2023
Brief Report: Changing Characteristics Among In-Hospital HIV Deaths: An 11-Year Retrospective Review of a Regional Hospital in South Africa
Lombardo A, Materi J, Caturegli G, Milovanovic M, Martinson N, Calver A, Nonyane B, Golub J, Hoffmann C, Variava E. Brief Report: Changing Characteristics Among In-Hospital HIV Deaths: An 11-Year Retrospective Review of a Regional Hospital in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 94: 185-189. PMID: 37757855, DOI: 10.1097/qai.0000000000003249.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyExpansion of antiretroviral therapyHIV-positiveProportion of decedentsBurden of HIVAge groupsProportion of HIV patientsAge of decedentsHIV-associated mortalityProportion of HIV-positiveYounger age groupsOlder age groupsHealth facilitiesDecedent characteristicsLog-binomialAIDS-defining illnessRegional hospitalHIV deathsHIV statusAdvanced HIV diseaseRecord dataMultinomial regressionOlder individualsOpportunistic illnessesProportion of patientsTrends on Near-Infrared Spectroscopy Associated With Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation
Zhao D, Shou B, Caturegli G, Whitman G, Kim B, Cho S, Investigators O. Trends on Near-Infrared Spectroscopy Associated With Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation. ASAIO Journal 2023, 69: 1083-1089. PMID: 37556554, PMCID: PMC10843160, DOI: 10.1097/mat.0000000000002032.Peer-Reviewed Original ResearchConceptsCerebral near-infrared spectroscopyArea under the curveVenoarterial extracorporeal membrane oxygenationAcute brain injuryVA-ECMO patientsExtracorporeal membrane oxygenationVA-ECMOMembrane oxygenationCerebral regional oxygen saturationHypoxic ischemic brain injuryAssociated with acute brain injuryRegional oxygen saturationBrain injuryIschemic brain injuryECMO cannulationCerebral desaturationIntracranial hemorrhageConsecutive hoursNIRS monitoringOxygen saturationECMOIncreased oddsIschemic strokePatientsRSO 2Challenges in determining death by neurologic criteria in extracorporeal membrane oxygenation – A single center experience
Zhao D, Caturegli G, Wilcox C, Stephens R, Kim B, Keller S, Geocadin R, Suarez J, Whitman G, Cho S. Challenges in determining death by neurologic criteria in extracorporeal membrane oxygenation – A single center experience. Perfusion 2023, 39: 1238-1246. PMID: 37387124, PMCID: PMC10756925, DOI: 10.1177/02676591231187548.Peer-Reviewed Original ResearchConceptsExtracorporeal membrane oxygenation patientsExtracorporeal membrane oxygenationApnea testingWithdrawal of life-sustaining treatmentAncillary testsMembrane oxygenationSingle center experienceVV ECMO patientsTertiary care centerAbsent brainstem reflexesNeurological exam findingsLife-sustaining treatmentVV-ECMORetrospective reviewTertiary centerImaging findingsExam findingsBrainstem reflexesCenter's experienceNeurological examPatientsDiagnostic criteriaCare centerDetermination of DNCNeurologic criteria
2022
Early Low Pulse Pressure in VA-ECMO Is Associated with Acute Brain Injury
Shou B, Wilcox C, Florissi I, Kalra A, Caturegli G, Zhang L, Bush E, Kim B, Keller S, Whitman G, Cho S. Early Low Pulse Pressure in VA-ECMO Is Associated with Acute Brain Injury. Neurocritical Care 2022, 38: 612-621. PMID: 36167950, PMCID: PMC10040467, DOI: 10.1007/s12028-022-01607-y.Peer-Reviewed Original ResearchConceptsAssociated with acute brain injuryAcute brain injuryLower pulse pressureHypoxic ischemic brain injuryVA-ECMOIschemic brain injuryPulse pressureIntracranial hemorrhageCerebral edemaVenoarterial extracorporeal membrane oxygenationECMO day 1VA-ECMO patientsIschemic strokeExtracorporeal membrane oxygenationRetrospective analysis of adultsBrain injuryMarkers of cardiovascular functionTertiary care centerPulse pressure <Multivariate logistic regressionBrain deathContinuous-flow mechanical circulatory supportMechanical circulatory supportAnalysis of adultsECMO support
