2025
Effect of Sodium-Glucose Cotransporter-2 Inhibitors on the Progression of Aortic Stenosis
Shah T, Zhang Z, Shah H, Fanaroff A, Nathan A, Parise H, Lutz J, Sugeng L, Bellumkonda L, Redfors B, Omerovic E, Petrie M, Vora A, Fiorilli P, Kobayashi T, Ahmad Y, Forrest J, Giri J, Herrmann H, Lansky A. Effect of Sodium-Glucose Cotransporter-2 Inhibitors on the Progression of Aortic Stenosis. JACC Cardiovascular Interventions 2025, 18: 738-748. PMID: 39985508, DOI: 10.1016/j.jcin.2024.11.036.Peer-Reviewed Original ResearchSodium-glucose cotransporter-2 inhibitorsCotransporter-2 inhibitorsAortic stenosisEffects of sodium-glucose cotransporter-2 inhibitorsProgression of aortic stenosisBaseline AS severityAssociated with slower progressionEchocardiographic follow-upRetrospective electronic medical record dataAortic valve sclerosisDisease-related morbidityChronic kidney diseaseSGLT2i usageRates of diabetesSevere ASAS severityEjection fractionFollow-upPrimary outcomeGt;1 yearKidney diseaseMedical record dataYale New Haven Health SystemPatientsObservational studyElevated Systolic Blood Pressure and Hemodynamic Parameters in Patients with Aortic Stenosis Undergoing Echocardiography in Real-World Practice
Singh J, Reinhardt S, Hur D, Sugeng L, Akintoye E, Lombo B, Bellumkonda L, Shkolnik E, McNamara R, Faridi K. Elevated Systolic Blood Pressure and Hemodynamic Parameters in Patients with Aortic Stenosis Undergoing Echocardiography in Real-World Practice. Journal Of The American Society Of Echocardiography 2025 PMID: 39884444, DOI: 10.1016/j.echo.2025.01.010.Peer-Reviewed Original Research
2024
High- versus low-gradient aortic stenosis: Is our evaluation limited by aorto-mitral angle on cardiovascular CT?
See C, Kim Y, Park J, Wang Y, Reinhardt S, Shkolnik E, Faridi K, Lombo B, Bellumkonda L, McNamara R, Sugeng L, Hur D. High- versus low-gradient aortic stenosis: Is our evaluation limited by aorto-mitral angle on cardiovascular CT? International Journal Of Cardiology 2024, 409: 132174. PMID: 38754590, DOI: 10.1016/j.ijcard.2024.132174.Peer-Reviewed Original ResearchNormal-flow low-gradientAortic valve areaTranscatheter AV replacementParadoxical low-flow low-gradientCardiovascular CTTransthoracic echocardiogramCalcium scoreAS patientsDiagnosis of severe ASLow-gradient aortic stenosisHG-AS patientsLG-AS patientsLow-flow low-gradientAorto-mitral angleAortic valve (AV) stenosisLG-ASPLFLG-ASAV replacementSevere ASConsecutive patientsAortic stenosisValve areaAS phenotypeClinical managementEchocardiogramThree-dimensional (3D) Right Ventricular Surface Strain Computed From 3D Echocardiography Correlates With RVEF and Reveals Differences in Deformation Based on Severity of Pulmonary Arterial Hypertension Symptoms
Oakland H, Bellumkonda L, Sugeng L, Joseph P, Izzi D, Zalik F, McCabe S, Raza A, Amendola R, Heerdt P, Singh I, Hunter K. Three-dimensional (3D) Right Ventricular Surface Strain Computed From 3D Echocardiography Correlates With RVEF and Reveals Differences in Deformation Based on Severity of Pulmonary Arterial Hypertension Symptoms. 2024, a7381-a7381. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a7381.Peer-Reviewed Original Research
2023
Variation in Reader-Reported Severity of Paradoxical Low-Flow Low-Gradient Aortic Stenosis
Shah N, Sugeng L, Zhang Z, Wang K, McNamara R, Agarwal V, Hur D, Lombo B, Bellumkonda L, Mankbadi M, Basem Dajani A, Forrest J, Krumholz H, Reinhardt S, Velazquez E, Faridi K. Variation in Reader-Reported Severity of Paradoxical Low-Flow Low-Gradient Aortic Stenosis. Journal Of The American Society Of Echocardiography 2023, 37: 466-467. PMID: 37995937, DOI: 10.1016/j.echo.2023.11.014.Peer-Reviewed Original Research
2022
TCT-394 Conformal CLAAS LAAO Device Seal at 45 Days: Initial Echo Core Lab Assessment in 50 Patients
Nair D, Sugeng L, Kim J, Coylewright M, Doshi S, Ellis C, Szerlip M, Choo J, Reddy V, Bellumkonda L, Kaplan A, Gray W. TCT-394 Conformal CLAAS LAAO Device Seal at 45 Days: Initial Echo Core Lab Assessment in 50 Patients. Journal Of The American College Of Cardiology 2022, 80: b159. DOI: 10.1016/j.jacc.2022.08.463.Peer-Reviewed Original Research
2020
TCT CONNECT-184 Impact of Sex and Timing of Impella Support in Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock
Shah T, Chou J, Grines C, Chieffo A, Bellumkonda L, Sugeng L, Ghiu I, Moses J, O'Neill W, Lansky A. TCT CONNECT-184 Impact of Sex and Timing of Impella Support in Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock. Journal Of The American College Of Cardiology 2020, 76: b78-b79. DOI: 10.1016/j.jacc.2020.09.197.Peer-Reviewed Original ResearchA Systematic Review of Cardiogenic Shock in the Setting of Severe Aortic Stenosis: Prevalence, Management, and Outcomes
Essa M, Essa M, Berardi C, Aneni E, Fleming J, Trejo-Paredes M, Bellumkonda L, F. Faridi K, Sugeng L. A Systematic Review of Cardiogenic Shock in the Setting of Severe Aortic Stenosis: Prevalence, Management, and Outcomes. American Journal Of Cardiovascular Research 2020, 1-9. DOI: 10.31487/nl.ajcr.2020.01.02.Peer-Reviewed Original ResearchBalloon aortic valvuloplastySevere aortic stenosisSurgical valve replacementCardiogenic shockAortic stenosisSystematic reviewCommon valvular heart diseaseProcedure-related complicationsValvular heart diseaseTranscatheter aortic valveHospital mortalityAortic valvuloplastyValve replacementPrimary outcomeCirculatory supportFatal conditionAortic valveHeart diseaseStudy protocolBetter outcomesPatientsMedical emergencyStenosisAdditional outcomesMortality
2019
A Systematic Review of Cardiogenic Shock in the Setting of Severe Aortic Stenosis: Prevalence, Management and Outcomes
Essa M, Aneni E, Bernardi C, Fleming J, Paredes M, Frumento K, Abdelmessih M, Sugeng L, Bellumkonda L. A Systematic Review of Cardiogenic Shock in the Setting of Severe Aortic Stenosis: Prevalence, Management and Outcomes. Journal Of Cardiac Failure 2019, 25: s51. DOI: 10.1016/j.cardfail.2019.07.143.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementBalloon aortic valvuloplastyMechanical circulatory supportSurgical valve replacementAortic stenosisValve replacementPrevalence of ASCommon valvular heart diseaseMechanical circulatory support devicesCardiogenic shock managementSevere aortic stenosisAortic valve replacementProcedure-related complicationsValvular heart diseaseCirculatory support devicesHospital mortalityAortic valvuloplastyCardiogenic shockPrimary outcomeValve interventionCirculatory supportFatal conditionShock managementHeart diseaseStudy protocolLVAD Survival May Be Predicted by Preoperative Lymphopenia
Stawiarski K, Agboola O, Jacoby D, Bellumkonda L, Sugeng L, Ahmad T, Chen M, McCloskey G, Geirsson A, Anwar M, Bonde P. LVAD Survival May Be Predicted by Preoperative Lymphopenia. The Journal Of Heart And Lung Transplantation 2019, 38: s63-s64. DOI: 10.1016/j.healun.2019.01.142.Peer-Reviewed Original ResearchAbsolute lymphocyte countCause mortalityLVAD patientsImmune modulator therapyImpact of lymphopeniaImportant prognostic indicatorCells/ÎĽL.Kaplan-Meir plotsLog-rank statisticsPhysiologic stress responseLVAD survivalPreoperative lymphopeniaSplanchnic congestionCox modellingLymphocyte countLymphocyte levelsLymphopenic patientsUnadjusted survivalWorse survivalHeart failurePrognostic roleSerum sodiumSingle centerPatient groupLVAD therapyChloride Homeostasis in End Stage Heart Failure and LVAD Recipients
Stawiarski K, Agboola O, Jacoby D, Bellumkonda L, Ahmad T, Sugeng L, Chen M, McCloskey G, Geirsson A, Anwar M, Bonde P. Chloride Homeostasis in End Stage Heart Failure and LVAD Recipients. The Journal Of Heart And Lung Transplantation 2019, 38: s382-s383. DOI: 10.1016/j.healun.2019.01.974.Peer-Reviewed Original ResearchSerum chloride levelsChloride homeostasisLVAD patientsHeart failureLVAD therapyEnd-stage heart failureCardio-renal axisChronic heart failureStage heart failureChloride levelsLong-term survivalKaplan-Meir plotsLog-rank statisticsL riseCause mortalityLVAD recipientsWorse survivalSingle centerNeurohormonal responsesPrognostic implicationsPrognostic valueLVAD implantsRetrospective analysisGroup ACox modelLYMPHOPENIA AS A PREDICTOR FOR SURVIVAL IN LVAD PATIENTS
Stawiarski K, Agboola O, Jacoby D, Ali A, Bellumkonda L, Ahmad T, Sugeng L, McCloskey G, Chen M, Geirsson A, Bonde P, Anwer M. LYMPHOPENIA AS A PREDICTOR FOR SURVIVAL IN LVAD PATIENTS. Journal Of The American College Of Cardiology 2019, 73: 802. DOI: 10.1016/s0735-1097(19)31409-3.Peer-Reviewed Original Research
2018
(787) Gender and Diastolic Dysfunction May be the Driver of Failure of Myocardial Recovery Following LVAD Implantation
Stawiarski K, Zogg C, Park J, Jacoby D, Bellumkonda L, Chen M, Ahmad T, Testani J, McCloskey G, Sugeng L, Bonde P. (787) Gender and Diastolic Dysfunction May be the Driver of Failure of Myocardial Recovery Following LVAD Implantation. The Journal Of Heart And Lung Transplantation 2018, 37: s311. DOI: 10.1016/j.healun.2018.01.790.Peer-Reviewed Original Research
2016
PM240 The Use of Left Ventricular Strain as a Non-Invasive Alternative to Surveillance Endomyocardial Biopsy
Ganeshan R, Lombo B, Bellumkonda L, Lin B, Sugeng L. PM240 The Use of Left Ventricular Strain as a Non-Invasive Alternative to Surveillance Endomyocardial Biopsy. Global Heart 2016, 11: e111. DOI: 10.1016/j.gheart.2016.03.388.Peer-Reviewed Original Research
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