2019
An immunogenic NSCLC microenvironment is associated with favorable survival in lung adenocarcinoma
Givechian KB, Garner C, Benz S, Song B, Rabizadeh S, Soon-Shiong P. An immunogenic NSCLC microenvironment is associated with favorable survival in lung adenocarcinoma. Oncotarget 2019, 10: 1840-1849. PMID: 30956762, PMCID: PMC6442995, DOI: 10.18632/oncotarget.26748.Peer-Reviewed Original ResearchLung squamous cell carcinomaNon-small cell lung cancerSquamous cell carcinomaLung adenocarcinomaTumor microenvironmentCell carcinomaLung cancerFavorable patient survivalImmune-excluded tumorsCell lung cancerInflamed tumor microenvironmentImmune checkpoint marker expressionLung adenocarcinoma subtypesMajor NSCLC subtypesAnti-tumor immunogenicityImmunological mechanismsFavorable survivalPrognostic effectAdenocarcinoma subtypePatient survivalSurvival outcomesNSCLC subtypesImmune cellsNSCLC microenvironmentLUSC samples
2018
CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma
Givechian KB, Garner C, Garban H, Rabizadeh S, Soon-Shiong P. CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma. Oncotarget 2018, 9: 29743-29752. PMID: 30038717, PMCID: PMC6049856, DOI: 10.18632/oncotarget.25701.Peer-Reviewed Original ResearchBladder urothelial carcinomaPoor overall survivalUrothelial carcinomaOverall survivalBladder urothelial carcinoma patientsUrothelial carcinoma patientsPlatinum-based therapyMechanisms of chemoresistancePatient tumor samplesRepair genesSystemic chemotherapyFavorable survivalNucleotide excision repair genesWorse survivalCarcinoma patientsPoor survivalTherapeutic strategiesTherapy resistancePyrimidine synthesis pathwayRepair processClinical targetsTumor samplesPatientsCarcinomaDNA repair genes
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply