2023
Management of Anticoagulation Therapy in ECMO-Associated Ischemic Stroke and Intracranial Hemorrhage
Prokupets R, Kannapadi N, Chang H, Caturegli G, Bush E, Kim B, Keller S, Geocadin R, Whitman G, Cho S, Acton M, Rando H, Alejo D, Calligy K, Anderson S, Shou B, Sussman M, Wilcox C, Zhang L, Brown P, Peeler A. Management of Anticoagulation Therapy in ECMO-Associated Ischemic Stroke and Intracranial Hemorrhage. Innovations Technology And Techniques In Cardiothoracic And Vascular Surgery 2023, 18: 49-57. PMID: 36628944, PMCID: PMC10236353, DOI: 10.1177/15569845221141702.Peer-Reviewed Original ResearchMeSH KeywordsAnticoagulantsExtracorporeal Membrane OxygenationHumansIntracranial HemorrhagesIschemic StrokeRetrospective StudiesConceptsAcute ischemic strokeIntracranial hemorrhageVA-ECMOVV-ECMOAnticoagulation managementManagement of anticoagulant therapyAntithrombotic therapy managementICH expansionVA-ECMO patientsVenovenous (VVIschemic strokeResumption of anticoagulationExtracorporeal membrane oxygenationCohort of patientsTertiary care centerOptimal anticoagulation managementDiagnosis of acute ischemic strokeIn-hospital mortalityIntracranial hemorrhage survivorsAcute ischemic stroke survivorsAnticoagulation reversalECMO patientsAnticoagulant therapyThromboembolic eventsMembrane oxygenation
2022
Early Low Pulse Pressure in VA-ECMO Is Associated with Acute Brain Injury
Shou B, Wilcox C, Florissi I, Kalra A, Caturegli G, Zhang L, Bush E, Kim B, Keller S, Whitman G, Cho S. Early Low Pulse Pressure in VA-ECMO Is Associated with Acute Brain Injury. Neurocritical Care 2022, 38: 612-621. PMID: 36167950, PMCID: PMC10040467, DOI: 10.1007/s12028-022-01607-y.Peer-Reviewed Original ResearchConceptsAssociated with acute brain injuryAcute brain injuryLower pulse pressureHypoxic ischemic brain injuryVA-ECMOIschemic brain injuryPulse pressureIntracranial hemorrhageCerebral edemaVenoarterial extracorporeal membrane oxygenationECMO day 1VA-ECMO patientsIschemic strokeExtracorporeal membrane oxygenationRetrospective analysis of adultsBrain injuryMarkers of cardiovascular functionTertiary care centerPulse pressure <Multivariate logistic regressionBrain deathContinuous-flow mechanical circulatory supportMechanical circulatory supportAnalysis of adultsECMO support
2020
Acute Brain Injury in Infant Venoarterial Extracorporeal Membrane Oxygenation: An Autopsy Study.
Caturegli G, Cho S, White B, Chen L. Acute Brain Injury in Infant Venoarterial Extracorporeal Membrane Oxygenation: An Autopsy Study. Pediatric Critical Care Medicine 2020, 22: 297-302. PMID: 33055528, DOI: 10.1097/pcc.0000000000002573.Peer-Reviewed Original ResearchMeSH KeywordsAutopsyBrain InjuriesExtracorporeal Membrane OxygenationHumansInfantIntracranial HemorrhagesRetrospective StudiesConceptsExtracorporeal membrane oxygenationVenoarterial extracorporeal membrane oxygenationAcute brain injuryHypoxic-ischemic brain injuryMembrane oxygenationMedian ageIntracranial hemorrhageExtracorporeal membrane oxygenation support durationExtracorporeal membrane oxygenation durationExtracorporeal membrane oxygenation initiationExtracorporeal membrane oxygenation patientsBrain injuryElevated liver enzymesAssociated with acute brain injuryApgar scoreGestational ageOxygenation durationTiming of acute brain injuryHepatic impairmentAnticoagulant therapyPathology recordsBirth weightOxygenation patientsOxygenation initiationAutopsied patients
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