Joseph Brennan, MD, BS
Professor of Clinical Medicine (Cardiovascular Medicine); Firm Chief- Coronary Intensive Care Unit (CICU), Internal Medicine; Director, Interventional Cardiology Fellowship Program, Internal Medicine; Medical Director, Coronary Intensive Care Unit, Yale-New Haven Hospital, Yale Medicine; Director, Inpatient Cardiology Services, Yale Medicine
Biography
Research & Publications
Patient Care
News
Locations
Appointments
Biography
I have been a member of the Section of Cardiovascular Medicine since completion of Cardiology fellowship in 1989. My primary interest has been clinical cardiology particularly in the areas of both Intensive Care Cardiology (serving as Medical Director of the CICU) as well as Interventional cardiology (serving as the Fellowship Director of the Interventional Cardiology Fellowship for the past 20 yrs). I have been the recipient of innumerable teaching awards both within the Yale Medical School as ell as the Department of Medicine/Section of Cardiology.
Education & Training
- FellowYale New Haven Hospital (1990)
- Chief ResidentYale New Haven Hospital (1987)
- ResidentYale New Haven Hospital (1986)
- MDMedical College of Virginia (1983)
- BSCollege of William and Mary, Biology (1978)
Activities
- CRTWashington, United States 2019Speaker- Fellowship Directors Symposium
- Physician EducationHavana, Cuba; Saint Petersburg, Russia; Dalian, China; Moschi, Tanzania; Dechapelle, Haiti (1985-2016)Have served in multiple areas around the world both during medical residency as well as a faculty member
Honors & Recognition
| Award | Awarding Organization | Date |
|---|---|---|
| Fred Kantor Internal Medicine Residency Teaching Award | Yale University | 2020 |
| Leonard Tow Humanism in Medicine Award | 2017 | |
| Teacher of the Year Yale Primary Care Residency | 2015 | |
| Master Clinician Yale Primary Care Residency | 2015 | |
| Consultant of the Year Given by ED Residents | 2013 | |
| Teacher of the Year Cardiology Section | 2012 | |
| Nurses Choice Award | 2012 | |
| Teacher of the Year Yale Traditional Internal Medicine Residency | 2011 | |
| "Top Docs" | Connecticut Magazine | 2010, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019 |
| Fellow, Society of Coronary Angiography and Interventions (SCAI) | 2005 | |
| Connecticut State Medical Society (CSMS) | 2005 | |
| Inaugaral Faculty Award for Clinical Care- Dept. of Internal Medicine | 2004 | |
| Society of Distinguished Teachers- Yale University School of Medicine | Yale University | 2000 |
| Outstanding House Staff Award- Given by Graduating Medical School Class (YSM) | 1987 | |
| Alpha Omega Alpha- Medical Honor Society | VCU/MCV | 1982 |
| Phi Beta Kappa | The College of William and Mary | 1976 |
Professional Service
| Organization | Role | Date |
|---|---|---|
| Department of Internal Medicine | Facilitator/participant in Department of Internal Medicine's Medical Error Disclosure and Critical Conversations Panel. | 2019 - Present |
| Department of Internal Medicine-Section of Cardiovascular Disease | Served as member of a clinical redesign committee within the Section of Cardiovascular Disease which had been tasked to redesign the large inpatient cardiac service. | 2018 - 2019 |
| Department of Internal Medicine-RISE (Resilience,Innovation and Sustainable Excellence) Faculty | Discussant/Presenter/Facilitator at Workshops for new "hires" in Department of Internal Medicine at New Faculty Orientation. | 2018 - Present |
| Clinical Events Committee- LAAO Registry. ClinicalTrials.gov Identifier: NCT02699957 | Chair of committee to adjudicate events The Left Atrial Appendage Occlusion Registry (LAAO Registry™) is designed to assess the prevalence, demographics, management, and outcomes of patients undergoing percutaneous and epicardial based left atrial appendage occlusion procedures to reduce the risk of stroke. Patient-level data will be submitted by participating hospitals on a quarterly basis to the American College of Cardiology Foundation's National Cardiovascular Data Registry (NCDR). The primary aims of the LAAO Registry are to optimize the outcomes and management of patients through the implementation of evidence-based guideline recommendations in clinical practice, facilitate efforts to improve the quality and safety for patients undergoing percutaneous and epicardial based left atrial appendage procedures, investigate novel quality improvement methods and provide risk-adjusted assessment of patients for comparison with nationwide NCDR data. | 2018 - Present |
| Clinical Event Committee-REFLECT Trial. ClinicalTrials.gov Identifier: NCT02536196 | Serving as member of Clinical Event Committee (CEC) for REFLECT Trial, adjudicating all outcome events for this large trial.The Keystone Heart TriGuard™ HDH is an aortic embolism deflection device intended to reduce the amount of embolic material that may enter the carotid, subclavian, and vertebral arteries during transcatheter heart valve implantation. The objective of the study is to assess the safety and efficacy of the TriGuard™ HDH embolic deflection device in patients undergoing transcatheter aortic valve implantation (TAVI), in comparison with an active control group of patients undergoing unprotected TAVI. | 2018 - 2019 |
| Clinical Events Committee-YALE NeuroTAVR - Neurological Complications of Contemporary Unprotected TAVR (Yale Neuro TAVR). Sponsor: Keystone Heart. ClinicalTrials.gov Identifier: NCT02073864. A prospective, multi-center study enrolling a minimum of 20 up to a maximum of 80 patients at up to six (6) investigational sites in the United States and European Union. | Member, Clinical Events Committee to adjudicate neurologic and other clinical events associated with TAVR. | 2017 - Present |
