2024
Perioperative Pain Management: An Update on Pharmacology with a Special Focus on the Opioid Tolerant Elderly
Chow R, Rajput K. Perioperative Pain Management: An Update on Pharmacology with a Special Focus on the Opioid Tolerant Elderly. Current Anesthesiology Reports 2024, 15: 6. DOI: 10.1007/s40140-024-00656-7.Peer-Reviewed Original ResearchElderly patientsOpioid toleranceChronic painPain managementModerate to high-risk patientsIncreasing use of opioidsOpioid-tolerant patientsSide effects of sedationOpioid sparing effectDoses of opioidsHigh-risk patientsUse of opioidsDrug-drug interactionsChronic opioidsOpioid requirementsTolerant patientsMultimodal analgesicsEffects of sedationPerioperative painRespiratory depressionHome dosePreexisting comorbiditiesPain surgeryRegional anestheticsPerioperative period
2021
Patterns of Use of Opioid Sparing Adjuncts for Perioperative Pain Management of Patients on Chronic Opioids.
Rajput K, Reid CB, Yanez D, Shiwlochan D, Ohanyan S, Chow R. Patterns of Use of Opioid Sparing Adjuncts for Perioperative Pain Management of Patients on Chronic Opioids. Pain Physician 2021, 24: 577-586. PMID: 34793645.Peer-Reviewed Original ResearchConceptsChronic opioid useNarcotic scorePostoperative opioid usePerioperative pain managementOpioid useMultimodal analgesicsChronic opioidsRegional anesthesiaSurgical factorsPredictors of usePain managementHigher oddsSingle-center retrospective observational studyTertiary care academic hospitalIntraoperative opioid useOpioid-sparing adjunctsPerioperative pain controlRetrospective observational studyOutcomes of interestMean MMEMore MMEsMorphine equivalentsOpioid doseComorbidity indexIntraoperative opioids
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