMID: 39422445, DOI: 10.1080/1354750x.2024.2415073.Peer-Reviewed Original ResearchConceptsAssociated with acute kidney injuryPostoperative atrial fibrillationGal-3 levelsLeft ventricular reverse remodelingCardiac surgeryAdverse outcomesGal-3Clinical risk prediction scorePreoperative plasma levelsVentricular reverse remodelingEuroSCORE II modelPlasma Gal-3 levelsPostoperative adverse outcomesAcute kidney injuryGalectin-3Group of patientsPredicting adverse outcomesRisk prediction scorePostoperative morbidityReverse remodelingPostoperative mortalityElectronic database searchPrognostic utilityAdult patientsKidney injury
2020
Acute kidney injury in renal transplant recipients undergoing cardiac surgery
Hundemer G, Srivastava A, Jacob K, Krishnasamudram N, Ahmed S, Boerger E, Sharma S, Pokharel K, Hirji S, Pelletier M, Safa K, Kulvichit W, Kellum J, Riella L, Leaf D. Acute kidney injury in renal transplant recipients undergoing cardiac surgery. Nephrology Dialysis Transplantation 2020, 36: 185-196. PMID: 32892219, PMCID: PMC7771983, DOI: 10.1093/ndt/gfaa063.Peer-Reviewed Original ResearchConceptsRenal transplant recipientsAcute kidney injuryNon-RTRsCardiac surgeryCalcineurin inhibitorsRisk factorsTransplant recipientsKidney injuryType of cardiac surgeryKidney diseaseRates of acute kidney injuryRisk of acute kidney injuryDeceased donorsGlobal Outcomes criteriaLiving donorsRetrospective cohort studyAssociated with higher ratesChronic kidney diseaseTrough levelsClinical characteristicsAcademic medical centerCohort studySurgeryHigh riskMedical CenterSafety‐net hospitals versus non‐safety centers and clinical outcomes after trans‐catheter aortic valve replacement
Sheikh M, Deo S, Riaz H, Raza S, Altarabsheh S, Wilson B, Elgudin Y, Cmolik B, Pelletier M, Markowitz A. Safety‐net hospitals versus non‐safety centers and clinical outcomes after trans‐catheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2020, 97: e425-e430. PMID: 32681697, DOI: 10.1002/ccd.29123.Peer-Reviewed Original ResearchConceptsValve replacementNational in-patient sampleLength of post-operative stayPropensity-matched cohort of patientsTrans-catheter aortic valve replacementPost-operative stayAortic valve replacementClinical co-variatesCohort of patientsAcute kidney injuryPropensity-matched cohortPost-procedural mortalityPost-procedural outcomesClinical outcomesKidney injurySecondary outcomesIn-patient samplePatientsLow-income patientsSafety-net hospitalHospitalOutcomesSafety-netIncome patientsNon-safety net hospitals
2019
Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Kolkailah A, Doukky R, Pelletier M, Volgman A, Kaneko T, Nabhan A. Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk. Cochrane Database Of Systematic Reviews 2019, 12: cd013319. PMID: 31860123, PMCID: PMC6984621, DOI: 10.1002/14651858.cd013319.pub2.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementLength of hospital stayLow surgical riskAortic valve replacementTranscatheter aortic valve implantationAcute kidney injuryRisk of PPM implantationRisk of atrial fibrillationSurgical riskAortic valve stenosisRandomised controlled trialsValve replacementAortic valve implantationAtrial fibrillationCardiac deathCertainty of evidenceMyocardial infarctionPPM implantationPermanent pacemakerValve implantationAssociated with shorter lengths of hospital stayNew-onset atrial fibrillationRisk ratioLong-term follow-up dataShorter length of hospital stayEnhanced recovery after cardiac surgery: fluid balance and incidence of acute kidney injury
