2016
RNA G-quadruplexes are globally unfolded in eukaryotic cells and depleted in bacteria
Guo J, Bartel D. RNA G-quadruplexes are globally unfolded in eukaryotic cells and depleted in bacteria. Science 2016, 353: aaf5371-aaf5371. PMID: 27708011, PMCID: PMC5367264, DOI: 10.1126/science.aaf5371.Peer-Reviewed Original ResearchConceptsRNA G-quadruplexesEukaryotic cellsG-quadruplexStable four-stranded structuresG-quadruplexes in vitroG-quadruplex-forming sequencesPosttranscriptional gene regulationG-quadruplex-forming regionsFour-stranded structuresBacterial transcriptomesRNA regionsGene regulationEscherichia coliImpaired translationRNABacteriaCellsIn vitroEukaryotesTranscriptomeSequenceMachineryRegionRegulation
2013
Chapter 3 Active DNA Demethylation and 5-Hydroxymethylcytosine
Guo J, Ming G, Song H. Chapter 3 Active DNA Demethylation and 5-Hydroxymethylcytosine. 2013, 69-83. DOI: 10.1016/b978-0-12-391494-1.00003-3.Peer-Reviewed Original ResearchActive DNA demethylationDNA demethylationRegulation of gene expression programsCytosine C5-methylationCharacterized epigenetic modificationDNA base 5-hydroxymethylcytosineGene expression programsEukaryotic cellsDNA methylationEpigenetic modificationsMammalian nervous systemDynamic regulationMolecular mechanismsExpression programsC5-methylationDemethylationDNANervous systemPathological conditionsCytosine
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