2024
Mobile Stroke Unit Management in Patients With Acute Ischemic Stroke Eligible for Intravenous Thrombolysis
Mac Grory B, Sun J, Alhanti B, Lusk J, Li F, Adeoye O, Furie K, Hasan D, Messe S, Sheth K, Schwamm L, Smith E, Bhatt D, Fonarow G, Saver J, Xian Y, Grotta J. Mobile Stroke Unit Management in Patients With Acute Ischemic Stroke Eligible for Intravenous Thrombolysis. JAMA Neurology 2024, 81 PMID: 39466286, DOI: 10.1001/jamaneurol.2024.3659.Peer-Reviewed Original ResearchEmergency medical servicesEmergency medical service managementMobile stroke unitPrehospital managementSymptomatic intracranial hemorrhageHospital dischargeGlobal disabilityIn-hospital mortalityEfficacy end pointUtility-weighted modified Rankin scaleStroke unit managementAcute ischemic strokeIschemic strokePrimary analytic cohortDiagnosis of ischemic strokeIntravenous thrombolysisAmerican Heart AssociationEnd pointsGuidelines-StrokeUW-mRSSecondary efficacy end pointsMain OutcomesMedical servicesStroke unitAmbulation status
2019
Recommendations for the Establishment of Stroke Systems of Care: A 2019 Update: A Policy Statement From the American Stroke Association
Adeoye O, Nyström K, Yavagal D, Luciano J, Nogueira R, Zorowitz R, Khalessi A, Bushnell C, Barsan W, Panagos P, Alberts M, Tiner A, Schwamm L, Jauch E. Recommendations for the Establishment of Stroke Systems of Care: A 2019 Update: A Policy Statement From the American Stroke Association. Stroke 2019, 50: e187-e210. PMID: 31104615, DOI: 10.1161/str.0000000000000173.Peer-Reviewed Original ResearchConceptsAmerican Stroke AssociationStroke systemsStroke AssociationStroke center certificationMobile stroke unitEmergency medical servicesHospital dischargeSecondary preventionStroke centersEndovascular therapyStroke unitPrimary preventionCenter certificationNeurocritical careAssociation recommendationsCareBasis of improvementStroke recognitionMedical servicesHealthcare agenciesScientific evidenceHealthcare policyAppropriate facilitiesPreventionSignificant changes
2018
Evaluation of a score for the prehospital distinction between cerebrovascular disease and stroke mimic patients
Geisler F, Ali S, Ebinger M, Kunz A, Rozanski M, Waldschmidt C, Weber J, Wendt M, Winter B, Schwamm L, Audebert H. Evaluation of a score for the prehospital distinction between cerebrovascular disease and stroke mimic patients. International Journal Of Stroke 2018, 14: 400-408. PMID: 30303808, DOI: 10.1177/1747493018806194.Peer-Reviewed Original ResearchConceptsStroke mimic patientsIndividual patient characteristicsMimic patientsCerebrovascular diseaseStroke mimicsPatient characteristicsFocal neurological deficitsCerebrovascular disease patientsCertain patient characteristicsMobile stroke unitPre-hospital settingSevere strokeArterial hypertensionNeurological deficitsStroke unitAtrial fibrillationDisease patientsSudden onsetEmergency physiciansHospital destinationPatientsDiscriminative valueFinal analysisDiseaseStroke
2013
Impact on Clinical and Cost Outcomes of a Centralized Approach to Acute Stroke Care in London: A Comparative Effectiveness Before and After Model
Hunter R, Davie C, Rudd A, Thompson A, Walker H, Thomson N, Mountford J, Schwamm L, Deanfield J, Thompson K, Dewan B, Mistry M, Quoraishi S, Morris S. Impact on Clinical and Cost Outcomes of a Centralized Approach to Acute Stroke Care in London: A Comparative Effectiveness Before and After Model. PLOS ONE 2013, 8: e70420. PMID: 23936427, PMCID: PMC3731285, DOI: 10.1371/journal.pone.0070420.Peer-Reviewed Original ResearchConceptsAcute stroke careHyper-acute stroke unitLength of stayStroke careStroke patientsReduced hospital lengthAcute stroke patientsNational time trendsDecision analytic modelHospital lengthPatient characteristicsStroke RegisterStroke unitClinical outcomesSpecialist careLocal hospitalPatientsSurvival rateComparative effectivenessCost outcomesSurvival analysisStayTotal cost savingsMortalityCare