Varelmann D, Shook D, Buric D, Yadzchi F, Madou I, Morth K, Bentain-Melanson M, Woo S, Manca C, Aranki S, Rawn J, Pelletier M, Shekar P, Kaneko T, Swanson J, Zammert M. Enhanced recovery after cardiac surgery: fluid balance and incidence of acute kidney injury. Journal Of Cardiothoracic And Vascular Anesthesia 2019, 33: s141-s142. DOI: 10.1053/j.jvca.2019.07.015.Peer-Reviewed Original ResearchIncidence of acute kidney injuryAcute kidney injuryStandard care groupCardiac surgeryAlbumin 5%Cardiopulmonary bypassKidney injuryHospital stayERAS pathwayFluid balanceOutcome data of patientsCare unitOccurrence of acute kidney injuryLength of hospital stayTotal fluid balanceChest tube removalKDIGO stage 1Care groupMultimodal pain managementWorsening metabolic acidosisSigns of hypovolemiaRestrictive fluid managementData of patientsEnhanced recoveryWilcoxon rank sum testCardiac Surgery in Patients With Opioid Use Disorder: An Analysis of 1.7 Million Surgeries
Shah R, Hirji S, Percy E, Landino S, Yazdchi F, Bellavia A, Pelletier M, Shekar P, Kaneko T. Cardiac Surgery in Patients With Opioid Use Disorder: An Analysis of 1.7 Million Surgeries. The Annals Of Thoracic Surgery 2019, 109: 1194-1201. PMID: 31479643, DOI: 10.1016/j.athoracsur.2019.07.041.Peer-Reviewed Original ResearchConceptsOpioid use disorderCardiac surgeryIncreased risk of postoperative morbidityImpact of opioid use disorderRisk of postoperative morbidityOpioid epidemicAssociated with prolonged hospitalizationRisk factorsUse disorderOpioid use disorder statusCoronary artery bypass graftingNon-opioid usersPreoperative risk factorsCardiac surgery patientsPatient's preoperative risk factorsAcute kidney injuryArtery bypass graftingCardiac surgery outcomesIn-hospital mortalityCurrent opioid epidemicLonger hospital lengthImprove overall outcomesHigher hospital costsNational Inpatient SampleValve repairCharacterizing Risks Associated With Mitral Annular Calcification in Mitral Valve Replacement
Kaneko T, Hirji S, Percy E, Aranki S, McGurk S, Body S, Heydarpour M, Mallidi H, Singh S, Pelletier M, Rawn J, Shekar P. Characterizing Risks Associated With Mitral Annular Calcification in Mitral Valve Replacement. The Annals Of Thoracic Surgery 2019, 108: 1761-1767. PMID: 31207248, DOI: 10.1016/j.athoracsur.2019.04.080.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCalcinosisEchocardiography, TransesophagealFemaleFollow-Up StudiesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHospital MortalityHumansIncidenceIntraoperative ComplicationsMaleMiddle AgedMitral ValvePostoperative ComplicationsRetrospective StudiesRisk AssessmentSeverity of Illness IndexSurvival RateUnited StatesConceptsMitral annular calcificationAssociated with increased operative mortalityPresence of mitral annular calcificationMV replacementOperative mortalityAnnular calcificationSociety of Thoracic Surgeons Adult Cardiac Surgery DatabaseMAC patientsAssociated with increased risk of acute kidney injuryAdult Cardiac Surgery DatabaseRisk of acute kidney injuryMitral valve (MVConcomitant tricuspid proceduresNon-MAC patientsObserved operative mortalityCardiac Surgery DatabaseMitral valve replacementAssociated with increased riskAdverse postoperative outcomesAcute kidney injuryIn-hospital complicationsTricuspid proceduresReoperation rateSurgery DatabaseValve replacement
2015
USING POST-OPERATIVE CREATININE TRAJECTORY TO DETERMINE CLINICAL IMPACT OF CARDIAC SURGERY-ASSOCIATED ACUTE KIDNEY INJURY
Percy E, Green A, MacLeod J, Yip A, Lutchmedial S, Brown C, Forgie R, Pelletier M, Murray J, Hassan A. USING POST-OPERATIVE CREATININE TRAJECTORY TO DETERMINE CLINICAL IMPACT OF CARDIAC SURGERY-ASSOCIATED ACUTE KIDNEY INJURY. Canadian Journal Of Cardiology 2015, 31: s184. DOI: 10.1016/j.cjca.2015.07.392.Peer-Reviewed Original Research
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