Differences in expression, actions and cocaine regulation of two isoforms for the brain transcriptional regulator NAC1
Korutla L, Wang P, Lewis D, Neustadter J, Stromberg M, Mackler S. Differences in expression, actions and cocaine regulation of two isoforms for the brain transcriptional regulator NAC1. Neuroscience 2002, 110: 421-429. PMID: 11906783, DOI: 10.1016/s0306-4522(01)00518-8.Peer-Reviewed Original ResearchConceptsBTB/POZ proteinPOZ proteinShort isoformDNA binding domainsPost-transcriptional processingSemi-quantitative reverse transcription-polymerase chain reaction analysisPeripheral tissuesRat brainTranscriptional repressionSubnuclear localizationTranscription-polymerase chain reaction analysisBinding domainsReverse transcription-polymerase chain reaction analysisReporter systemCell cycleCocaine-induced locomotionRat nucleus accumbensWestern blot analysisTranscriptionAmino acidsIsoformsProteinChain reaction analysisBlot analysisNeuronal function