2025
Novel Elective Course on Substance Use for Pharmacy Students in Jordan
Wazaify M, Al-Khateeb Y, Khoshnood K, Muvvala S, Minahan-Rowley R, Abu-Dahab R, Tetrault J. Novel Elective Course on Substance Use for Pharmacy Students in Jordan. American Journal Of Pharmaceutical Education 2025, 89: 101399. PMID: 40158728, DOI: 10.1016/j.ajpe.2025.101399.Peer-Reviewed Original ResearchConceptsPharmacy studentsHealth professions studentsAverage knowledge scoreSubstance useProfessions studentsBachelor of Pharmacy studentsKnowledge scoresUndergraduate pharmacy studentsDoctor of pharmacyAssess knowledgeElective courseHarm reductionAddiction treatment programsJordanian pharmacistsAddiction medicineFree treatmentSite visitsPositive changesTreatment programsPharmacyLecture-style presentationStudents' attitudesAttitudesPeoplePharmacists
2024
Who feels safe calling 911: are prior experiences of anti-Black racial discrimination associated with hesitancy seeking emergency medical services in the event of accidental drug overdose? – a study protocol
Hall O, Trimble C, Garcia S, Grayson S, Joseph L, Entrup P, Jegede O, Martel J, Tetrault J, Mathis M, Jordan A. Who feels safe calling 911: are prior experiences of anti-Black racial discrimination associated with hesitancy seeking emergency medical services in the event of accidental drug overdose? – a study protocol. Annals Of Medicine 2024, 57: 2439540. PMID: 39697058, PMCID: PMC11660366, DOI: 10.1080/07853890.2024.2439540.Peer-Reviewed Original ResearchConceptsEmergency medical servicesExperiences of racial discriminationCross-sectional surveyMedical servicesAccidental drug overdoseGroup-Based Medical Mistrust ScaleAssociated with health disparitiesDrug overdoseGroup-based medical mistrustMedical Mistrust ScaleEveryday Discrimination ScaleBlack AmericansNon-parametric partial correlationsMedical discriminationRacial discriminationFatal drug overdosesHealth disparitiesQuestionnaire measuring perceptionsRelated health problemsMedical mistrustExploratory factor analysisBlack adultsSociodemographic informationCronbach's alphaGroup-basedImpact of a Web-Based Curriculum on Internal Medicine Resident Use of Stigmatizing Language for Substance Use Disorder
Samberg D, Spinella S, Rothenberger S, Tetrault J, Childers J. Impact of a Web-Based Curriculum on Internal Medicine Resident Use of Stigmatizing Language for Substance Use Disorder. Substance Abuse 2024, 46: 313-319. PMID: 39690470, DOI: 10.1177/29767342241298057.Peer-Reviewed Original ResearchConceptsInternal medicine residentsSubstance use disordersPre-curriculumMedicine residentsPost-curriculumClinical terminologyStigma associated with substance use disorderNon-stigmatizing languagePost-curriculum surveysNational medical organizationsUse disorderWeb-based curriculumStigma levelsStigmatizing terminologyImproved documentationPatient careOpioid use disorderConsiderable stigmaVideo encountersInteractive curriculumWell-receivedSimulated patientsStigmatizing languageResidents' useCase write-ups
2023
Epidemiology of substance use and mental health disorders among forced migrants displaced from the MENAT region: A systematic review and meta-analysis protocol
Kazemitabar M, Nyhan K, Makableh N, Minahan-Rowley R, Ali M, Wazaify M, Tetrault J, Khoshnood K. Epidemiology of substance use and mental health disorders among forced migrants displaced from the MENAT region: A systematic review and meta-analysis protocol. PLOS ONE 2023, 18: e0292535. PMID: 37797050, PMCID: PMC10553213, DOI: 10.1371/journal.pone.0292535.Peer-Reviewed Original ResearchConceptsMental health disordersSubstance use disordersSystematic reviewRegistration IDHealth disordersJoanna Briggs Institute checklistBias 2 toolRisk of biasInternational Prospective RegisterDatabases of EmbaseMeta-analysis protocolJoanna Briggs InstituteComprehensive systematic reviewRandom-effects modelSystematic review protocolCochrane riskMEDLINE search strategySubgroup analysisProspective RegisterRisk factorsObservational studyUse disordersHealth providersIntervention studiesYears of life lost due to deaths of despair and COVID-19 in the United States in 2020: patterns of excess mortality by gender, race and ethnicity
