2001
Hepatocyte growth factor is a mitogen for olfactory ensheathing cells
Yan H, Nie X, Kocsis J. Hepatocyte growth factor is a mitogen for olfactory ensheathing cells. Journal Of Neuroscience Research 2001, 66: 698-704. PMID: 11746390, PMCID: PMC2605377, DOI: 10.1002/jnr.10009.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodiesBrain Tissue TransplantationCell DivisionCell SizeCell SurvivalCells, CulturedColforsinCulture Media, Serum-FreeCyclic AMPDose-Response Relationship, DrugDrug InteractionsFemaleGlial Fibrillary Acidic ProteinHepatocyte Growth FactorImmunohistochemistryMitogensNeurogliaOlfactory BulbProto-Oncogene Proteins c-metRatsRats, WistarReceptor, Nerve Growth FactorS100 ProteinsTrauma, Nervous SystemConceptsHepatocyte growth factorActivity of HGFAdult rat olfactory bulbHGF/c-Met systemGrowth factorOEC proliferationMitogenic activityOlfactory Ensheathing CellsRat olfactory bulbAbility of HGFC-Met receptorAddition of forskolinCultured OECsOlfactory bulbVariety of cellsDNA synthesisC-MetSerum-free mediumPotential mitogenic activityPotent mitogenMulti-functional effectsImmunocytochemical analysisCell proliferationOlfactory systemOECsTransplantation of an acutely isolated bone marrow fraction repairs demyelinated adult rat spinal cord axons
Sasaki M, Honmou O, Akiyama Y, Uede T, Hashi K, Kocsis J. Transplantation of an acutely isolated bone marrow fraction repairs demyelinated adult rat spinal cord axons. Glia 2001, 35: 26-34. PMID: 11424189, PMCID: PMC2605363, DOI: 10.1002/glia.1067.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornBeta-GalactosidaseBone Marrow TransplantationCells, CulturedEthidiumGlial Fibrillary Acidic ProteinImmunohistochemistryMiceMice, TransgenicMyeloid Progenitor CellsNerve Fibers, MyelinatedNerve RegenerationNeurogliaRatsRats, WistarRecovery of FunctionSpinal CordSpinal Cord InjuriesConceptsBone marrow cellsSpinal cordMyelin-forming cellsMarrow cellsDemyelinated rat spinal cordRat spinal cord axonsDorsal column lesionBone marrow cell fractionRat spinal cordX-irradiation treatmentSpinal cord axonsLacZ transgenic miceSchwann cell myelinationCell fractionCell transplantation techniquesDorsal funiculusPeripheral patternTransgenic miceTransplantation techniquesHematopoietic stem cellsIsolated cell fractionsCordFemoral bonePrecursor cellsTransplantation
1993
Transient presence of GABA in astrocytes of the developing optic nerve
Ochi S, Lim J, Rand M, During M, Sakatani K, Kocsis J. Transient presence of GABA in astrocytes of the developing optic nerve. Glia 1993, 9: 188-198. PMID: 8294149, DOI: 10.1002/glia.440090304.Peer-Reviewed Original ResearchConceptsWhole optic nerveOptic nerveHigh-pressure liquid chromatographyGABA immunoreactivityPostnatal developmentEnzyme glutamic acid decarboxylaseIntact optic nerveRat optic nerveNeonatal optic nerveGlutamic acid decarboxylaseAstrocyte cell bodiesPostnatal day 20GABA immunostainingGFAP stainingPostnatal weekGABA stainingNerveCultured astrocytesAstrocytesDay 20GABAAcid decarboxylaseCell bodiesDevelopmental time courseImmunoreactivity