1996
Inhibition of Vesicular Stomatitis Virus Replication by Epidermal Growth Factor in Human Epidermoid A-431 Cells
Korutla L, Kumar R. Inhibition of Vesicular Stomatitis Virus Replication by Epidermal Growth Factor in Human Epidermoid A-431 Cells. Biochemical And Biophysical Research Communications 1996, 220: 670-674. PMID: 8607823, DOI: 10.1006/bbrc.1996.0462.Peer-Reviewed Original ResearchConceptsEpidermal growth factorVesicular stomatitis virusInfectious viral particle productionAnti-EGF receptor monoclonal antibodyGrowth factorObserved antiviral effectReceptor monoclonal antibodyVesicular stomatitis virus replicationHuman epidermoid AVSV protein synthesisAntiviral effectViral particle productionAntiviral actionVSV infectionPrior treatmentViral protein synthesisVSV replicationPostinfection treatmentVirus replicationMonoclonal antibodiesInhibitory effectEarly effectsProtein synthesisSignificant inhibitionCell protection
1995
Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin
Korutla L, Cheung J, Medelsohn J, Kumar R. Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin. Carcinogenesis 1995, 16: 1741-1745. PMID: 7634398, DOI: 10.1093/carcin/16.8.1741.Peer-Reviewed Original ResearchConceptsGrowth stimulatory pathwaysTumor cell growthTime-dependent mannerAnti-proliferative strategyTyrosine phosphorylationEpidermal growth factorEpidermal growth factor receptor tyrosine phosphorylationCurcumin treatmentActivation of EGFCalcium releaseStimulatory pathwayReceptor tyrosine phosphorylationTreatment of cellsEGF receptor phosphorylationKinase inhibitorsGrowth factorSurface expressionReceptor phosphorylationHuman EGFCurcuminEGFInhibition of EGFPotent inhibitorActivationCell growth