2025
Transcatheter vs Surgical Aortic Valve Replacement in Lower-Risk Patients An Updated Meta-Analysis of Randomized Controlled Trials
Reddy R, Howard J, Mack M, Reardon M, Jørgensen T, Hørsted Thyregod H, Toff W, Van Mieghem N, Vora A, Makkar R, Kapadia S, Forrest J, Leon M, Ahmad Y. Transcatheter vs Surgical Aortic Valve Replacement in Lower-Risk Patients An Updated Meta-Analysis of Randomized Controlled Trials. Journal Of The American College Of Cardiology 2025, 85: 926-940. PMID: 40044297, DOI: 10.1016/j.jacc.2024.12.031.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementLower-risk patientsAortic valve replacementPooled survival analysisValve replacementIndividual participant dataPairwise meta-analysesFollow-upMeta-analysis of randomized controlled trialsLonger-term clinical outcomesReduced hazard of deathSevere aortic stenosisFixed effect assumptionsComposite of deathLonger-term follow-upAll-cause deathMean survival time modelsMeta-analysesHazard of deathRate of strokeRandomized controlled trialsSurvival time modelFrailty termProportional odds modelEffect of Sodium-Glucose Cotransporter-2 Inhibitors on the Progression of Aortic Stenosis
Shah T, Zhang Z, Shah H, Fanaroff A, Nathan A, Parise H, Lutz J, Sugeng L, Bellumkonda L, Redfors B, Omerovic E, Petrie M, Vora A, Fiorilli P, Kobayashi T, Ahmad Y, Forrest J, Giri J, Herrmann H, Lansky A. Effect of Sodium-Glucose Cotransporter-2 Inhibitors on the Progression of Aortic Stenosis. JACC Cardiovascular Interventions 2025, 18: 738-748. PMID: 39985508, DOI: 10.1016/j.jcin.2024.11.036.Peer-Reviewed Original ResearchSodium-glucose cotransporter-2 inhibitorsCotransporter-2 inhibitorsAortic stenosisEffects of sodium-glucose cotransporter-2 inhibitorsProgression of aortic stenosisBaseline AS severityAssociated with slower progressionEchocardiographic follow-upRetrospective electronic medical record dataAortic valve sclerosisDisease-related morbidityChronic kidney diseaseSGLT2i usageRates of diabetesSevere ASAS severityEjection fractionFollow-upPrimary outcomeGt;1 yearKidney diseaseMedical record dataYale New Haven Health SystemPatientsObservational studyBeyond Echo-Derived Gradients Balloon-Expandable Valve Outcomes in Small Annuli Patients
Vora A, Forrest J, Krishnaswamy A. Beyond Echo-Derived Gradients Balloon-Expandable Valve Outcomes in Small Annuli Patients. JACC Cardiovascular Interventions 2025, 18: 518-520. PMID: 40010920, DOI: 10.1016/j.jcin.2024.12.007.Peer-Reviewed Original Research
2024
TCT-187 Effect of Sodium-Glucose Cotransporter-2 Inhibitors on the Progression of Aortic Stenosis
Shah T, Shah H, Zhang Z, Fanaroff A, Nathan A, Parise H, Lutz J, Sugeng L, Bellumkonda L, Redfors B, Omerovic E, Petrie M, Vora A, Fiorilli P, Kobayashi T, Ahmad Y, Forrest J, Giri J, Herrmann H, Lansky A. TCT-187 Effect of Sodium-Glucose Cotransporter-2 Inhibitors on the Progression of Aortic Stenosis. Journal Of The American College Of Cardiology 2024, 84: b10. DOI: 10.1016/j.jacc.2024.09.223.Peer-Reviewed Original ResearchTCT-149 Institutional Volume and Failure to Rescue in Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry
Sreenivasan J, Vemulapalli S, Kosinski A, Sherwood M, Cohen D, Forrest J, Ahmad Y, Julien H, Kaneko T, Vora A. TCT-149 Institutional Volume and Failure to Rescue in Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry. Journal Of The American College Of Cardiology 2024, 84: b367. DOI: 10.1016/j.jacc.2024.09.1057.Peer-Reviewed Original Research800.01 Redo-TAVR With the Supra-Annular, Self-Expanding Evolut Platform: Insights from a Multi-Center Real-World Registry
Rogers T, Bapat V, Chetcuti S, Dauerman H, Forrest J, Grubb K, Htun W, Puri R, Reardon M, Tang G, Vora A, Yakubov S, Eisenberg R, Attizzani G. 800.01 Redo-TAVR With the Supra-Annular, Self-Expanding Evolut Platform: Insights from a Multi-Center Real-World Registry. Cardiovascular Revascularization Medicine 2024, 65: 77. DOI: 10.1016/j.carrev.2024.04.173.Peer-Reviewed Original ResearchIn-Hospital Outcomes and 30-Day Readmission Rate After Transcatheter and Surgical Aortic Valve Replacement in Liver Cirrhosis: A Contemporary Propensity-Matched Analysis
