2023
Challenges in determining death by neurologic criteria in extracorporeal membrane oxygenation – A single center experience
Zhao D, Caturegli G, Wilcox C, Stephens R, Kim B, Keller S, Geocadin R, Suarez J, Whitman G, Cho S. Challenges in determining death by neurologic criteria in extracorporeal membrane oxygenation – A single center experience. Perfusion 2023, 39: 1238-1246. PMID: 37387124, PMCID: PMC10756925, DOI: 10.1177/02676591231187548.Peer-Reviewed Original ResearchConceptsExtracorporeal membrane oxygenation patientsExtracorporeal membrane oxygenationApnea testingWithdrawal of life-sustaining treatmentAncillary testsMembrane oxygenationSingle center experienceVV ECMO patientsTertiary care centerAbsent brainstem reflexesNeurological exam findingsLife-sustaining treatmentVV-ECMORetrospective reviewTertiary centerImaging findingsExam findingsBrainstem reflexesCenter's experienceNeurological examPatientsDiagnostic criteriaCare centerDetermination of DNCNeurologic criteriaCharacteristics of delirium and its association with sedation and in-hospital mortality in patients with COVID-19 on veno-venous extracorporeal membrane oxygenation
Sun P, Fanning J, Peeler A, Shou B, Lindsley J, Caturegli G, Whitman G, Cha S, Kim B, Cho S, investigators H. Characteristics of delirium and its association with sedation and in-hospital mortality in patients with COVID-19 on veno-venous extracorporeal membrane oxygenation. Frontiers In Medicine 2023, 10: 1172063. PMID: 37305142, PMCID: PMC10248255, DOI: 10.3389/fmed.2023.1172063.Peer-Reviewed Original ResearchAcute respiratory distress syndromeVeno-venous extracorporeal membrane oxygenationCOVID-19 acute respiratory distress syndromeIn-hospital mortalityVV-ECMOExtracorporeal membrane oxygenationRichmond Agitation-Sedation ScaleProportion of daysMembrane oxygenationLonger duration of deliriumNon-survivorsSevere COVID-19 acute respiratory distress syndromeCharacteristics of deliriumRespiratory distress syndromeDelirium daysAssociated with sedationAverage daily dosageMultivariate logistic regressionAssociated with mortalityDuration of deliriumConfusion Assessment MethodECMO durationECMO daysDistress syndromeAdult patientsManagement of Anticoagulation Therapy in ECMO-Associated Ischemic Stroke and Intracranial Hemorrhage
Prokupets R, Kannapadi N, Chang H, Caturegli G, Bush E, Kim B, Keller S, Geocadin R, Whitman G, Cho S, Acton M, Rando H, Alejo D, Calligy K, Anderson S, Shou B, Sussman M, Wilcox C, Zhang L, Brown P, Peeler A. Management of Anticoagulation Therapy in ECMO-Associated Ischemic Stroke and Intracranial Hemorrhage. Innovations Technology And Techniques In Cardiothoracic And Vascular Surgery 2023, 18: 49-57. PMID: 36628944, PMCID: PMC10236353, DOI: 10.1177/15569845221141702.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeIntracranial hemorrhageVA-ECMOVV-ECMOAnticoagulation managementManagement of anticoagulant therapyAntithrombotic therapy managementICH expansionVA-ECMO patientsVenovenous (VVIschemic strokeResumption of anticoagulationExtracorporeal membrane oxygenationCohort of patientsTertiary care centerOptimal anticoagulation managementDiagnosis of acute ischemic strokeIn-hospital mortalityIntracranial hemorrhage survivorsAcute ischemic stroke survivorsAnticoagulation reversalECMO patientsAnticoagulant therapyThromboembolic eventsMembrane oxygenation
2022
Characterization of Cerebral Hemodynamics with TCD in Patients Undergoing VA-ECMO and VV-ECMO: a Prospective Observational Study
Caturegli G, Zhang L, Mayasi Y, Gusdon A, Ergin B, Ponomarev V, Kim B, Keller S, Geocadin R, Whitman G, Cho S, Ziai W. Characterization of Cerebral Hemodynamics with TCD in Patients Undergoing VA-ECMO and VV-ECMO: a Prospective Observational Study. Neurocritical Care 2022, 38: 407-413. PMID: 36510107, PMCID: PMC9744662, DOI: 10.1007/s12028-022-01653-6.Peer-Reviewed Original ResearchConceptsVA-ECMOVV-ECMOIntraparenchymal hemorrhageTCD studiesAssociated with intraparenchymal hemorrhageComposite bleeding eventsCerebral hemodynamicsVA-ECMO patientsSingle-center cohortTCD-mean flow velocityBackgroundExtracorporeal membrane oxygenationVV ECMO patientsTertiary care centerProspective observational studyProspective cohort studyInternal carotid arteryAcute brain injuryVenovenous ECMOECMO populationBleeding eventsECMO modeMembrane oxygenationMulticenter studyVenoarterial ECMOPulsatility indexTranscranial Doppler microemboli and acute brain injury in extracorporeal membrane oxygenation: A prospective observational study
Caturegli G, Kapoor S, Ponomarev V, Kim B, Whitman G, Ziai W, Cho S, Investigators H, Zhang L, Mayasi Y, Gusdon A, Ergin B, Keller S, Acton M, Rando H, Alejo D, Calligy K, Anderson S, Shou B, Mendez-Tellez P, Chang H, Sussman M, Wilcox C, Brown P, Peeler A. Transcranial Doppler microemboli and acute brain injury in extracorporeal membrane oxygenation: A prospective observational study. JTCVS Techniques 2022, 15: 111-122. PMID: 36276670, PMCID: PMC9579875, DOI: 10.1016/j.xjtc.2022.07.026.Peer-Reviewed Original ResearchExtracorporeal membrane oxygenationAcute brain injuryIntra-aortic balloon pumpTranscranial Doppler examinationVA-ECMOVV-ECMOMicroembolic signalsAssociated with presenceTranscranial DopplerMembrane oxygenationBalloon pumpLong-term neurologic follow-upVentricular assist deviceVA extracorporeal membrane oxygenationECMO parametersExtracorporeal membrane oxygenation circuitMultivariate logistic regression analysisVenovenous (VVArterial thromboembolic eventsCohort of patientsTertiary care centerNeurological follow-upMicroembolic signal monitoringProspective observational studyProspective cohort study
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