2025
Palliative care in acute care surgery: research challenges and opportunities
Maiga A, Ho V, Morris R, Kodadek L, Puzio T, Tominaga G, Tabata-Kelly M, Cooper Z. Palliative care in acute care surgery: research challenges and opportunities. Trauma Surgery & Acute Care Open 2025, 10: e001615. PMID: 40124208, PMCID: PMC11927415, DOI: 10.1136/tsaco-2024-001615.Peer-Reviewed Original ResearchAcute care surgeryPalliative care researchPalliative careCare researchEnd-of-life carePractice palliative carePalliative care interventionsPrimary palliative careSpecialty palliative careLife-prolonging careEnd-of-lifeRelief of sufferingQuality of lifeHigh-quality researchCare interventionsSymptom managementAdministrative dataAcute care surgeonsCareEmergency surgical conditionsSurgical illnessPrimary data collectionEffective communicationNarrative reviewCritical surgical illnessPrimary palliative care in acute care surgery: an American Association for the Surgery of Trauma Critical Care Committee and Palliative Care Committee clinical consensus document
Kodadek L, Cook M, Young J, Cottrell-Cumber S, Farrell M, Jawa R, Kirsch J, Nohra E, Haruta A, Lueckel S, Maerz L, Toevs C, Sanchez S, Kaups K, Pathak A, Zonies D, Cuschieri J, Stein D, Cooper Z, Committee A. Primary palliative care in acute care surgery: an American Association for the Surgery of Trauma Critical Care Committee and Palliative Care Committee clinical consensus document. Trauma Surgery & Acute Care Open 2025, 10: e001616. DOI: 10.1136/tsaco-2024-001616.Peer-Reviewed Original Research
2024
Pancreaticoduodenectomy in trauma patients with grade IV–V duodenal or pancreatic injuries: a post hoc analysis of an EAST multicenter trial
Choron R, Piplani C, Kuzinar J, Teichman A, Bargoud C, Sciarretta J, Smith R, Hanos D, Afif I, Beard J, Dhillon N, Zhang A, Ghneim M, Devasahayam R, Gunter O, Smith A, Sun B, Cao C, Reynolds J, Hilt L, Holena D, Chang G, Jonikas M, Echeverria-Rosario K, Fung N, Anderson A, Fitzgerald C, Dumas R, Levin J, Trankiem C, Yoon J, Blank J, Hazelton J, McLaughlin C, Al-Aref R, Kirsch J, Howard D, Scantling D, Dellonte K, Vella M, Hopkins B, Shell C, Udekwu P, Wong E, Joseph B, Lieberman H, Ramsey W, Stewart C, Alvarez C, Berne J, Nahmias J, Puente I, Patton J, Rakitin I, Perea L, Pulido O, Ahmed H, Keating J, Kodadek L, Wade J, Henry R, Schreiber M, Benjamin A, Khan A, Mann L, Mentzer C, Mousafeiris V, Mulita F, Reid-Gruner S, Sais E, Foote C, Palacio C, Argandykov D, Kaafarani H, Manderski M, Moko L, Narayan M, Seamon M. Pancreaticoduodenectomy in trauma patients with grade IV–V duodenal or pancreatic injuries: a post hoc analysis of an EAST multicenter trial. Trauma Surgery & Acute Care Open 2024, 9: e001438. PMID: 39717488, PMCID: PMC11664373, DOI: 10.1136/tsaco-2024-001438.Peer-Reviewed Original ResearchLonger intensive care unit length of stayGrade IV-VBlood product requirementsNon-PD patientsGI complicationsPancreatic injuryPD patientsMulticenter retrospective comparative studyLonger intensive care unit lengthAmerican Association for the SurgeryNon-PDIntensive care unit length of stayGrade VUnit length of stayMultivariate logistic regression analysisIV-VPancreatic ductal injuryProcedure-related morbiditySubanalysis of patientsRetrospective comparative studyLevel 1 trauma centerNon-PD groupLogistic regression analysisYears of agePost hoc analysisOpportunities for Incorporation of Primary Palliative Care in Acute Care Surgery: A Narrative Review.
