Featured Publications
Early Outcomes With the Evolut PRO Repositionable Self-Expanding Transcatheter Aortic Valve With Pericardial Wrap
Forrest JK, Mangi AA, Popma JJ, Khabbaz K, Reardon MJ, Kleiman NS, Yakubov SJ, Watson D, Kodali S, George I, Tadros P, Zorn GL, Brown J, Kipperman R, Saul S, Qiao H, Oh JK, Williams MR. Early Outcomes With the Evolut PRO Repositionable Self-Expanding Transcatheter Aortic Valve With Pericardial Wrap. JACC Cardiovascular Interventions 2018, 11: 160-168. PMID: 29348010, DOI: 10.1016/j.jcin.2017.10.014.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisCause of DeathEchocardiographyFemaleHeart Valve ProsthesisHemodynamicsHumansMaleMitral Valve InsufficiencyPericardiumProspective StudiesProsthesis DesignRisk FactorsSeverity of Illness IndexStrokeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsSelf-expanding transcatheter aortic valveSevere symptomatic aortic stenosisEvolut PRO valveSymptomatic aortic stenosisTranscatheter aortic valveAortic stenosisParavalvular leakAortic valveValve Academic Research Consortium-2 criteriaIndependent echocardiographic core laboratoryTranscatheter aortic valve replacementTranscatheter aortic valve systemEchocardiographic core laboratoryPrimary safety endpointPrimary efficacy endpointRemainder of patientsAortic valve replacementProportion of patientsProsthetic valve regurgitationSupra-annular valveEffective orifice areaDisabling strokeCause mortalityEfficacy endpointSafety endpoint
2025
Pathology of Self-Expanding Transcatheter Aortic Bioprostheses and Hypoattenuated Leaflet Thickening
Sato Y, Torii S, Kawai K, Yahagi K, Kutyna M, Kawakami R, Konishi T, Vozenilek A, Jinnouchi H, Sakamoto A, Mori H, Cornelissen A, Mori M, Tanaka T, Sekimoto T, Kutys R, Ghosh S, Forrest J, Reardon M, Romero M, Kolodgie F, Virmani R, Finn A. Pathology of Self-Expanding Transcatheter Aortic Bioprostheses and Hypoattenuated Leaflet Thickening. Circulation Cardiovascular Interventions 2025, 18: e014523. PMID: 39965045, PMCID: PMC11827688, DOI: 10.1161/circinterventions.124.014523.Peer-Reviewed Original ResearchConceptsHypoattenuated leaflet thickeningLeaflet thickeningHistological findingsClinical trialsEvaluate histological findingsAortic valve proceduresSelf-expanding transcatheter aortic valvesAortic bioprosthetic valvesAortic valve leafletsInfective endocarditisValve proceduresTranscatheter aortic valveValve thrombosisAortic bioprosthesesSurgical explantationInflammation scoreAortic valveAcute thrombusImplant durationOrganized thrombusBioprosthetic valvesDay groupLeaflet thrombosisThrombusValve leaflets
2024
Inflow-to-Outflow Stent Frame Expansion, Ellipticity, and Decoupling in Evolut TAVR: Implications for Mid-term Hemodynamic Performance
Puri R, Spencer J, Tchétché D, Van Mieghem N, Forrest J, Reardon M, Sanchez J, Caballero A, Blanke P, Leipsic J, Sorajja P, Deeb G, Fukuhara S, Lucas L, Oyekunle T, Tang G. Inflow-to-Outflow Stent Frame Expansion, Ellipticity, and Decoupling in Evolut TAVR: Implications for Mid-term Hemodynamic Performance. Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 4: 102448. PMID: 40061419, PMCID: PMC11887556, DOI: 10.1016/j.jscai.2024.102448.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementTranscatheter aortic valveFrame deformationHypoattenuated leaflet thickeningEffective orifice areaFrame expansionHemodynamic performanceLeaflet thickeningSelf-expanding transcatheter aortic valve replacementLeaflet regionsOrifice areaDays post-TAVRAortic valve replacementNative aortic annulusInflow geometriesEllipticity ratioVariable ellipticityComputed tomography imagesAortic annulusValve replacementParavalvular regurgitationAnnular levelPost-TAVRAortic valve
2021
Redo‐transcatheter aortic valve replacement with the supra‐annular, self‐expandable Evolut platform: Insights from the Transcatheter valve Therapy Registry
