2024
Sex-driven variability in TSPO-expressing microglia in MS patients and healthy individuals
Laaksonen S, Saraste M, Nylund M, Hinz R, Snellman A, Rinne J, Matilainen M, Airas L. Sex-driven variability in TSPO-expressing microglia in MS patients and healthy individuals. Frontiers In Neurology 2024, 15: 1352116. PMID: 38445263, PMCID: PMC10913932, DOI: 10.3389/fneur.2024.1352116.Peer-Reviewed Original ResearchDistribution volume ratioNormal-appearing white matterMale MS patientsCortical gray matterMS patientsPositron emission tomographyTSPO bindingMultiple sclerosisDisease progressionHealthy individualsClinical disease progressionWhole-brainBrain positron emission tomographySex differencesMales compared to femalesFemale patientsHealthy womenDisability progressionGreater likelihoodGray matterHealthy controlsStudy cohortFemale controlsEmission tomographyBrain
2022
Serum Neurofilament Light Associates with Microglial Activation in the Multiple Sclerosis Brain (S26.010)
Saraste M, Matilainen M, Sucksdorff M, Leppert D, Kuhle J, Airas L. Serum Neurofilament Light Associates with Microglial Activation in the Multiple Sclerosis Brain (S26.010). Neurology 2022, 98 DOI: 10.1212/wnl.98.18_supplement.2588.Peer-Reviewed Original Research
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