2014
Low Adherence to Helicobacter pylori Testing in Hospitalized Patients with Bleeding Peptic Ulcer Disease
Kim JJ, Lee JS, Olafsson S, Laine L. Low Adherence to Helicobacter pylori Testing in Hospitalized Patients with Bleeding Peptic Ulcer Disease. Helicobacter 2014, 19: 98-104. PMID: 24617668, DOI: 10.1111/hel.12114.Peer-Reviewed Original ResearchConceptsH. pylori testingProportion of patientsIndex hospitalizationHospitalized patientsConsecutive hospitalized patientsPeptic ulcer diseaseHelicobacter pylori testingInitial endoscopyUlcer diseaseSerologic testingSingle centerEndoscopy databaseSociety guidelinesGastric ulcerLow adherencePatientsUlcersMultivariate analysisHelicobacter pyloriHospitalizationDirect testingBiopsyTestingEndoscopyPylori
2005
The effect of GI bleeding on Helicobacter pylori diagnostic testing: a prospective study at the time of bleeding and 1 month later
Laine LA, Nathwani RA, Naritoku W. The effect of GI bleeding on Helicobacter pylori diagnostic testing: a prospective study at the time of bleeding and 1 month later. Gastrointestinal Endoscopy 2005, 62: 853-859. PMID: 16301025, DOI: 10.1016/j.gie.2005.09.019.Peer-Reviewed Original ResearchConceptsH pylori densityAcute GI bleedingInflammatory cell infiltrationH pyloriGI bleedingHistologic examinationCohort studyCell infiltrationDiagnostic testingBlinded histologic examinationH pylori testingAcute variceal bleedingProspective cohort studyUrban county hospitalProton pump inhibitorsTime of bleedingRapid urease testingVariceal bleedingCase seriesEndoscopic biopsyProspective studyPump inhibitorsBiopsy specimensUrease testingCounty Hospital
1999
Helicobacter pylori: drowning in a pool of blood?
Laine L, Cohen H. Helicobacter pylori: drowning in a pool of blood? Gastrointestinal Endoscopy 1999, 49: 398-402. PMID: 10049431, DOI: 10.1016/s0016-5107(99)70024-6.Commentaries, Editorials and Letters
1998
Accuracy of CLOtest after Helicobacter pylori therapy
Laine L, Suchower L, Johnson E, Ronca P, Neil G. Accuracy of CLOtest after Helicobacter pylori therapy. Gastrointestinal Endoscopy 1998, 47: 250-253. PMID: 9540877, DOI: 10.1016/s0016-5107(98)70321-9.Peer-Reviewed Original ResearchConceptsHelicobacter pylori therapyPylori therapyOmeprazole/amoxicillinCompletion of therapyDouble-blind trialRapid urease testingMore effective therapiesEndoscopic biopsy testsOmeprazole therapyAdditional therapyMost patientsDual therapyUnsuccessful treatmentUrease testingEffective therapyPositive testPatientsH. pyloriTherapyCLOtestBiopsy testsDecreased numberWeeksNegative resultsAmoxicillinEffect of blood on rapid urease testing of gastric mucosal biopsy specimens
Laine L, Sidhom O, Emami S, Estrada R, Cohen H. Effect of blood on rapid urease testing of gastric mucosal biopsy specimens. Gastrointestinal Endoscopy 1998, 47: 141-143. PMID: 9512278, DOI: 10.1016/s0016-5107(98)70346-3.Peer-Reviewed Original ResearchConceptsRapid urease testBiopsy specimensUrease testEffect of bloodRapid urease test resultsGastric mucosal biopsy specimensMucosal biopsy specimensRapid urease testingGastric biopsy specimensUrease test resultsGastric bodyUrease testingPositive testDiscordant resultsBloodCLOtestPyloriTekHoursPatientsAntrumBiopsyMucosaEndoscopy
1996
Prospective comparison of commercially available rapid urease tests for the diagnosis of Helicobacter pylori
Laine L, Lewin D, Naritoku W, Estrada R, Cohen H. Prospective comparison of commercially available rapid urease tests for the diagnosis of Helicobacter pylori. Gastrointestinal Endoscopy 1996, 44: 523-526. PMID: 8934155, DOI: 10.1016/s0016-5107(96)70002-0.Peer-Reviewed Original ResearchThe influence of warming on rapid urease test results: a prospective evaluation
Laine L, Estrada R, Lewin D, Cohen H. The influence of warming on rapid urease test results: a prospective evaluation. Gastrointestinal Endoscopy 1996, 44: 429-432. PMID: 8905363, DOI: 10.1016/s0016-5107(96)70094-9.Peer-Reviewed Original ResearchThe influence of size or number of biopsies on rapid urease test results: a prospective evaluation
Laine L, Chun D, Stein C, El-Beblawi I, Sharma V, Chandrasoma P. The influence of size or number of biopsies on rapid urease test results: a prospective evaluation. Gastrointestinal Endoscopy 1996, 43: 49-53. PMID: 8903818, DOI: 10.1016/s0016-5107(96)70260-2.Peer-Reviewed Original ResearchConceptsRegular biopsiesPositive testJumbo biopsyForceps biopsyAmount of tissueRapid urease test resultsHelicobacter pylori infectionNumber of biopsiesRapid urease testingUrease test resultsValuable diagnostic toolEndoscopic biopsyProspective evaluationPylori infectionUrease testingDiagnostic yieldHistologic examinationUrease testBiopsyRapid ureasePatientsFalse negative rateDiagnostic testsInterobserver agreementMean time