Attizzani GF, Dallan LAP, Forrest JK, Reardon MJ, Szeto WY, Liu F, Pelletier M. Redo‐transcatheter aortic valve replacement with the supra‐annular, self‐expandable Evolut platform: Insights from the Transcatheter valve Therapy Registry. Catheterization And Cardiovascular Interventions 2021, 99: 869-876. PMID: 34533891, DOI: 10.1002/ccd.29941.Peer-Reviewed Original ResearchConceptsTranscatheter Valve Therapy RegistryTranscatheter aortic valveRedo-TAVRTVT RegistryRedo transcatheter aortic valve replacementBetter short-term outcomesTotal aortic regurgitationAortic valve replacementLow-risk patientsShort-term outcomesHospital mortalityIndex hospitalizationAortic regurgitationValve replacementDevice successEvolut RSafety profileMyocardial infarctionAortic valveEvolut PROPatientsRegistryMean gradientOutcomesEvolut
2020
Impact of Repositioning on Outcomes Following Transcatheter Aortic Valve Replacement With a Self-Expandable Valve
Attizzani GF, Dallan LAP, Markowitz A, Yakubov SJ, Deeb GM, Reardon MJ, Forrest JK, Mangi AA, Huang J, Popma JJ. Impact of Repositioning on Outcomes Following Transcatheter Aortic Valve Replacement With a Self-Expandable Valve. JACC Cardiovascular Interventions 2020, 13: 1816-1824. PMID: 32763073, DOI: 10.1016/j.jcin.2020.04.028.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisFemaleHeart Valve ProsthesisHumansMaleMultidetector Computed TomographyProsthesis DesignRandomized Controlled Trials as TopicRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexStrokeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsEvolut RPrimary outcomeValve Academic Research Consortium-2Academic Research Consortium-2Evolut Low Risk trialPrior percutaneous coronary interventionTranscatheter aortic valve replacementEvolut PRO valveLow-risk trialsThoracic Surgeons scoreAortic valve replacementPercutaneous coronary interventionSelf-expandable valvesTranscatheter aortic valveDisabling strokeEvolut valvesSURTAVI trialCause mortalityTrial patientsCoronary interventionSecondary outcomesSurgeons scoreValve replacementClinical outcomesAortic valveThree Generations of Self-Expanding Transcatheter Aortic Valves A Report From the STS/ACC TVT Registry
Forrest JK, Kaple RK, Tang GHL, Yakubov SJ, Nazif TM, Williams MR, Zhang A, Popma JJ, Reardon MJ. Three Generations of Self-Expanding Transcatheter Aortic Valves A Report From the STS/ACC TVT Registry. JACC Cardiovascular Interventions 2020, 13: 170-179. PMID: 31973793, DOI: 10.1016/j.jcin.2019.08.035.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve InsufficiencyAortic Valve StenosisBioprosthesisFemaleHeart Valve ProsthesisHemodynamicsHumansMaleProsthesis DesignRecovery of FunctionRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsEvolut PRO valveTranscatheter aortic valveTVT RegistryAortic regurgitationEvolut RAortic valveSelf-expanding transcatheter aortic valveSTS/ACC TVT RegistryThoracic Surgeons/American CollegeMean aortic valve gradientTranscatheter aortic valve replacement (TAVR) technologyCardiology TVT (Transcatheter Valve Therapy) RegistryTricuspid aortic stenosisAortic valve gradientSignificant aortic regurgitationMild aortic regurgitationSupra-annular valveTranscatheter valve technologyValve gradientHemodynamic statusAortic stenosisAortic annulusEarly outcomesEchocardiographic dataPatient risk
2017
TCT-478 Low Incidence of Paravalvular Leak at 6 Months with the New Self-Expanding Repositionable Transcatheter Aortic Valve with Pericardial Wrap
Forrest J, Williams M. TCT-478 Low Incidence of Paravalvular Leak at 6 Months with the New Self-Expanding Repositionable Transcatheter Aortic Valve with Pericardial Wrap. Journal Of The American College Of Cardiology 2017, 70: b198. DOI: 10.1016/j.jacc.2017.09.592.Peer-Reviewed Original Research
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