| Clinical Events Committee-BIOHELIX I. Bare Metal Stent Study. Sponsor: Biotronik. ClinicalTrials.gov Identifier: NCT01612767 | Adjudicated end point and clinical events for the investigational BIOTRONIK PRO-Kinetic Energy stent in subjects with atherosclerotic disease of native coronary arteries | 2017 - 2018 |
| Clinical Events Committee-Disrupt CAD I - Prospective Multi-Center, Single Arm Study of the Shockwave Coronary Rx Lithoplasty® System in Coronary Arteries Lithoplasty Study. Sponsor: Shockwave Medical Inc, ClinicalTrials.gov Identifier: NCT02650128. | Member, Clinical Events Committee to adjudicate events related to Lithoplasty device in coronary arteries. | 2017 - 2018 |
| Hearts Around the World | Served as physician liaison in Havana, Cuba | 2016 |
| Clinical Events Committee-RESTORE II Trial-ReZolve2™ Sirolimus-Eluting Bioresorbable Coronary Scaffold. Sponsor: REVA Medical. Clinical Trials.gov Identifier: NCT01845311. A prospective, multi-center, safety and performance study with a study population consisting of patients with clinical evidence of myocardial ischemia or a positive functional study. A maximum of 125 patients were to be enrolled into the study | Member, Clinical Events Committee to adjudicate clinical events in study invoving a bioabsorbable coronary scaffold. | 2016 - Present |
| WTNH New Haven Channel 8 | Presenter/Speaker | 2016 |
| Clinical Events Committee-SHOCKWAVE Coronary Rx Lithoplasty Study. Sponsor: Shockwave Medical Inc, ClinicalTrials.gov Identifier: NCT02650128 | Adjudicated end point and clinical events for Prospective, multi-center, single arm study designed to evaluate the safety and performance of the Shockwave Coronary Rx Lithoplasty® System to treat calcified lesions in the coronary arteries for the purpose of enhancing the placement of stents and reducing the ultimate residual stenosis. | 2016 - 2018 |
| Clinical Events Committee-FANTOM II Trial: FANTOM Sirolimus-Eluting Bioresorbable Coronary Scaffold. Sponsor: REVA Medical. ClinicalTrials.gov Identifier: NCT02539966 | Adjudicated end point and clinical events for Fantom Bioresorbable Coronary Scaffold in native coronary arteries | 2015 - 2017 |
| Yale University School of Medicine, Department of Internal Medicine | Member of Department of Medicine's Clinical Chiefs/Directors Committee- met quarterly. | 2015 - 2019 |
| Yale New Haven Hospital-ICU Leadership Committee | ICU leadership Committee | 2015 - Present |
| Yale University School of Medicine- Department of Internal Medicine/Section of Cardiovascular Disease. | Member of the Section of Cardiovascular Medicine' s Clinical Competency Committee (CCC). | 2015 - Present |
| Clinical Event Committee-ABLATE Trial (Atherectomy by Laser Ablation With Turbo-Elite (ABLATE) Sponsor: Spectranetics Corporation. ClinicalTrials.gov Identifier: NCT02307370 | Chair of Clinical events Committee for trial employing Spectranetics Laser treatment of PAD of infra-inguinal arteries. | 2014 - 2017 |
| Hearts Around the World | Served as physician liasion in Dalian, China | 2014 |
| Clinical Events Committee- DEFLECT III Trial. A prospective, randomized, multicenter, non-powered, safety, efficacy, and performance trial will enroll up to 86 evaluable subjects and up to 15 roll-in subjects at up to 15 investigational sites in Europe and Israel. Sponsor: Keystone Heart. Clinical Trials.gov Identifier: NCT02070731. | Served as member of committee to adjudicate clinical events related to a neuro-protective device for TAVRs. | 2014 - 2015 |
| Clinical Events Committee-SALUS. Transcatheter Aortic Valve Replacement System Pivotal trial. Sponsor: Direct Flow. ClinicalTrials.gov Identifier: NCT02163850. | Adjudicated clinical events for a new Transcatheter Aortic valve (Direct Flow) | 2013 - 2016 |
| Clinical Events Committee-DEFLECT I Trial. SMT Embolic DEFLECTion CE Mark Trial. A Study to Evaluate the Safety and Performance of the TriGuard™HDH in Patients Undergoing TAVR. Sponsor: Keystone Heart. Clinical Trials.gov Identifier:. NCT01448421. A prospective, multi-center, single arm feasibility study designed to assess the safety and performance of the SMT device among patients undergoing TAVR procedures. | Adjudicated adverse events in feasibility study of cerebral embolic protection device for patients undergoing TAVR. | 2013 - 2014 |
| Yale New Haven Hospital-YNHH Hospitalist Advisory Committee | Member of YNHH Hospitalist Advisory Committee | 2013 - Present |
| Yale New Haven Hospital-YNHH Medical Directors Leadership Committee | Member of YNHH Medical Directors Leadership Committee | 2013 - Present |
| YNHH-HVC Patient Experience Forum | Co-Chair HVC Paytient Experience Forum | 2013 - Present |
| YNHH-HVC Operations Committee | HVC Operations Council | 2013 - Present |
| Yale University School of Medicine-YSM Cardiology Electives | Served as Director of YSM Student Electives in Section of Cardiovascular Medicine | 2011 - Present |
| YNHH-Therapeutic Hypothermia Committee | Member, Therapeutic Hypothermia Committee-YNHH | 2010 - Present |
| YNHH-Chest Pain Reaccreditation Committee | Member, Chest Pain Center Reaccreditaion Committee | 2010 - Present |
| YNHH-D2B Committee | Member, YNHH D2B Committee | 2008 - Present |
| Hearts Around the World | Served as Physician liasion in St. Petersburg, Russia | 2005 |