2017
Metformin Prevents the Progression of Dysplastic Mucosa of the Head and Neck to Carcinoma in Nondiabetic Patients
Lerner MZ, Mor N, Paek H, Blitzer A, Strome M. Metformin Prevents the Progression of Dysplastic Mucosa of the Head and Neck to Carcinoma in Nondiabetic Patients. Annals Of Otology Rhinology & Laryngology 2017, 126: 340-343. PMID: 28103701, DOI: 10.1177/0003489416688478.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaAdjuvant metformin therapyHNC patientsMetformin therapyDiabetes mellitusOral cavity squamous cell carcinomaType 2 diabetes mellitusLaryngeal squamous cell carcinomaOral anti-hyperglycemic agentAbnormal glucose metabolismRisk of malignancyAnti-hyperglycemic agentsMultifocal dysplastic lesionsNondiabetic patientsAdjuvant therapyNondiabetic populationOverall survivalAdditional surgeryMucosal lesionsCase seriesOral lesionsCell carcinomaNeck cancerDysplastic lesionsDysplastic mucosa
2012
Comparison of the Effect on Long-Term Outcomes in Patients With Thoracic Aortic Aneurysms of Taking Versus Not Taking a Statin Drug
Jovin IS, Duggal M, Ebisu K, Paek H, Oprea AD, Tranquilli M, Rizzo J, Memet R, Feldman M, Dziura J, Brandt CA, Elefteriades JA. Comparison of the Effect on Long-Term Outcomes in Patients With Thoracic Aortic Aneurysms of Taking Versus Not Taking a Statin Drug. The American Journal Of Cardiology 2012, 109: 1050-1054. PMID: 22221941, DOI: 10.1016/j.amjcard.2011.11.038.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmLong-term outcomesComposite end pointAortic aneurysmAneurysm repairEnd pointImproved long-term outcomesOutcomes of patientsCohort of patientsKaplan-Meier analysisMedian followStatin intakeStatin therapyMedical therapyStatinsFirst presentationPatientsSurvival rateAneurysmsStatin drugsOutcomesTherapyIntakeRepairCohort