2025
Elevated initial blood kynurenine is associated with increased odds of post-stroke infection Kynurenine and post-stroke infection
Dylla L, Reisz J, Poisson S, Herson P, Sansing L, Monte A. Elevated initial blood kynurenine is associated with increased odds of post-stroke infection Kynurenine and post-stroke infection. Journal Of Stroke And Cerebrovascular Diseases 2025, 34: 108268. PMID: 40015349, DOI: 10.1016/j.jstrokecerebrovasdis.2025.108268.Peer-Reviewed Original ResearchConceptsPost-stroke infectionsAssociated with increased oddsTryptophan metabolitesHistory of diabetes mellitusEnd stage renal diseaseNIH Stroke Scale scoreConcentrations of kynurenineAcute ischemic stroke patientsMultivariate logistic regressionStage renal diseaseStroke Scale scoreCirculating kynurenineIschemic stroke onsetIschemic stroke patientsKynurenine concentrationsConcentrations of tryptophanEmergency department admissionsKynurenic acidDiabetes mellitusMortality of ischemic strokeRenal diseaseTryptophan metabolismOdds ratioQuinolinic acidImmune response
2023
Response to: Acute ischemic stroke and cardioemboli: Does sex matter?
Higgins H, Chen L, Ravare B, Jeppson K, Bina H, Herson P, Monte A, Poisson S, Dylla L. Response to: Acute ischemic stroke and cardioemboli: Does sex matter? The American Journal Of Emergency Medicine 2023, 74: 170-171. PMID: 37867013, PMCID: PMC10792528, DOI: 10.1016/j.ajem.2023.10.014.Peer-Reviewed Original ResearchSex differences in acute ischemic stroke presentation are a matter of infarct location
Higgins H, Chen L, Ravare B, Jeppson K, Bina H, Herson P, Monte A, Poisson S, Dylla L. Sex differences in acute ischemic stroke presentation are a matter of infarct location. The American Journal Of Emergency Medicine 2023, 74: 95-99. PMID: 37802001, PMCID: PMC10843056, DOI: 10.1016/j.ajem.2023.09.046.Peer-Reviewed Original ResearchMeSH KeywordsBrain IschemiaFemaleHumansInfarctionIschemic StrokeMaleRetrospective StudiesSex CharacteristicsStrokeConceptsEmergency medical servicesMultivariate logistic regressionStroke symptomsFrequency of patient presentationLogistic regressionStroke screening toolElectronic health recordsRecognition of strokeAcute ischemic strokeInfarct locationClassic symptomsEmergency department treatmentDistribution of strokeIschemic strokeIschemic stroke presentingHealth recordsRetrospective cohort studyMedical servicesUnilateral weaknessAnterior circulation infarctionCohort studyScreening toolStroke presentationEtiology of strokePosterior circulation infarction
2019
Prehospital supplemental oxygen for acute stroke – A retrospective analysis
Dylla L, Adler D, Abar B, Benesch C, Jones C, O'Banion M, Cushman J. Prehospital supplemental oxygen for acute stroke – A retrospective analysis. The American Journal Of Emergency Medicine 2019, 38: 2324-2328. PMID: 31787444, PMCID: PMC7231670, DOI: 10.1016/j.ajem.2019.11.002.Peer-Reviewed Original ResearchConceptsRespiratory complicationsNeurological outcomeSupplemental oxygenRetrospective analysisRate of respiratory complicationsPrehospital oxygen saturationAdministration of supplemental oxygenAssociated with neurological outcomeMultivariate logistic regressionAcademic comprehensive stroke centerSubjects' medical records.Comprehensive stroke centerClinical characteristicsRespiratory compromiseAcute stroke patientsRetrospective natureEligible patientsNo significant increaseImprove stroke outcomesMedical recordsGuidelines-Stroke registryOxygen saturationPenumbral tissuePotential confoundersControl):
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