Entrup P, Brodsky L, Trimble C, Garcia S, Mohamed N, Deaner M, Martell J, Teater J, Jordan A, Tetrault J, Hall O. Years of life lost due to deaths of despair and COVID-19 in the United States in 2020: patterns of excess mortality by gender, race and ethnicity. International Journal For Equity In Health 2023, 22: 161. PMID: 37612748, PMCID: PMC10464324, DOI: 10.1186/s12939-023-01949-9.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol-Related DisordersAmerican Indian or Alaska NativeAsianBlack or African AmericanCause of DeathCost of IllnessCOVID-19Cross-Sectional StudiesDrug OverdoseEthanolEthnicityFemaleHealth InequitiesHispanic or LatinoHumansLife ExpectancyMaleMortality, PrematureNative Hawaiian or Pacific IslanderRace FactorsSex FactorsSocial Determinants of HealthSuicideUnited StatesWhiteConceptsYears of lifeDeaths of despairCOVID-19Mental health workforce developmentCross-sectional studyICD-10 codesCause of deathCOVID-19 mortalityCDC WONDER databaseSubstance use treatmentHealth workforce developmentLatino personsExcess mortalityMortality burdenMore deathsDeath recordsHigh mortalityBehavioral health researchSocial determinantsGreater burdenYLLUse treatmentConclusionsThis studyPandemic onsetMortalityImproving HIV and HCV Testing in Substance Use Disorder Programs (SUDs) That Provide Medications for Opiate Use Disorder (MOUD): Role of Addressing Barriers and Implementing Universal and Site-Specific Approaches
Brooks R, Wegener M, Freeman B, Fowles C, Madden L, Tetrault J, Nichols L, Altice F, Villanueva M. Improving HIV and HCV Testing in Substance Use Disorder Programs (SUDs) That Provide Medications for Opiate Use Disorder (MOUD): Role of Addressing Barriers and Implementing Universal and Site-Specific Approaches. Health Promotion Practice 2023, 24: 1018-1028. PMID: 37439759, DOI: 10.1177/15248399231169791.Peer-Reviewed Original ResearchConceptsHIV/HCV coinfectionSubstance use disorder programsHCV testingOpiate use disorderHCV coinfectionUse disordersNominal group techniqueSubstance use disorder treatment centersCascade of careRates of HIVDisorder treatment centersQuality improvement effortsRate of testingHCV acquisitionHCV cureImproving HIVSUD clinicsHepatitis CHIV testingPrior diagnosisSubsequent referralReferral ratesHIV epidemicHIVTreatment centers
2022
Association Between Alcohol Use Disorder and Receipt of Direct-Acting Antiviral Hepatitis C Virus Treatment
Haque L, Fiellin D, Tate J, Esserman D, Bhattacharya D, Butt A, Crystal S, Edelman E, Gordon A, Lim J, Tetrault J, Williams E, Bryant K, Cartwright E, Rentsch C, Justice A, Re V, McGinnis K. Association Between Alcohol Use Disorder and Receipt of Direct-Acting Antiviral Hepatitis C Virus Treatment. JAMA Network Open 2022, 5: e2246604. PMID: 36515952, PMCID: PMC9856353, DOI: 10.1001/jamanetworkopen.2022.46604.Peer-Reviewed Original ResearchConceptsCurrent alcohol use disorderLow-risk drinkingAlcohol use disorderVeterans Health AdministrationHistory of AUDDAA treatmentAlcohol use categoriesAUD historyCohort studyRisk drinkingUse disordersDirect acting antiviral (DAA) treatmentAlcohol Use Disorders Identification Test-Consumption (AUDIT-C) questionnaireHepatitis C virus infectionHepatitis C virus (HCV) treatmentCox proportional hazards regressionC virus infectionC virus treatmentProportional hazards regressionTenth Revision diagnosisAUDIT-C questionnaireInternational Statistical ClassificationRelated Health ProblemsAntiviral treatmentRevision diagnosisThe impact of benzodiazepine exposure on treatment retention in an open-access methadone program: A retrospective cohort study
Morford K, Tetrault J, Zhou B, Li F, Gleeson B, Edelman E, Stein M, Barry D, Madden L. The impact of benzodiazepine exposure on treatment retention in an open-access methadone program: A retrospective cohort study. Drug And Alcohol Dependence 2022, 241: 109707. PMID: 36423462, PMCID: PMC9777057, DOI: 10.1016/j.drugalcdep.2022.109707.Peer-Reviewed Original ResearchConceptsBenzodiazepine exposureRetrospective cohort studyKaplan-Meier analysisTreatment retentionCohort studyCox regressionTreatment durationMedian treatment durationMultivariable Cox regressionCohort of patientsOpioid treatment programsOpioid use disorderLog-rank testSame-day accessDrug Administration recommendationsTreatment discontinuationUrine toxicologyMeier analysisMethadone programsUse disordersPatientsAdministration recommendationsTreatment entryTreatment programTreatment barriersGrief at the Heart of the Opioid Overdose Crisis: Past Lessons and Present Implications
