2024
Mental-somatic multimorbidity in trajectories of cognitive function for middle-aged and older adults
Chen S, Nagel C, Liu R, Botoseneanu A, Allore H, Newsom J, Thielke S, Kaye J, Quiñones A. Mental-somatic multimorbidity in trajectories of cognitive function for middle-aged and older adults. PLOS ONE 2024, 19: e0303599. PMID: 38743678, PMCID: PMC11093294, DOI: 10.1371/journal.pone.0303599.Peer-Reviewed Original ResearchConceptsOdds of cognitive impairmentGroup-based trajectory modelingMultimorbidity combinationsLate-life increaseOlder adultsNon-Hispanic white adultsHigh riskHealth and Retirement StudyMiddle-agedHealth-related factorsTrajectories of cognitive functionCognitive declineCognitive impairmentMultinomial logistic regression modelMultinomial logistic regression analysisLow riskLogistic regression modelsLow initial riskTrajectory group membershipLogistic regression analysisRetirement StudyNon-HispanicMultimorbidityWhite adultsHispanic respondents
2023
RACIAL/ETHNIC AND MULTIMORBIDITY DIFFERENCES IN DEMENTIA ONSET AMONG MIDDLE-AGED AND OLDER ADULTS
Chen S, Nagel C, Botoseneanu A, Allore H, Newsom J, Thielke S, Kaye J, Quiñones A. RACIAL/ETHNIC AND MULTIMORBIDITY DIFFERENCES IN DEMENTIA ONSET AMONG MIDDLE-AGED AND OLDER ADULTS. Innovation In Aging 2023, 7: 747-747. PMCID: PMC10737488, DOI: 10.1093/geroni/igad104.2416.Peer-Reviewed Original ResearchDementia onsetRace/ethnicityHigh riskOlder adultsModifiable risk factorsNon-Hispanic blacksCovariate-adjusted modelsContext of multimorbidityNon-Hispanic white respondentsNon-Hispanic White older adultsWhite older adultsRacial/EthnicMultimorbidity combinationsRisk factorsDiscrete-time survival modelsHigh prevalenceHigher oddsMultimorbidityWhite adultsDementiaMiddle AgedLater lifeAdultsSignificant differencesRiskCARE-RECEIVING CHARACTERISTICS AMONG OLDER ADULTS WITH DIFFERENT MENTAL–SOMATIC MULTIMORBIDITY COMBINATIONS
Liu M, Nagel C, Chen S, Allore H, Kaye J, Quiñones A. CARE-RECEIVING CHARACTERISTICS AMONG OLDER ADULTS WITH DIFFERENT MENTAL–SOMATIC MULTIMORBIDITY COMBINATIONS. Innovation In Aging 2023, 7: 821-821. PMCID: PMC10738666, DOI: 10.1093/geroni/igad104.2648.Peer-Reviewed Original ResearchCognitive impairmentCognitive impairment groupMultimorbidity combinationsOlder adultsDepression groupMore caregiversImpairment groupLower self-rated healthSomatic conditionsNon-Hispanic blacksCombination of depressionSelf-rated healthMore functional limitationsAging Trends StudyMore hoursMultimorbidity patternsUnderweight BMINational HealthFunctional limitationsMedicaid recipientsHealth outcomesDifferent careMental healthImpairmentDepressionLATENT CLASSES OF MULTIMORBIDITY AND ASSOCIATED CARE-RECEIVING CHARACTERISTICS FOR US OLDER ADULTS
Liu M, Nagel C, Chen S, Kaye J, Allore H, Quiñones A. LATENT CLASSES OF MULTIMORBIDITY AND ASSOCIATED CARE-RECEIVING CHARACTERISTICS FOR US OLDER ADULTS. Innovation In Aging 2023, 7: 823-823. PMCID: PMC10739216, DOI: 10.1093/geroni/igad104.2654.Peer-Reviewed Original ResearchOlder adultsCare needsMore unmet needsDifferent care needsType of careAging Trends StudyMultimorbidity combinationsMultimorbidity patternsMusculoskeletal conditionsChronic conditionsNational HealthMedian numberUnmet needAssociated careMultimorbidityCareIADL domainsLatent classesAbstract Older adultsAdultsFurther investigationFour-class solutionHealthy classCaregiversSmall proportion
2022
MENTAL-SOMATIC MULTIMORBIDITY IN GROUP-BASED TRAJECTORIES OF COGNITIVE FUNCTION FOR MIDDLE-AGED AND OLDER ADULTS
Chen S, Nagel C, Botoseneanu A, Allore H, Newsom J, Thielke S, Kaye J, Quiñones A. MENTAL-SOMATIC MULTIMORBIDITY IN GROUP-BASED TRAJECTORIES OF COGNITIVE FUNCTION FOR MIDDLE-AGED AND OLDER ADULTS. Innovation In Aging 2022, 6: 610-610. PMCID: PMC9770737, DOI: 10.1093/geroni/igac059.2273.Peer-Reviewed Original ResearchLow baseline riskMultimorbidity combinationsBaseline riskCognitive impairmentSomatic multimorbidityHigher oddsHigher baseline riskCognitive impairment riskCognitive performanceGroup-based trajectory modelingRisk modificationSubsequent riskMultimorbiditySociodemographic factorsMental multimorbidityCognitive declineCognitive functionMiddle AgedOlder adultsImpairment riskImpairmentTrajectory class membershipRiskStrokeRetirement Study
2021
Racial and Ethnic Differences in Multimorbidity Changes Over Time
Quiñones AR, Newsom JT, Elman MR, Markwardt S, Nagel CL, Dorr DA, Allore HG, Botoseneanu A. Racial and Ethnic Differences in Multimorbidity Changes Over Time. Medical Care 2021, 59: 402-409. PMID: 33821829, PMCID: PMC8024615, DOI: 10.1097/mlr.0000000000001527.Peer-Reviewed Original ResearchConceptsMinimal diseaseOlder adultsProspective cohort studyHigher depressive symptomsMultimorbidity combinationsEthnic older adultsCohort studyMultimorbidity patternsLung diseaseHeart diseaseRetirement Study respondentsDelay progressionDepressive symptomsMultimorbidityDiseaseLatent class analysisLatent classesEthnic differencesWhite AmericansStudy respondentsMultinomial logistic modelAdultsClass analysisLogistic modelParticipants
2020
An Agenda for Addressing Multimorbidity and Racial and Ethnic Disparities in Alzheimer’s Disease and Related Dementia
Quiñones AR, Kaye J, Allore HG, Botoseneanu A, Thielke SM. An Agenda for Addressing Multimorbidity and Racial and Ethnic Disparities in Alzheimer’s Disease and Related Dementia. American Journal Of Alzheimer's Disease & Other Dementias® 2020, 35: 1533317520960874. PMID: 32969234, PMCID: PMC7984095, DOI: 10.1177/1533317520960874.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseEthnic disparitiesMultiple chronic diseasesMultimorbidity combinationsPoor outcomeAdverse outcomesChronic diseasesHigh burdenRelated dementiaClinical treatmentDiseaseADRDU.S. populationDementia researchMultimorbidityOutcomesBurdenRiskBroad effectsPopulationDementiaDisparitiesCareCaregivers