Lynn A, Miller S, Brackett A, Kodadek L. Opportunities for Incorporation of Primary Palliative Care in Acute Care Surgery: A Narrative Review. American Journal Of Hospice And Palliative Medicine® 2024, 10499091241309087. PMID: 39680802, DOI: 10.1177/10499091241309087.Peer-Reviewed Original ResearchPrimary palliative careAcute care surgeryPalliative carePalliative care principlesPractice of acute care surgeryAcute care surgical patientsNarrative reviewPrimary surgical teamCaregiver supportSymptom managementCare principlesClinician perspectivesSeverity of illnessPalliative interventionsCareSignificant barriersPractice existPromote educationIdentification of patientsIncreased awarenessBenefit patientsSurgical traineesSurgical settingPatient populationCultural factorsScanning the aged to minimize missed injury: An Eastern Association for the Surgery of Trauma multicenter study
Ho V, Kishawi S, Hill H, O'Brien J, Ratnasekera A, Seng S, Ton T, Butts C, Muller A, Diaz B, Baltazar G, Petrone P, Pacheco T, Morrissey S, Chung T, Biller J, Jacobson L, Williams J, Nebughr C, Udekwu P, Tann K, Piehl C, Veatch J, Capasso T, Kuncir E, Kodadek L, Miller S, Altan D, Mentzer C, Damiano N, Burke R, Earley A, Doris S, Villa E, Wilkinson M, Dixon J, Wu E, Moncrief M, Palmer B, Herzing K, Egodage T, Williams J, Haan J, Lightwine K, Colling K, Harry M, Nahmias J, Tay-Lasso E, Cuschieri J, Hinojosa C, Claridge J. Scanning the aged to minimize missed injury: An Eastern Association for the Surgery of Trauma multicenter study. Journal Of Trauma And Acute Care Surgery 2024, 98: 101-110. PMID: 38797882, PMCID: PMC11599468, DOI: 10.1097/ta.0000000000004390.Peer-Reviewed Original ResearchNegative predictive valueHigh-risk criteriaBlunt trauma patientsPan-scanTorso CTMissed injuriesComputed tomographyTrauma patientsClinical algorithmInjury diagnosisIncidence of blunt traumaPositive clinical findingsPhysical exam findingsLack of evidence-based guidanceMulticenter studyClinical findingsProspective validationExam findingsEvidence-based guidanceBlunt traumaClinical useGeriatric patientsPatientsPredictive valueTrauma populationTools for Surgical Decision-Making #486
Miller S, Kodadek L, Morrison L. Tools for Surgical Decision-Making #486. Journal Of Palliative Medicine 2024, 27: 1267-1269. PMID: 39008409, DOI: 10.1089/jpm.2024.0243.Peer-Reviewed Original ResearchFever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
Nohra E, Appelbaum R, Farrell M, Carver T, Jung H, Kirsch J, Kodadek L, Mandell S, Nassar A, Pathak A, Paul J, Robinson B, Cuschieri J, Stein D. Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document. Trauma Surgery & Acute Care Open 2024, 9: e001303. PMID: 38835635, PMCID: PMC11149120, DOI: 10.1136/tsaco-2023-001303.Peer-Reviewed Original ResearchAmerican Association for the SurgeryIntensive care unitClinical consensus documentCatheter-associated urinary infectionDuration of antibiotic treatmentCatheter-related bloodstream infectionNecrotizing soft tissue infectionConsensus documentWorkup of feverIntra-abdominal infectionsSurgical intensive care unitSoft tissue infectionsEvaluation of feverSurgical site infectionVentilator-associated pneumoniaDiagnosis of infectionSurgical intensive careEmpirical antibioticsBloodstream infectionsRespiratory specimensUrinary infectionTissue infectionsSite infectionAntibiotic treatmentTreat infectionsThe impact of postoperative enteral nutrition on duodenal injury outcomes: A post hoc analysis of an Eastern Association for the Surgery of Trauma multicenter trial