Morford KL, Batchelor HM, Tetrault JM. Grief at the Heart of the Opioid Overdose Crisis: Past Lessons and Present Implications. Journal Of Addiction Medicine 2022, 16: 613-615. PMID: 35165230, DOI: 10.1097/adm.0000000000000976.Peer-Reviewed Original ResearchConceptsOpioid use disorderOpioid overdose crisisOverdose crisisImmunodeficiency syndrome (AIDS) epidemicCare of peopleTreatment outcomesOverdose deathsUse disordersEmotional burdenSocial support networksContext of stigmaHarmful consequencesSupport networksRole of griefGriefPatientsOverdoseCliniciansIntegration of medication for opioid use disorder training into graduate nursing education
Barcelona V, Wischik DL, Marshall A, Tetrault JM. Integration of medication for opioid use disorder training into graduate nursing education. Nursing Forum 2022, 57: 869-873. PMID: 35616353, DOI: 10.1111/nuf.12753.Peer-Reviewed Original ResearchConceptsOpioid use disorderDrug Enforcement AdministrationIntegration of medicationPrescription of medicationsGeneral medical settingsHealth care providersMore health care providersOpioid overdose crisisGraduate nursing curriculumNurse practitioner studentsRelated complicationsMedicine cliniciansCare providersX-waiverUse disordersDisorder trainingInterprofessional partnershipsNursing educationOverdose crisisPractitioner studentsAdvanced practiceMedical settingsMedicationsCOVID-19 pandemicNP studentsPrimary Care Associated With Follow Up Viral Load Testing in Patients Cured of Hepatitis C Infection With Direct Acting Antivirals at a Multidisciplinary Addiction Treatment Program: Insights From a Real-World Setting
Haque LY, Butner JL, Shi JM, Henry S, Deng Y, Ciarleglio MM, Madden LM, Tetrault JM. Primary Care Associated With Follow Up Viral Load Testing in Patients Cured of Hepatitis C Infection With Direct Acting Antivirals at a Multidisciplinary Addiction Treatment Program: Insights From a Real-World Setting. Journal Of Addiction Medicine 2022, 16: 333-339. PMID: 34483278, PMCID: PMC9033626, DOI: 10.1097/adm.0000000000000910.Peer-Reviewed Original ResearchConceptsHepatitis C virus infectionUrine toxicology resultsDirect acting antiviralsViral load testingSubstance use disordersAddiction treatment programsHCV reinfectionActing antiviralsToxicology resultsUse disordersDirect acting antiviral therapyTreatment programReal-world clinical settingHCV reinfection ratesActing antiviral (DAA) therapyC virus infectionHepatitis C infectionMedical service useCohort of patientsPrimary medical careSubstance use statusAddiction treatment settingsQuality improvement initiativesHCV cureC infectionCommentary Article: Strategic Planning for Addiction Programs within Academic Medical Centers: Examples from the Yale Program in Addiction Medicine
Biegacki ET, Tetrault JM, Fiellin DA. Commentary Article: Strategic Planning for Addiction Programs within Academic Medical Centers: Examples from the Yale Program in Addiction Medicine. Substance Abuse 2022, 43: 1215-1220. PMID: 35657646, DOI: 10.1080/08897077.2022.2074606.Commentaries, Editorials and Letters
2021
Low Dose Initiation of Buprenorphine: A Narrative Review and Practical Approach
Cohen SM, Weimer MB, Levander XA, Peckham AM, Tetrault JM, Morford KL. Low Dose Initiation of Buprenorphine: A Narrative Review and Practical Approach. Journal Of Addiction Medicine 2021, 16: 399-406. PMID: 34954746, DOI: 10.1097/adm.0000000000000945.Peer-Reviewed Original ResearchConceptsLow dose initiationFull opioid agonistsDose initiationOpioid withdrawal symptomsOpioid agonistsBuprenorphine doseWithdrawal symptomsHigh potency synthetic opioidsOpioid use disorderAppropriate clinical situationsMu-opioid receptorsBuprenorphine initiationOpioid withdrawalStarting doseOutpatient settingCare coordinationDose changesOverdose deathsCurrent evidenceUse disordersBuprenorphineTherapeutic levelsClinical situationsSynthetic opioidsNarrative reviewPrimary care and medication management characteristics among patients receiving office-based opioid treatment with buprenorphine
