2025
Defining Thresholds for Meaningful Health Status Changes Following Transfemoral Carotid Artery Stenting
Kluger J, Romain G, Mena‐Hurtado C, Grubman S, Pajarillo C, Cleman J, Scierka L, Smolderen K. Defining Thresholds for Meaningful Health Status Changes Following Transfemoral Carotid Artery Stenting. Catheterization And Cardiovascular Interventions 2025, 105: 927-937. PMID: 39789704, DOI: 10.1002/ccd.31410.Peer-Reviewed Original ResearchConceptsMinimal clinically important differenceHealth status changesHealth statusSF-36Visual analog scaleEQ-5DDistribution-based MCIDPhysical component scoreCarotid artery stentingDisease-specific instrumentHealth status improvementTransfemoral carotid artery stentingSymptom statusClinically important differenceTF-CASStatus changesGeneric instrumentsArtery stentingRegistry dataComponent scoresImportant differencePatients no changeStatus improvementAsymptomatic carotid stenosisHealth
2024
Twelve-month health status response after peripheral vascular intervention for femoropopliteal lesions using Zilver PTX databases focusing on the role of preprocedural health status, comorbid risks, and global setting
Smolderen K, Romain G, Cleman J, Callegari S, Peri-Okonny P, Mena-Hurtado C. Twelve-month health status response after peripheral vascular intervention for femoropopliteal lesions using Zilver PTX databases focusing on the role of preprocedural health status, comorbid risks, and global setting. Journal Of Vascular Surgery 2024, 81: 210-220.e7. PMID: 39214426, DOI: 10.1016/j.jvs.2024.08.035.Peer-Reviewed Original ResearchMinimal clinically important differenceEQ-5D indexHealth statusPeripheral vascular interventionsPeripheral arterial diseaseEQ-5DNon-respondersValue-based careEuroQol-5D-3LClinically important differenceSecondary data analysisFemoropopliteal peripheral vascular interventionsStable health statusLogistic regression modelsArtery diseaseSymptomatic peripheral arterial diseaseStatus responseTailored resourcesVascular interventionsSingle-arm studyImportant differenceCarotid artery diseaseComorbidity riskEnrolling centersPatient characteristics
2022
Health status and cognitive function for risk stratification in chronic coronary and peripheral artery disease.
Smolderen K, Mena-Hurtado C, Eikelboom J, Bosch J, Xie F, Ramasundarahettige C, Bhatt D, Anand S. Health status and cognitive function for risk stratification in chronic coronary and peripheral artery disease. European Journal Of Preventive Cardiology 2022, 30: 535-545. PMID: 36444513, DOI: 10.1093/eurjpc/zwac282.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseDigit Symbol Substitution TestVisual analog scaleEQ visual analogue scaleHealth statusLimb eventsCAD cohortCognitive functionArtery diseaseEQ-5DHierarchical Cox regression modelsMajor adverse cardiovascular eventsStable coronary artery diseaseAdverse cardiovascular eventsPeripheral artery diseasePopulation attributable riskCox regression modelOverall health statusCognitive function assessmentCOMPASS trialPAD cohortCardiovascular eventsPAD patientsRisk stratificationAnalog scale
2020
Association of Health Status Scores With Cardiovascular and Limb Outcomes in Patients With Symptomatic Peripheral Artery Disease: Insights From the EUCLID (Examining Use of Ticagrelor in Symptomatic Peripheral Artery Disease) Trial
Rymer JA, Mulder H, Smolderen KG, Hiatt WR, Conte MS, Berger JS, Norgren L, Mahaffey KW, Baumgartner I, Fowkes FG, Katona BG, Rockhold F, Jones WS, Patel MR. Association of Health Status Scores With Cardiovascular and Limb Outcomes in Patients With Symptomatic Peripheral Artery Disease: Insights From the EUCLID (Examining Use of Ticagrelor in Symptomatic Peripheral Artery Disease) Trial. Journal Of The American Heart Association 2020, 9: e016573. PMID: 32924754, PMCID: PMC7792388, DOI: 10.1161/jaha.120.016573.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesDouble-Blind MethodFemaleHealth Status IndicatorsHumansLower ExtremityMaleMiddle AgedOutcome Assessment, Health CarePeripheral Arterial DiseasePlatelet Aggregation InhibitorsQuality of LifeSurveys and QuestionnairesSymptom AssessmentTicagrelorVascular Surgical ProceduresVisual Analog ScaleConceptsMajor adverse cardiovascular eventsMajor adverse limb eventsAdverse cardiovascular eventsAdverse limb eventsLower extremity revascularizationPeripheral artery diseaseCardiovascular eventsHealth status instrumentsLimb eventsEUCLID trialVAS scoresArtery diseaseEQ-5DQuestionnaire scoresSubsequent major adverse cardiovascular eventsLow ankle-brachial indexSymptomatic peripheral artery diseaseLower extremity revascularization proceduresBaseline EQ-5DAnkle-brachial indexHealth status scoresEQ-5D scoresHealth status measurementHealth status changesSubsequent end points
2008
Clinical validity of a disease-specific health status questionnaire: The Peripheral Artery Questionnaire
Hoeks SE, Smolderen KG, Reimer W, Verhagen HJ, Spertus JA, Poldermans D. Clinical validity of a disease-specific health status questionnaire: The Peripheral Artery Questionnaire. Journal Of Vascular Surgery 2008, 49: 371-377. PMID: 19028064, DOI: 10.1016/j.jvs.2008.08.089.Peer-Reviewed Original ResearchMeSH KeywordsAgedDisability EvaluationFactor Analysis, StatisticalFemaleHealth Status IndicatorsHumansIntermittent ClaudicationMaleNetherlandsPain MeasurementPatient SatisfactionPeripheral Arterial DiseasePredictive Value of TestsPsychometricsRecovery of FunctionReproducibility of ResultsRetrospective StudiesSensitivity and SpecificitySeverity of Illness IndexSurveys and QuestionnairesTreatment OutcomeVascular Surgical ProceduresWalkingConceptsPeripheral Artery QuestionnairePeripheral arterial diseaseDisease-specific Peripheral Artery QuestionnaireClear dose-response relationPAQ summary scoreDose-response relationClinical indicesClinical validitySummary scoresPAD patientsEQ-VASEQ-5DHealth statusLee Cardiac Risk IndexSymptomatic peripheral arterial diseaseEuroQol visual analogue scaleBaseline clinical indicesConsecutive PAD patientsGeneric EQ-5DSeverity of claudicationCardiac Risk IndexDisease-specific health status questionnaireEQ-5D indexHealth Status QuestionnairePatient-centered outcomes
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