2025
Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Ethical, Regulatory, and Socioeconomic Dimensions of Theranostic Digital Twins
Strigari L, Schwarz J, Bradshaw T, Brosch-Lenz J, Currie G, El-Fakhri G, Jha A, MeĹľinska S, Pandit-Taskar N, Roncali E, Shi K, Uribe C, Yusufaly T, Zaidi H, Rahmim A, Saboury B. Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Ethical, Regulatory, and Socioeconomic Dimensions of Theranostic Digital Twins. Journal Of Nuclear Medicine 2025, 66: jnumed.124.268186. PMID: 39848769, PMCID: PMC12051771, DOI: 10.2967/jnumed.124.268186.Peer-Reviewed Original ResearchRadiopharmaceutical therapyNuclear oncologySociety of Nuclear MedicinePredictive dosimetryDosimetric informationTreatment planningTreatment outcomesLack of reimbursementTreatment personalizationDose responseTreatment optimizationEtiological mechanismsRobust security measuresPatient consentReal-world systemsNuclear medicineCross-border data sharingPatientsTreatmentEthical approval
2018
Subject-specific brain tumor growth modelling via an efficient Bayesian inference framework
Chang Y, Sharp G, Li Q, Shih H, El Fakhri G, Ra J, Woo J. Subject-specific brain tumor growth modelling via an efficient Bayesian inference framework. Proceedings Of SPIE--the International Society For Optical Engineering 2018, 10574: 105742i. PMID: 30050231, PMCID: PMC6056378, DOI: 10.1117/12.2293145.Peer-Reviewed Original ResearchTumor growthOptimal treatmentExternal beam radiotherapyBrain tumor progressionBeam radiotherapyBrain tumor growthTumor growth modelTumor infiltrationTumor parametersTumor progressionEffective therapyClinical dataTherapy planningTumorIndividualized therapyTherapyTumor boundariesProliferation rateRadiotherapyNon-invasiveState-of-the-art methodsTreatmentState-of-the-artChemotherapy
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