2012
Assessing Stroke Patients for Rehabilitation During the Acute Hospitalization: Findings From the Get With The Guidelines–Stroke Program
Bettger J, Kaltenbach L, Reeves M, Smith E, Fonarow G, Schwamm L, Peterson E. Assessing Stroke Patients for Rehabilitation During the Acute Hospitalization: Findings From the Get With The Guidelines–Stroke Program. Archives Of Physical Medicine And Rehabilitation 2012, 94: 38-45. PMID: 22858797, DOI: 10.1016/j.apmr.2012.06.029.Peer-Reviewed Original ResearchConceptsGuidelines-Stroke programStroke patientsAcute hospitalizationAcute strokeAcute hospitalsGWTG-Stroke programAcute stroke patientsProspective cohortStroke unitMultivariable analysisNonwhite raceRehabilitation careAcute assessmentMAIN OUTCOMEStroke diagnosisPatientsRehabilitation servicesHospitalizationRehabilitationHospitalStrokeUnited StatesAssessmentAdmissionCohortTelestroke increases use of acute stroke therapy
Müller-Barna P, Schwamm L, Haberl R. Telestroke increases use of acute stroke therapy. Current Opinion In Neurology 2012, 25: 5-10. PMID: 22157105, DOI: 10.1097/wco.0b013e32834d5fe4.Peer-Reviewed Original ResearchConceptsTelestroke networkStroke careUsage of guidelinesAcute stroke careAcute stroke therapyIschemic stroke patientsRate of thrombolysisNew therapeutic modalitiesStroke teamAcute strokeNeurological examinationStroke unitStroke patientsStroke therapyStroke managementImproved outcomesTherapeutic modalitiesTelestroke servicesRemote reviewUnderserved areasHigh-quality videoconferencingCareIncrease useRegular basisThrombolysis
2011
Stroke Quality Metrics
Parker C, Schwamm L, Fonarow G, Smith E, Reeves M. Stroke Quality Metrics. Stroke 2011, 43: 155-162. PMID: 21980213, DOI: 10.1161/strokeaha.111.635011.Peer-Reviewed Original ResearchConceptsPatient-centered outcomesQuality of carePublic reportingStroke metricsAcute hospital settingHigh-quality studiesPositive associationQuality improvement activitiesStroke outcomeStroke unitEmbase databasesEligible studiesPatient outcomesHospital settingEligibility criteriaSystematic reviewReported associationsHospital certificationProvider reimbursementOutcomesAssociationLimited associationCareQuality improvementCompliance
2010
Stroke: working toward a prioritized world agenda
Hachinski V, Donnan G, Gorelick P, Hacke W, Cramer S, Kaste M, Fisher M, Brainin M, Buchan A, Lo E, Skolnick B, Furie K, Hankey G, Kivipelto M, Morris J, Rothwell P, Sacco R, Smith S, Wang Y, Bryer A, Ford G, Iadecola C, Martins S, Saver J, Skvortsova V, Bayley M, Bednar M, Duncan P, Enney L, Finklestein S, Jones T, Kalra L, Kleim J, Nitkin R, Teasell R, Weiller C, Desai B, Goldberg M, Heiss W, Saarelma O, Schwamm L, Shinohara Y, Trivedi B, Wahlgren N, Wong L, Hakim A, Norrving B, Prudhomme S, Bornstein N, Davis S, Goldstein L, Leys D, Tuomilehto J. Stroke: working toward a prioritized world agenda. International Journal Of Stroke 2010, 5: 238-256. PMID: 20636706, PMCID: PMC3712839, DOI: 10.1111/j.1747-4949.2010.00442.x.Peer-Reviewed Original ResearchConceptsStroke careChronic disease prevention initiativeStroke-related informationEmergency stroke careDisease prevention initiativesPublic health communication strategiesConsequences of strokeRigorous clinical researchHealth communication strategiesStroke preventionStroke centersStroke unitClinical strokeSubclinical strokeBrain recoveryCerebrovascular diseaseStroke recoveryBrain healthPoststroke rehabilitationTelestroke networkClinical careHuman studiesEpidemiological disciplinesSurrogate assessmentStrokeStroke: Working Toward a Prioritized World Agenda
