1988
Insulin-Mimetic Effects of Vanadate in Primary Cultures of Rat Hepatocytes
Jackson T, Salhanick A, Sparks J, Sparks C, Bolognino M, Amatruda J. Insulin-Mimetic Effects of Vanadate in Primary Cultures of Rat Hepatocytes. Diabetes 1988, 37: 1234-1240. PMID: 3044889, DOI: 10.2337/diab.37.9.1234.Peer-Reviewed Original ResearchConceptsApoB secretionIntracellular lipogenesisHepatic apolipoprotein B secretionPrimary culturesApolipoprotein B secretionTermination of actionEffect of insulinMedium accumulationInsulin-mimetic effectsB secretionEffect of vanadatePostreceptor levelInsulin actionRat hepatocytesInsulinIntracellular glycogen accumulationHepatic proteinsSecretionInsulin-mimetic agentsGlycogen accumulationMimics insulin actionApoB.LipogenesisHepatocytesInhibition
1983
The regulation of lipid synthesis in primary cultures of hepatocytes from nonketotic streptozotocin diabetic rats
Amatruda J, Chang C. The regulation of lipid synthesis in primary cultures of hepatocytes from nonketotic streptozotocin diabetic rats. Metabolism 1983, 32: 224-229. PMID: 6402645, DOI: 10.1016/0026-0495(83)90186-5.Peer-Reviewed Original ResearchConceptsDiabetic ratsDiabetic animalsInsulin responsivenessChronic exposurePrimary culturesAcute effectsBasal lipogenesisStreptozotocin-diabetic ratsStreptozotocin-diabetic animalsLipid synthesisNormal control animalsPresence of insulinInsulin resistanceLipogenic responseInsulin administrationNormal ratsControl animalsNormal controlsNormal animalsRatsFasted ratsInsulinAcute responsivenessLipogenesisM insulin
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