2024
Novel Mechanical Aspiration Thrombectomy in Patients With Acute Pulmonary Embolism: Results From the Prospective APEX-AV Trial
Ranade M, Foster M, Brady P, Sokol S, Butty S, Klein A, Maholic R, Safar A, Patel T, Zlotnick D, Gans D, Pollak J, Ferrera D, Stegman B, Basra S, Moriarty J, Keeling B, Investigators A. Novel Mechanical Aspiration Thrombectomy in Patients With Acute Pulmonary Embolism: Results From the Prospective APEX-AV Trial. Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 4: 102463. PMID: 40061412, PMCID: PMC11887559, DOI: 10.1016/j.jscai.2024.102463.Peer-Reviewed Original ResearchAcute intermediate-risk PEMechanical aspiration thrombectomyIntermediate-risk PEPulmonary embolismAspiration thrombectomyRV/LV ratioClot burdenAdverse eventsMm HgLow rate of adverse eventsMean pulmonary artery pressureEnd pointsRate of adverse eventsAcute pulmonary embolismPulmonary artery pressureSafety end pointDevice-related deathsTreat pulmonary embolismSingle-arm studyEffectiveness end pointAccess site bleedingStatistically significant reductionCardiac injuryClinical deteriorationArterial pressure
2023
Mechanical Thrombectomy for High-Risk Pulmonary Embolism: Insights From the US Cohort of the FLASH Registry
Horowitz J, Jaber W, Stegman B, Rosenberg M, Fanola C, Bhat A, Gondi S, Castle J, Ahmed M, Brown M, Amin R, Bisharat M, Butros P, DuCoffe A, Savin M, Pollak J, Weinberg M, Brancheau D, Toma C, Investigators F. Mechanical Thrombectomy for High-Risk Pulmonary Embolism: Insights From the US Cohort of the FLASH Registry. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 3: 101124. PMID: 39131977, PMCID: PMC11307390, DOI: 10.1016/j.jscai.2023.101124.Peer-Reviewed Original ResearchHigh-risk pulmonary embolismMajor adverse eventsPulmonary embolismMechanical thrombectomyAdverse eventsUS cohortProcedure-related adverse eventsAcute mortalityDepressed cardiac indexDevice-related mortalityRisk pulmonary embolismSubset of patientsSystolic blood pressureFurther prospective dataMin/m2Intensive care unitElevated lactate levelsComers registryFlowTriever SystemMajor bleedingCardiac indexCardiology guidelinesAcute outcomesBlood pressureCare unitHigh-Risk Pulmonary Embolism: Management for the Intensivist
Khosla A, Zhao Y, Mojibian H, Pollak J, Singh I. High-Risk Pulmonary Embolism: Management for the Intensivist. Journal Of Intensive Care Medicine 2023, 38: 1087-1098. PMID: 37455352, DOI: 10.1177/08850666231188290.Peer-Reviewed Original ResearchConceptsHigh-risk pulmonary embolismHigh-risk PE patientsPulmonary embolismRisk stratificationPE patientsTreatment optionsRisk pulmonary embolismMassive pulmonary embolismIntensivist’s perspectiveReperfusion therapySupportive careAcute managementPatientsIntensivistsSupport optionsEmbolismHigh rateCarePhysiological consequencesOutcomesTreatmentOptionsStratificationMorbidityTherapyLonger-Term Outcomes Following Mechanical Thrombectomy for Intermediate- and High-Risk Pulmonary Embolism: 6-Month FLASH Registry Results
Khandhar S, Jaber W, Bunte M, Cho K, Weinberg M, Mina B, Stegman B, Pollak J, Khosla A, Elmasri F, Zlotnick D, Brancheau D, Koenig G, Bisharat M, Li J, Toma C, Investigators F. Longer-Term Outcomes Following Mechanical Thrombectomy for Intermediate- and High-Risk Pulmonary Embolism: 6-Month FLASH Registry Results. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 2: 101000. PMID: 39131661, PMCID: PMC11307656, DOI: 10.1016/j.jscai.2023.101000.Peer-Reviewed Original ResearchChronic thromboembolic pulmonary hypertensionChronic thromboembolic diseaseRisk pulmonary embolismThromboembolic pulmonary hypertensionAcute pulmonary embolismPulmonary embolismFlowTriever SystemCause mortalityPulmonary hypertensionRV functionMechanical thrombectomyThromboembolic diseaseMedical Research Council dyspnea scoreHigh-risk pulmonary embolismTest distanceRapid hemodynamic improvementProportion of patientsRight ventricular functionSix-month outcomesQOL total scoreComers registryDyspnea scoreHemodynamic improvementMulticenter registryExercise capacity
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