Choron R, Rallo M, Piplani C, Youssef S, Teichman A, Bargoud C, Sciarretta J, Smith R, Hanos D, Afif I, Beard J, Dhillon N, Zhang A, Ghneim M, Devasahayam R, Gunter O, Smith A, Sun B, Cao C, Reynolds J, Hilt L, Holena D, Chang G, Jonikas M, Echeverria-Rosario K, Fung N, Anderson A, Dumas R, Fitzgerald C, Levin J, Trankiem C, Yoon J, Blank J, Hazelton J, McLaughlin C, Al-Aref R, Kirsch J, Howard D, Scantling D, Dellonte K, Vella M, Hopkins B, Shell C, Udekwu P, Wong E, Joseph B, Lieberman H, Ramsey W, Stewart C, Alvarez C, Berne J, Nahmias J, Puente I, Patton J, Rakitin I, Perea L, Pulido O, Ahmed H, Keating J, Kodadek L, Wade J, Henry R, Schreiber M, Benjamin A, Khan A, Mann L, Mentzer C, Mousafeiris V, Mulita F, Reid-Gruner S, Sais E, Foote C, Palacio C, Argandykov D, Kaafarani H, Manderski M, Narayan M, Seamon M. The impact of postoperative enteral nutrition on duodenal injury outcomes: A post hoc analysis of an Eastern Association for the Surgery of Trauma multicenter trial. Journal Of Trauma And Acute Care Surgery 2024, 97: 928-936. PMID: 38745354, DOI: 10.1097/ta.0000000000004303.Peer-Reviewed Original ResearchENS patientsLeak closurePost hoc analysisInfectious complicationsPredictors of leakPostoperative enteral nutritionIntra-abdominal abscessLevel 1 trauma centerGroups(all P <Associated with decreased timeShorter hospital lengthTraumatic duodenal injuryCompared to PNDays NPOKruskal-Wallis testEnteral nutritionSurgical repairMulticenter trialPancreatic injuryDuodenal leakMulticenter studyHospital courseProlonged hospitalizationPN groupHospital lengthRole of Vena Cava Filter in the Prophylaxis and Treatment of Venous Thromboembolism in Injured Adult Patients: A Systematic Review, Meta-Analysis, and Practice Management Guideline from the Eastern Association for the Surgery of Trauma [RETRACTED].
Bhattacharya B, Kodadek L, Nichiporenko I, Morrissey S, Kirsch J, Choi J, Ladhani H, Kasotakis G, Mukherjee K, Narsule C, Sharma R, Ruangvoravat L, Grushka J, Rattan R, Bugaev N. Role of Vena Cava Filter in the Prophylaxis and Treatment of Venous Thromboembolism in Injured Adult Patients: A Systematic Review, Meta-Analysis, and Practice Management Guideline from the Eastern Association for the Surgery of Trauma [RETRACTED]. Journal Of Trauma And Acute Care Surgery 2024 PMID: 38454308, DOI: 10.1097/ta.0000000000004289.Peer-Reviewed Original ResearchInferior vena cava filterInferior vena cavaQuality of evidenceDeep vein thrombosisInjured adult patientsRandomized controlled trialsVenous thromboembolismInjured patientsIVC filtersPulmonary embolismAdult patientsInferior vena cava filter useMeta-analysisEastern Association for the Surgery of TraumaTreatment of venous thromboembolismEvidence-based guidelinesPlacement of IVC filtersSystematic review/meta-analysisAcute venous thromboembolismVena cava filterPrevent venous thromboembolismPractice management guidelinesSurgery of TraumaLength of stayRecommendations AssessmentGuideline Implementation Is Improving Trauma Care in the Wild, Wild West
Jopling J, Kodadek L, Haut E. Guideline Implementation Is Improving Trauma Care in the Wild, Wild West. JAMA Surgery 2024, 159: 372-373. PMID: 38265808, DOI: 10.1001/jamasurg.2023.7154.Peer-Reviewed Original ResearchWhole blood resuscitation for injured patients requiring transfusion: A systematic review, meta-analysis, and practice management guideline from the Eastern Association for the Surgery of Trauma