Aggarwal A, Jang S, Vardhan S, Webber F, Alam M, Vardhan M, Lancaster G, Ahmad Y, Vora A, Zarich S, Inglessis-Azuaje I, Elmariah S, Forrest J, Davila C. In-Hospital Outcomes and 30-Day Readmission Rate After Transcatheter and Surgical Aortic Valve Replacement in Liver Cirrhosis: A Contemporary Propensity-Matched Analysis. Structural Heart 2024, 8: 100327. PMID: 39670045, PMCID: PMC11632700, DOI: 10.1016/j.shj.2024.100327.Peer-Reviewed Original ResearchSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementTranscatheter aortic valve replacement groupValve replacementIn-hospital mortalityHepatorenal syndromeReadmission ratesCardiogenic shockLiver cirrhosisVascular complicationsIn-hospitalOutcomes of transcatheter aortic valve replacementSurgical risk prediction modelsSurgical aortic valve replacement groupAssociated with significantly lower ratesRates of in-hospital mortalityLimited contemporary dataIn-hospital outcomesSignificantly lower ratesNationwide Readmissions DatabaseCardiac surgeryPeriprocedural morbidityTherapeutic optionsClinical characteristics800.01 Redo-TAVR with the Supra-Annular, Self-Expanding Evolut Platform: Insights from a Multi-Center Real-World Registry
Rogers T, Bapat V, Chetcuti S, Dauerman H, Forrest J, Grubb K, Htun W, Puri R, Reardon M, Tang G, Vora A, Yakubov S, Eisenberg R, Attizzani G. 800.01 Redo-TAVR with the Supra-Annular, Self-Expanding Evolut Platform: Insights from a Multi-Center Real-World Registry. JACC Cardiovascular Interventions 2024, 17: s65. DOI: 10.1016/j.jcin.2024.01.227.Peer-Reviewed Original Research
2023
Progressing Forward in Transcatheter Aortic Valve Replacement for Pure Aortic Regurgitation ∗
Vora A, Sreenivasan J, Forrest J. Progressing Forward in Transcatheter Aortic Valve Replacement for Pure Aortic Regurgitation ∗. JACC Cardiovascular Interventions 2023, 16: 1986-1989. PMID: 37648346, DOI: 10.1016/j.jcin.2023.07.025.Peer-Reviewed Original Research
2022
Site-Level Variation and Predictors of Permanent Pacemaker Implantation Following TAVR in the Evolut Low-Risk Trial
Gada H, Vora AN, Tang GHL, Mumtaz M, Forrest JK, Laham RJ, Yakubov SJ, Deeb GM, Rammohan C, Huang J, Reardon MJ. Site-Level Variation and Predictors of Permanent Pacemaker Implantation Following TAVR in the Evolut Low-Risk Trial. Cardiovascular Revascularization Medicine 2022, 47: 48-54. PMID: 36266154, DOI: 10.1016/j.carrev.2022.10.004.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementPermanent pacemaker implantationNew permanent pacemaker implantationAortic valve replacementPPI rateValve replacementPacemaker implantationClinical outcomesBenefits of TAVRSelf-expanding transcatheter aortic valve replacementBaseline right bundle branch blockRate of PPIEvolut Low Risk trialSurgical aortic valve replacementRight bundle branch blockLow-risk trialsLeft coronary sinusLow-risk patientsBundle branch blockEvolut valvesCoronary sinusGeneral anesthesiaConduction disordersBranch blockProcedural characteristics
2021
TCT-48 Incidence and Outcomes of Atrial Fibrillation in Patients Undergoing TAVR Versus SAVR: Experience From SURTAVI and Low-Risk Randomized Studies
Vora A, Gada H, Sherwood M, Lopes R, Forrest J, Huang J, Reardon M. TCT-48 Incidence and Outcomes of Atrial Fibrillation in Patients Undergoing TAVR Versus SAVR: Experience From SURTAVI and Low-Risk Randomized Studies. Journal Of The American College Of Cardiology 2021, 78: b19. DOI: 10.1016/j.jacc.2021.09.898.Peer-Reviewed Original ResearchOutcomes of Prosthesis-Patient Mismatch Following Supra-Annular Transcatheter Aortic Valve Replacement From the STS/ACC TVT Registry
Tang GHL, Sengupta A, Alexis SL, Bapat VN, Adams DH, Sharma SK, Kini AS, Kodali SK, Ramlawi B, Gada H, Vora AN, Forrest JK, Kaple RK, Liu F, Reardon MJ. Outcomes of Prosthesis-Patient Mismatch Following Supra-Annular Transcatheter Aortic Valve Replacement From the STS/ACC TVT Registry. JACC Cardiovascular Interventions 2021, 14: 964-976. PMID: 33958170, DOI: 10.1016/j.jcin.2021.03.040.Peer-Reviewed Original ResearchConceptsSevere prosthesis-patient mismatchTranscatheter aortic valve replacementProsthesis-patient mismatchDe novo stenosisAortic valve replacementTVT RegistryNovo stenosisValve replacementSTS/ACC TVT RegistryHigh residual gradientPre-procedural factorsLong-term outcomesAortic gradientAortic annulusClinical outcomesSurgical bioprosthesesAdverse outcomesClinical impactPatientsResidual gradientReadmissionRegistryMortalityLinear mixed modelsOutcomes
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply