2024
Ocular Gene Therapy: An Overview of Viral Vectors, Immune Responses, and Future Directions
Banou L, Sarrafpour S, Teng C, Liu J. Ocular Gene Therapy: An Overview of Viral Vectors, Immune Responses, and Future Directions. The Yale Journal Of Biology And Medicine 2024, 97: 491-503. PMID: 39703610, PMCID: PMC11650918, DOI: 10.59249/hwid7537.Peer-Reviewed Original ResearchConceptsAdeno-associated virusOcular gene therapyGene therapyFood and Drug AdministrationViral vectorsImmune responsePotential application of gene therapyClinical trialsApproval of voretigene neparvovecViral vector-based therapyApplication of gene therapyImproved delivery techniquesVector-based therapyImmune-privileged statusInduce immune responsesReduced immune responseVoretigene neparvovecContralateral eyeRetinal dystrophyImmune privilegeOcular diseasesDeliver genesEye diseaseTherapeutic efficacyTherapy
2016
The Application of a Contact Lens Sensor in Detecting 24‐Hour Intraocular Pressure‐Related Patterns
Xu SC, Gauthier AC, Liu J. The Application of a Contact Lens Sensor in Detecting 24‐Hour Intraocular Pressure‐Related Patterns. Journal Of Ophthalmology 2016, 2016: 4727423. PMID: 27525110, PMCID: PMC4976175, DOI: 10.1155/2016/4727423.Peer-Reviewed Original ResearchContact lens sensorDisease progressionPrimary angle-closure glaucomaPrimary open-angle glaucomaCurrent glaucoma managementIOP-lowering interventionsSingle IOP measurementDisease statesThyroid eye diseaseAngle-closure glaucomaNormal-tension glaucomaOpen-angle glaucomaVisual field progressionIntraocular pressure fluctuationCause of blindnessOcular hypertensionClinic hoursClinical variablesGlaucoma managementField progressionDisease advancementEye diseaseIOP measurementsGlaucomaIOP
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