Meizoso J, Cotton B, Lawless R, Kodadek L, Lynde J, Russell N, Gaspich J, Maung A, Anderson C, Reynolds J, Haines K, Kasotakis G, Freeman J. Whole blood resuscitation for injured patients requiring transfusion: A systematic review, meta-analysis, and practice management guideline from the Eastern Association for the Surgery of Trauma. Journal Of Trauma And Acute Care Surgery 2024, 97: 460-470. PMID: 38531812, DOI: 10.1097/ta.0000000000004327.Peer-Reviewed Original ResearchAdult civilian trauma patientsCivilian trauma patientsWhole blood resuscitationLength of stayICU length of stayMeta-analysisTrauma patientsSystematic reviewAssess quality of evidenceBlood transfusionInjured patientsBlood-based resuscitationBlood resuscitationEastern Association for the Surgery of TraumaInfectious complicationsQuality of evidenceRisk of biasEvidence-based recommendationsComponent therapyEnglish-language studiesAssociated with decreased mortalityHemorrhage control proceduresICU lengthWeb of ScienceCINAHL PlusCurrent diagnosis and management of acute colonic diverticulitis: What you need to know
Kodadek L, Davis K. Current diagnosis and management of acute colonic diverticulitis: What you need to know. Journal Of Trauma And Acute Care Surgery 2024, 97: 1-10. PMID: 38509056, DOI: 10.1097/ta.0000000000004304.Peer-Reviewed Original ResearchStepped collaborative care for trauma: giant leaps for health equity
Rivero R, Kodadek L. Stepped collaborative care for trauma: giant leaps for health equity. Trauma Surgery & Acute Care Open 2024, 9: e001359. PMID: 38312238, PMCID: PMC10836370, DOI: 10.1136/tsaco-2024-001359.Peer-Reviewed Original Research
2023
Changes in Older Adult Trauma Quality When Evaluated Using Longer-Term Outcomes vs In-Hospital Mortality
Zogg C, Cooper Z, Peduzzi P, Falvey J, Castillo-Angeles M, Kodadek L, Staudenmayer K, Davis K, Tinetti M, Lichtman J. Changes in Older Adult Trauma Quality When Evaluated Using Longer-Term Outcomes vs In-Hospital Mortality. JAMA Surgery 2023, 158: e234856. PMID: 37792354, PMCID: PMC10551815, DOI: 10.1001/jamasurg.2023.4856.Peer-Reviewed Original ResearchConceptsHospital-level factorsTraumatic brain injurySevere traumatic brain injuryHospital mortalityTrauma QualityOlder adultsHip fractureComposite scoreHigher risk-adjusted oddsLevel 1 trauma centerIn-Hospital MortalityRisk-adjusted oddsLong-term outcomesMultivariable logistic regressionNontrauma centersTrauma patientsTerm outcomesTrauma centerPrimary diagnosisBrain injuryTrauma systemMAIN OUTCOMEMedicare feeService claimsForms of traumaGoals of Care for the Critically Injured Trauma Patient
Kodadek L. Goals of Care for the Critically Injured Trauma Patient. Current Trauma Reports 2023, 10: 1-8. DOI: 10.1007/s40719-023-00265-5.Peer-Reviewed Original ResearchGoals of carePrimary palliative carePurpose of ReviewToHigh-quality careOperative interventionTrauma patientsPalliative careCare discussionsCare conversationsPatientsQuality careOptimal timingNonbeneficial careCareImproved qualityRecent studiesSpecial considerationAppropriate goalsAdmissionReviewToPhysiciansThe interaction between geriatric and neighborhood vulnerability: Delineating prehospital risk among older adult emergency general surgery patients