2021
The Impact of Surgical Delays on Short- and Long-Term Survival Among Colon Cancer Patients
Lo B, Caturegli G, Stem M, Biju K, Safar B, Efron J, Rajput A, Atallah C. The Impact of Surgical Delays on Short- and Long-Term Survival Among Colon Cancer Patients. The American Surgeon 2021, 87: 1783-1792. PMID: 34666557, DOI: 10.1177/00031348211047511.Peer-Reviewed Original ResearchConceptsColon cancer patientsImpact of surgical delayOverall survivalIII colon cancerLong-term survivalSurgical delayCancer patientsSurgery 3Associated with worse 5-year overall survivalColon cancerDisease stageStage IStage III colon cancerNational Cancer DatabaseDiagnosis to surgeryPathological disease stageII diseaseCancer DatabaseGt;12 weeksAdult patientsSubgroup analysisColon cancer diagnosisSurgeryPatientsWaiting timeStress-Induced (Takotsubo) Cardiomyopathy After Liver Transplant Rescued with Venoarterial Extracorporeal Membrane Oxygenation
Caturegli G, Crane M, Etchill E, Giuliano K, Nguyen M, Philosophe B, Cho S, Wittstein I, Whitman G. Stress-Induced (Takotsubo) Cardiomyopathy After Liver Transplant Rescued with Venoarterial Extracorporeal Membrane Oxygenation. ASAIO Journal 2021, 68: e66-e68. PMID: 35349528, DOI: 10.1097/mat.0000000000001453.Peer-Reviewed Original ResearchConceptsVenoarterial extracorporeal membrane oxygenationExtracorporeal membrane oxygenationLiver transplantationVA-ECMOTakotsubo syndromeMembrane oxygenationRefractory to high-doseYear old male patientRecovery of cardiac functionDeceased donor liver transplantationStress-induced cardiomyopathyOld male patientDonor liver transplantationHigh-doseMale patientsMedical therapyCardiac functionHepatic graftMyocardial recoveryPatientsCardiovascular diseaseTransplantationCardiomyopathyLiverTakotsuboDuration of Hyperoxia and Neurologic Outcomes in Patients Undergoing Extracorporeal Membrane Oxygenation
Al-Kawaz M, Canner J, Caturegli G, Kannapadi N, Balucani C, Shelley L, Kim B, Choi C, Geocadin R, Whitman G, Cho S. Duration of Hyperoxia and Neurologic Outcomes in Patients Undergoing Extracorporeal Membrane Oxygenation. Critical Care Medicine 2021, 49: e968-e977. PMID: 33935164, DOI: 10.1097/ccm.0000000000005069.Peer-Reviewed Original ResearchConceptsVenoarterial extracorporeal membrane oxygenationExtracorporeal membrane oxygenationPoor neurological outcomeNeurological outcomeMembrane oxygenationDuration of hyperoxiaSevere hyperoxiaExtracorporeal membrane oxygenation patientsAssociated with poor neurological outcomeVenoarterial extracorporeal membrane oxygenation patientsMultivariate logistic regression analysisArea under the curveModified Rankin ScaleAssociated with inhospital mortalityLogistic regression analysisJohns Hopkins HospitalOxygenation patientsRetrospective analysisInhospital mortalityMultivariate analysisPrimary outcomeRankin ScaleNeurological functionPatientsPaO2 valuesManagement of syringomyelia associated with tuberculous meningitis: A case report and systematic review of the literature
Kannapadi N, Alomari S, Caturegli G, Bydon A, Cho S. Management of syringomyelia associated with tuberculous meningitis: A case report and systematic review of the literature. Journal Of Clinical Neuroscience 2021, 87: 20-25. PMID: 33863527, DOI: 10.1016/j.jocn.2021.01.052.Peer-Reviewed Original ResearchConceptsSurgical interventionDeterminants of tuberculosisSurgically managed patientsCase-control studyTB meningitisMedian ageTB presentationMedian timeClinical characteristicsCase reportSyringomyelia casesTB onsetPost-treatment outcomesSystematic reviewTB infectionInclusion criteriaManaging patientsSyringomyeliaNo treatmentPatientsPrior symptomsInterventionOutcomesSample sizeTuberculosis
2020
Risk Factors of Ischemic and Hemorrhagic Strokes During Venovenous Extracorporeal Membrane Oxygenation: Analysis of Data From the Extracorporeal Life Support Organization Registry.