Hachinski V, Donnan G, Gorelick P, Hacke W, Cramer S, Kaste M, Fisher M, Brainin M, Buchan A, Lo E, Skolnick B, Furie K, Hankey G, Kivipelto M, Morris J, Rothwell P, Sacco R, Smith S, Wang Y, Bryer A, Ford G, Iadecola C, Martins S, Saver J, Skvortsova V, Bayley M, Bednar M, Duncan P, Enney L, Finklestein S, Jones T, Kalra L, Kleim J, Nitkin R, Teasell R, Weiller C, Desai B, Goldberg M, Heiss W, Saarelma O, Schwamm L, Shinohara Y, Trivedi B, Wahlgren N, Wong L, Hakim A, Norrving B, Prudhomme S, Bornstein N, Davis S, Goldstein L, Leys D, Tuomilehto J. Stroke: Working Toward a Prioritized World Agenda. Stroke 2010, 41: 1084-1099. PMID: 20498453, PMCID: PMC3712843, DOI: 10.1161/strokeaha.110.586156.Peer-Reviewed Original ResearchConceptsStroke careChronic disease prevention initiativeStroke-related informationEmergency stroke careDisease prevention initiativesPublic health communication strategiesConsequences of strokeRigorous clinical researchHealth communication strategiesStroke preventionStroke centersStroke unitClinical strokeSubclinical strokeBrain recoveryCerebrovascular diseaseStroke recoveryBrain healthPoststroke rehabilitationTelestroke networkClinical careHuman studiesEpidemiological disciplinesSurrogate assessmentStrokeStroke: Working toward a Prioritized World Agenda
Hachinski V, Donnan G, Gorelick P, Hacke W, Cramer S, Kaste M, Fisher M, Brainin M, Buchan A, Lo E, Skolnick B, Furie K, Hankey G, Kivipelto M, Morris J, Rothwell P, Sacco R, Smith S, Wang Y, Bryer A, Ford G, Iadecola C, Martins S, Saver J, Skvortsova V, Bayley M, Bednar M, Duncan P, Enney L, Finklestein S, Jones T, Kalra L, Kleim J, Nitkin R, Teasell R, Weiller C, Desai B, Goldberg M, Heiss W, Saarelma O, Schwamm L, Shinohara Y, Trivedi B, Wahlgren N, Wong L, Hakim A, Norrving B, Prudhomme S, Bornstein N, Davis S, Goldstein L, Leys D, Tuomilehto J. Stroke: Working toward a Prioritized World Agenda. Cerebrovascular Diseases 2010, 30: 127-147. PMID: 20516682, PMCID: PMC3221270, DOI: 10.1159/000315099.Peer-Reviewed Original ResearchConceptsStroke careChronic disease prevention initiativeStroke-related informationEmergency stroke careDisease prevention initiativesPublic health communication strategiesConsequences of strokeRigorous clinical researchHealth communication strategiesStroke preventionStroke centersStroke unitClinical strokeSubclinical strokeBrain recoveryCerebrovascular diseaseStroke recoveryBrain healthPoststroke rehabilitationTelestroke networkClinical careHuman studiesEpidemiological disciplinesSurrogate assessmentStroke
2008
Organizing regional stroke systems of care
Park S, Schwamm L. Organizing regional stroke systems of care. Current Opinion In Neurology 2008, 21: 43-55. PMID: 18180651, DOI: 10.1097/wco.0b013e3282f4304d.Peer-Reviewed Original ResearchConceptsStroke treatmentStroke systemsHospital-based stroke careMajor public health problemRegional stroke systemAcute stroke treatmentBetter patient outcomesPublic health problemCare delivery modelsContinuous quality improvement activitiesAcute stroke expertiseAir medical transportEmergency medical servicesHealth policy changesQuality improvement activitiesStroke survivalSecondary preventionStroke unitStroke careThrombolytic therapyPrimary preventionStroke expertisePatient outcomesStroke educationHealth problems