Zogg C, Falvey J, Kodadek L, Staudenmayer K, Davis K. The interaction between geriatric and neighborhood vulnerability: Delineating prehospital risk among older adult emergency general surgery patients. Journal Of Trauma And Acute Care Surgery 2023, 96: 400-408. PMID: 37962136, PMCID: PMC10922165, DOI: 10.1097/ta.0000000000004191.Peer-Reviewed Original ResearchGeriatric vulnerabilitiesOlder adultsEGS careAdverse outcomesHospital Frailty Risk ScoreEmergency general surgery patientsGreater riskFlorida State Inpatient DatabaseFrailty Risk ScoreGeneral surgery patientsState Inpatient DatabasesArea Deprivation IndexEthnic minority patientsNeighborhood vulnerabilityEGS outcomesHazard ratioOlder patientsSurgery patientsPatient ageEGS conditionsInpatient DatabaseVulnerable patientsPatient residesMinority patientsRisk scoreManagement of Blunt Chest Trauma
Griffard J, Kodadek L. Management of Blunt Chest Trauma. Surgical Clinics Of North America 2023, 104: 343-354. PMID: 38453306, DOI: 10.1016/j.suc.2023.09.007.Peer-Reviewed Original ResearchA Rationale and Systems Impact for Geriatric Trauma and Acute Care Surgery
Briggs A, Kodadek L. A Rationale and Systems Impact for Geriatric Trauma and Acute Care Surgery. 2023, 17-28. DOI: 10.1007/978-3-031-30651-8_3.ChaptersAcute care surgeryCare surgeryOlder adultsLonger hospital staySevere postoperative complicationsBaseline functional statusGoals of careHospital stayPostoperative complicationsGeriatric traumaGeriatric patientsFunctional statusSurgical conditionsHigh-risk operationsCare planningCare plansCare programInpatient operationsUS populationNumber of AmericansOptimal outcomesComplicationsPatientsSurgeryAdultsDiverticulitis in Older Adults: Is Cognitive Impairment Associated With Outcomes?
Kodadek L, Moore M, Canner J, Schneider E. Diverticulitis in Older Adults: Is Cognitive Impairment Associated With Outcomes? Journal Of Surgical Research 2023, 291: 359-366. PMID: 37506436, DOI: 10.1016/j.jss.2023.06.015.Peer-Reviewed Original ResearchConceptsColonic diverticulitisCognitive impairmentEmergency departmentOlder adultsHospital mortalityOperative interventionInpatient admissionsPrimary diagnosisMultivariable Poisson regression modelsNationwide Emergency Department SamplePrimary payer statusRetrospective cohort studyElixhauser Comorbidity IndexEmergency Department SampleComorbid cognitive impairmentPoisson regression modelsComorbidity indexComplicated diverticulitisCognitive impairment statusCohort studyED encountersPatient ageED carePayer statusRelative riskCurrent use of the National Surgical Quality Improvement Program surgical risk calculator in academic surgery: a mixed-methods study
Miller S, Azar S, Farrelly J, Salzman G, Broderick M, Sanders K, Anto V, Patel N, Cordova A, Schuster K, Jones T, Kodadek L, Gross C, Morton J, Rosenthal R, Becher R. Current use of the National Surgical Quality Improvement Program surgical risk calculator in academic surgery: a mixed-methods study. Surgery In Practice And Science 2023, 13: 100173. PMID: 37502700, PMCID: PMC10373440, DOI: 10.1016/j.sipas.2023.100173.Peer-Reviewed Original ResearchNSQIP Surgical Risk CalculatorSurgical Risk CalculatorNonelective casesRisk calculatorNational Surgical Quality Improvement Program Surgical Risk CalculatorHigh-risk patientsGeneral clinical practiceSpecific clinical scenariosCross-sectional studyElectronic health recordsFrail patientsPrimary outcomeHalf of respondentsPreoperative assessmentContemporary surgical practiceClinical practiceClinical scenariosSurgical practicePast monthPatientsSurgeonsTraining statusSurrogate consentPotential interventionsHealth records
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