Cho S, Canner J, Caturegli G, Choi C, Etchill E, Giuliano K, Chiarini G, Calligy K, Rycus P, Lorusso R, Kim B, Sussman M, Suarez J, Geocadin R, Bush E, Ziai W, Whitman G. Risk Factors of Ischemic and Hemorrhagic Strokes During Venovenous Extracorporeal Membrane Oxygenation: Analysis of Data From the Extracorporeal Life Support Organization Registry. Critical Care Medicine 2020, 49: 91-101. PMID: 33148951, PMCID: PMC9513801, DOI: 10.1097/ccm.0000000000004707.Peer-Reviewed Original ResearchConceptsHemorrhagic strokeRisk factorsVenovenous extracorporeal membrane oxygenationExtracorporeal membrane oxygenationExtracorporeal Life Support Organization registryExtracorporeal membrane oxygenation patientsAcute brain injuryAssociated with hemorrhagic strokeVenovenous extracorporeal membrane oxygenation patientsIschemic strokeAssociated with ischemic strokeBrain injuryMembrane oxygenationGastrointestinal hemorrhageOxygenation patientsVenovenous extracorporeal membrane oxygenation supportExtracorporeal membrane oxygenation supportInhospital mortalityExtracorporeal membrane oxygenation centersExtracorporeal Life Support OrganizationAssociated with acute brain injuryMembrane oxygenation supportDisseminated intravascular coagulationRenal replacement therapyLife Support OrganizationClinical Validity of Serum Antibodies to SARS-CoV-2
Caturegli G, Materi J, Howard B, Caturegli P. Clinical Validity of Serum Antibodies to SARS-CoV-2. Annals Of Internal Medicine 2020, 173: m20-2889. PMID: 32628534, PMCID: PMC7370852, DOI: 10.7326/m20-2889.Peer-Reviewed Original ResearchConceptsNucleic acid amplification testsJohns Hopkins HospitalAntibodies to SARS-CoV-2SARS-CoV-2Follow-upEpstein-Barr virus capsid antigenSymptom onsetAcute respiratory distress syndromeAssociated with clinical severityRespiratory distress syndromeClinical immunology laboratoryControl groupVirus capsid antigenHealthy laboratory employeesEnzyme-linked immunosorbent assaySARS-CoV-2 IgG assaySARS-CoV-2 spike proteinClinical record reviewThyroperoxidase antibodiesCase patientsDistress syndromeCapsid antigenControl patientsSARS-CoV-2 antibodiesSevere acute respiratory syndrome coronavirus 2Trends in female surgeon authorship – The role of the middle author
Caturegli I, Caturegli G, Hays N, Laird C, Malik R, Rasko Y, Bafford A. Trends in female surgeon authorship – The role of the middle author. The American Journal Of Surgery 2020, 220: 1541-1548. PMID: 32409010, DOI: 10.1016/j.amjsurg.2020.04.025.Peer-Reviewed Original ResearchUnderstanding Characteristics of Acute Brain Injury in Adult Extracorporeal Membrane Oxygenation: An Autopsy Study.
Cho S, Geocadin R, Caturegli G, Chan V, White B, Dodd-O J, Kim B, Sussman M, Choi C, Whitman G, Chen L. Understanding Characteristics of Acute Brain Injury in Adult Extracorporeal Membrane Oxygenation: An Autopsy Study. Critical Care Medicine 2020, 48: e532-e536. PMID: 32102063, DOI: 10.1097/ccm.0000000000004289.Peer-Reviewed Original ResearchConceptsHypoxic-ischemic brain injuryExtracorporeal membrane oxygenationAcute brain injuryMembrane oxygenationIntracranial hemorrhageExtracorporeal membrane oxygenation nonsurvivorsExtracorporeal membrane oxygenation durationIschemic infarctionVenoarterial extracorporeal membrane oxygenationExtracorporeal membrane oxygenation cannulationExtracorporeal membrane oxygenation patientsRisk factorsCerebral cortexBrain injuryAssociated with acute brain injuryExtracorporeal membrane oxygenator support timeAdult extracorporeal membrane oxygenationOxygenation durationRenal impairmentHepatic impairmentTiming of acute brain injuryAntiplatelet useOxygenation patientsHemoglobin levelsIntracerebral hemorrhageModifiable Risk Factors and Mortality From Ischemic and Hemorrhagic Strokes in Patients Receiving Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Organization Registry.
