2022
Effect of Obesity on Risk of Hospitalization, Surgery, and Serious Infection in Biologic-Treated Patients With Inflammatory Bowel Diseases: A CA-IBD Cohort Study
Gu P, Luo J, Kim J, Paul P, Limketkai B, Sauk J, Park S, Parekh N, Zheng K, Rudrapatna V, Syal G, Ha C, McGovern D, Melmed G, Fleshner P, Eisenstein S, Ramamoorthy S, Dulai P, Boland B, Grunvald E, Mahadevan U, Ohno-Machado L, Sandborn W, Singh S. Effect of Obesity on Risk of Hospitalization, Surgery, and Serious Infection in Biologic-Treated Patients With Inflammatory Bowel Diseases: A CA-IBD Cohort Study. The American Journal Of Gastroenterology 2022, 117: 1639-1647. PMID: 35973139, DOI: 10.14309/ajg.0000000000001855.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseBiologic-treated patientsRisk of hospitalizationBody mass indexNormal body mass indexSerious infectionsBiologic agentsBowel diseaseCox proportional hazards analysisWorld Health Organization classificationEffect of obesityProportional hazards analysisElectronic health recordsCause hospitalizationVisceral obesityAdult patientsBaseline demographicsBiologic initiationBiologic therapyCohort studyEndoscopic outcomesMass indexOrganization classificationTreatment characteristicsStratified analysisEpidemiology of atrial fibrillation in the All of Us Research Program
Alonso A, Alam A, Kamel H, Subbian V, Qian J, Boerwinkle E, Cicek M, Clark C, Cohn E, Gebo K, Loperena-Cortes R, Mayo K, Mockrin S, Ohno-Machado L, Schully S, Ramirez A, Greenland P. Epidemiology of atrial fibrillation in the All of Us Research Program. PLOS ONE 2022, 17: e0265498. PMID: 35294480, PMCID: PMC8926244, DOI: 10.1371/journal.pone.0265498.Peer-Reviewed Original ResearchConceptsAtrial fibrillationNon-Hispanic whitesUs Research ProgramRisk factorsEpidemiology of AFIncidence of AFPresence of AFHigher body mass indexStudy of AFClinical risk factorsIncident atrial fibrillationCoronary heart diseaseBody mass indexElectronic health record dataMedical history dataMedical history surveyNon-Hispanic blacksHealth record dataAvailable EHR dataNon-Hispanic AsiansHeart failureStudy enrollmentMass indexEligible participantsMean age
2021
Geographic Variation in Obesity at the State Level in the All of Us Research Program
Clark C, Chandler P, Zhou G, Noel N, Achilike C, Mendez L, O’Connor G, Smoller J, Weiss S, Murphy S, Ommerborn M, Karnes J, Klimentidis Y, Jordan C, Hiatt R, Ramirez A, Loperena R, Mayo K, Cohn E, Ohno-Machado L, Boerwinkle E, Cicek M, Schully S, Mockrin S, Gebo K, Karlson E. Geographic Variation in Obesity at the State Level in the All of Us Research Program. Preventing Chronic Disease 2021, 18: e104. PMID: 34941480, PMCID: PMC8718125, DOI: 10.5888/pcd18.210094.Peer-Reviewed Original ResearchConceptsBody mass indexObesity prevalenceElectronic health recordsSevere obesityPrevalence estimatesParticipants' electronic health recordsObesity prevention strategiesNational population-based estimatesEHR dataPopulation-based estimatesOverall obesity prevalenceState-level geographic variationsPopulation health studiesUS participantsEnrollment visitMass indexObesity preventionHigh prevalenceHealth StudyPrecision health approachObesityPrevention strategiesUs Research ProgramLarge geographic variationsCohort dataPediatric data from the All of Us research program: demonstration of pediatric obesity over time
Giangreco N, Lina S, Qian J, Kuoame A, Subbian V, Boerwinkle E, Cicek M, Clark C, Cohen E, Gebo K, Loperena-Cortes R, Mayo K, Mockrin S, Ohno-Machado L, Schully S, Tatonetti N, Ramirez A. Pediatric data from the All of Us research program: demonstration of pediatric obesity over time. JAMIA Open 2021, 4: ooab112. PMID: 35155998, PMCID: PMC8827025, DOI: 10.1093/jamiaopen/ooab112.Peer-Reviewed Original ResearchRacial, ethnic, and gender differences in obesity and body fat distribution: An All of Us Research Program demonstration project
Karnes J, Arora A, Feng J, Steiner H, Sulieman L, Boerwinkle E, Clark C, Cicek M, Cohn E, Gebo K, Loperena-Cortes R, Ohno-Machado L, Mayo K, Mockrin S, Ramirez A, Schully S, Klimentidis Y. Racial, ethnic, and gender differences in obesity and body fat distribution: An All of Us Research Program demonstration project. PLOS ONE 2021, 16: e0255583. PMID: 34358277, PMCID: PMC8345840, DOI: 10.1371/journal.pone.0255583.Peer-Reviewed Original ResearchConceptsBody mass indexBody fat distributionNon-Hispanic blacksNon-Hispanic whitesAlanine aminotransferaseNHB participantsFat distributionAge-adjusted obesity prevalenceNutrition Examination Survey dataBaseline physical examinationRace/ethnicityElectronic health recordsNHB womenWaist circumferenceMass indexHip ratioNHB menPhysical examinationNational HealthObesity prevalenceObesity ratesGender differencesObesityUs Research ProgramNHW participants