Du CX, Shi J, Tetrault JM, Madden LM, Barry DT. Primary care and medication management characteristics among patients receiving office-based opioid treatment with buprenorphine. Family Practice 2021, 39: 234-240. PMID: 34893825, PMCID: PMC8947790, DOI: 10.1093/fampra/cmab166.Peer-Reviewed Original ResearchConceptsOffice-based opioid treatmentPrimary care providersOpioid use disorderUrine toxicologyOpioid treatmentMore primary care providersOutpatient primary care clinicsChronic pain statusChronic viral hepatitisPrimary care clinicsCommon comorbid conditionsPrimary care characteristicsAddiction treatment settingsHigher median numberEvidence-based treatment modelsOBOT patientsOBOT programOlder patientsPain statusViral hepatitisCommon medicationsRetrospective reviewCare clinicsChronic painComorbid conditionsSOAPs and SUDs: Patients With Substance Use Disorders and What Clinicians Should Know About the Cures Act
Chan CA, Tetrault JM, Fiellin DA, Weimer MB. SOAPs and SUDs: Patients With Substance Use Disorders and What Clinicians Should Know About the Cures Act. Journal Of Addiction Medicine 2021, 16: 141-142. PMID: 34049315, DOI: 10.1097/adm.0000000000000879.Commentaries, Editorials and LettersAddiction Screening—The A Star Is Born Movie Series and Destigmatization of Substance Use Disorders
Oldfield BJ, Tetrault JM, Berland G. Addiction Screening—The A Star Is Born Movie Series and Destigmatization of Substance Use Disorders. JAMA 2021, 325: 915-917. PMID: 33687448, DOI: 10.1001/jama.2020.25256.Peer-Reviewed Original ResearchShould You Recommend Cannabinoids for This Patient With Painful Neuropathy? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
Smetana GW, Tetrault JM, Hill KP, Burns RB. Should You Recommend Cannabinoids for This Patient With Painful Neuropathy? : Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Annals Of Internal Medicine 2021, 174: 237-246. PMID: 33556279, DOI: 10.7326/m20-7945.Peer-Reviewed Original ResearchConceptsNeuropathic painChronic painBeth Israel Deaconess Medical CenterPlacebo-treated patientsChronic neuropathic painPainful diabetic neuropathyPotential therapeutic effectsPrimary care practicesEvidence Review GroupEffects of cannabisNoncancer painPainful neuropathyDiabetic neuropathyTherapeutic effectMedical CenterGeneral internistsPainMedical cannabisReview GroupPatientsCare practicesSystematic reviewAddiction medicineCBD productsPatient interestAssociation entre l’usage de cannabis et les principales anomalies congénitales.
Bisio C, Tetrault J. Association entre l’usage de cannabis et les principales anomalies congénitales. Revue Médicale Suisse 2021, 17: 1334. PMID: 34264039, DOI: 10.53738/revmed.2021.17.745.1334.Peer-Reviewed Original Research
2020
Stitching A Solution to the Addiction Epidemic: A Longitudinal Addiction Curricular Thread across Four Years of Medical Training
Muvvala SB, Schwartz ML, Petrakis I, O'Connor P, Tetrault JM. Stitching A Solution to the Addiction Epidemic: A Longitudinal Addiction Curricular Thread across Four Years of Medical Training. Substance Abuse 2020, 41: 475-479. PMID: 31951809, DOI: 10.1080/08897077.2019.1709606.Peer-Reviewed Original ResearchConceptsCurricular threadPractice-based learning activitiesMedical school curriculumComprehensive needs assessmentCurriculum goalsLearning activitiesSchool curriculumCurriculum developmentClerkship directorsDidactic activitiesEducational strategiesMedical schoolsKern modelClinical simulationMedical trainingCurriculumWorkshop exercisesNeeds assessmentWork forceClinical experienceSchoolsEducationPublic health impactImplementationInstitutionsSubstance Use Disorders in Recently Hospitalized Patients With Cirrhosis.
Haque LY, Jakab S, Deng Y, Ciarleglio MM, Tetrault JM. Substance Use Disorders in Recently Hospitalized Patients With Cirrhosis. Journal Of Addiction Medicine 2020, 14: e337-e343. PMID: 32530887, PMCID: PMC9033633, DOI: 10.1097/adm.0000000000000677.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersAddiction treatmentAlcohol-related liver diseaseImpact of SUDHepatitis C infectionMedical record reviewMinority of patientsNumber of hospitalizationsRoutine clinical careAlcohol use disorderHepatology clinicC infectionCause mortalityConsecutive patientsMedian ageCommon etiologyLiver diseaseRecord reviewSignificant morbidityRetrospective studySUD careCirrhosisClinical careHospitalization
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