Cho S, Canner J, Chiarini G, Calligy K, Caturegli G, Rycus P, Barbaro R, Tonna J, Lorusso R, Kilic A, Choi C, Ziai W, Geocadin R, Whitman G. Modifiable Risk Factors and Mortality From Ischemic and Hemorrhagic Strokes in Patients Receiving Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Organization Registry. Critical Care Medicine 2020, 48: e897-e905. PMID: 32931195, PMCID: PMC8170265, DOI: 10.1097/ccm.0000000000004498.Peer-Reviewed Original ResearchConceptsHemorrhagic strokeRisk factorsAssociated with hemorrhagic strokeModifiable risk factorsIschemic strokeAssociated with ischemic strokeVenoarterial extracorporeal membrane oxygenationBrain injuryExtracorporeal membrane oxygenationIn-hospital mortalityPromote preventionAcute brain injuryRenal replacement therapyMembrane oxygenationFemale sexSupport organizationsMortality rateReplacement therapyStrokeDays of extracorporeal membrane oxygenationExtracorporeal Life Support Organization registryExtracorporeal membrane oxygenation durationExtracorporeal membrane oxygenation supportExtracorporeal membrane oxygenation patientsVenoarterial extracorporeal membrane oxygenation support
2018
Extraordinary disease-free survival in a rare malignant extrarenal rhabdoid tumor: a case report and review of the literature
D’Amico F, Bertacco A, Cesari M, Mescoli C, Caturegli G, Gondolesi G, Cillo U. Extraordinary disease-free survival in a rare malignant extrarenal rhabdoid tumor: a case report and review of the literature. Journal Of Medical Case Reports 2018, 12: 39. PMID: 29452605, PMCID: PMC5816521, DOI: 10.1186/s13256-017-1554-2.Peer-Reviewed Original ResearchConceptsExtrarenal rhabdoid tumorMalignant extrarenal rhabdoid tumorRhabdoid tumorAggressive metastatic featuresDisease-free survivalPositive prognostic factorLong-term survivalAdjuvant chemotherapyNode involvementMetastatic nodesOrgan metastasisPrognostic factorsSurgical treatmentCase presentationWePoor outcomePoor prognosisCaucasian manCase reportGastrointestinal tractMetastatic featuresTumorsSurvivalLiterature reviewExtraordinary caseChemotherapy
2016
Use of Fluorescein Isothiocyanate-Inulin as a Marker for Intestinal Ischemic Injury
AlKukhun A, Caturegli G, Munoz-Abraham AS, Judeeba S, Patron-Lozano R, Morotti R, Rodriguez-Davalos MI, Geibel JP. Use of Fluorescein Isothiocyanate-Inulin as a Marker for Intestinal Ischemic Injury. Journal Of The American College Of Surgeons 2016, 224: 1066-1073. PMID: 28017811, DOI: 10.1016/j.jamcollsurg.2016.12.016.Peer-Reviewed Original ResearchConceptsFluorescein isothiocyanate-inulinIschemic injuryIntestinal ischemiaIntestinal transplantationFluid secretionIntestinal ischemic injuryIntestinal tissue samplesSmall intestine segmentsHEPES-Ringer solutionIntestinal graftMesenteric ischemiaIschemic intestineHistopathologic samplesExperimental armControl armControl intestineIschemic stateBlinded pathologistIschemiaIntestinal lumenIntestinal tissueIntestine segmentsScoring systemFluid shiftsInjuryTestosterone vs. aromatase inhibitor in older men with low testosterone: effects on cardiometabolic parameters
Dias J, Shardell M, Carlson O, Melvin D, Caturegli G, Ferrucci L, Chia C, Egan J, Basaria S. Testosterone vs. aromatase inhibitor in older men with low testosterone: effects on cardiometabolic parameters. Andrology 2016, 5: 31-40. PMID: 27792869, PMCID: PMC5794008, DOI: 10.1111/andr.12284.Peer-Reviewed Original ResearchConceptsC-reactive proteinTransdermal testosterone gelAromatase inhibitionTreatment armsOlder menEffects of long-term testosterone replacementTestosterone levelsLong-term testosterone replacementHomeostatic model assessment of insulin resistanceModel assessment of insulin resistanceMid-thigh fatResponse to OGTTAssessment of insulin resistanceFasting lipid levelsHomeostatic model assessmentLow testosterone levelsNon-diabetic menAbdominal subcutaneous fatLow T levelsSubcutaneous fatFasting lipidsDouble-blindPlacebo-controlledTestosterone gelCardiometabolic parameters
2014
Difference in Muscle Quality over the Adult Life Span and Biological Correlates in the Baltimore Longitudinal Study of Aging
Moore A, Caturegli G, Metter E, Makrogiannis S, Resnick S, Harris T, Ferrucci L. Difference in Muscle Quality over the Adult Life Span and Biological Correlates in the Baltimore Longitudinal Study of Aging. Journal Of The American Geriatrics Society 2014, 62: 230-236. PMID: 24438020, PMCID: PMC3945403, DOI: 10.1111/jgs.12653.Peer-Reviewed Original ResearchConceptsLongitudinal Study of AgingBaltimore Longitudinal Study of AgingStudy of AgingMuscle qualityBaltimore Longitudinal StudyThigh muscle cross-sectional areaMuscle cross-sectional areaMeasure of muscle qualityMeasures of adiposityAdult life courseDomains of cognitive functionIsokinetic dynamometryMuscle strengthFinger tapping speedAnthropometric measurementsMotor conduction velocityPeroneal nerve motor conduction velocityAdult life spanMuscle massMultivariate regression analysisLife courseConduction velocityMotor controlMuscle areaCognitive function
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