2025
Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Current Tools, Techniques, and Uncharted Territories
Yusufaly T, Roncali E, Brosch-Lenz J, Uribe C, Jha A, Currie G, Dutta J, El-Fakhri G, McMeekin H, Pandit-Taskar N, Schwartz J, Shi K, Strigari L, Zaidi H, Saboury B, Rahmim A. Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Current Tools, Techniques, and Uncharted Territories. Journal Of Nuclear Medicine 2025, 66: 509-515. PMID: 39947910, PMCID: PMC11960611, DOI: 10.2967/jnumed.124.267927.Peer-Reviewed Original ResearchRadiopharmaceutical therapyImage-based dosimetryPrediction of doseInternal dosimetryPersonalized treatment plansMetastatic diseaseDosimetryNuclear oncologyClinical outcomesNuclear medicineClinical endpointsTreatment planningOncology communityDose responseEtiological mechanismsTargeted deliveryRadiobiologyRadiotherapyMalignancyRadiationLong-termTherapyPharmacotherapyDoseRadiopharmacokinetics
2015
Monitoring proton therapy with PET
Paganetti H, Fakhri G. Monitoring proton therapy with PET. British Journal Of Radiology 2015, 88: 20150173. PMID: 25989699, PMCID: PMC4628541, DOI: 10.1259/bjr.20150173.Peer-Reviewed Original ResearchConceptsPatient set-upDose conformityDose shapingInterfractional changesProton beamBeam deliveryDose calculationProton therapyTumor coveragePhotonic techniquesTreatment volumeTotal energyPatient anatomyBeamRadiation therapyProtonPatientsTherapyReduced total energyDoseSet-upRangeCalculationsRadiationEnergy
2014
Preliminary Investigation of CBCT Imaging Optimization for Image-Guided Radiation Therapy
Bian J, Sharp G, Park Y, Bortfeld T, Fakhri G. Preliminary Investigation of CBCT Imaging Optimization for Image-Guided Radiation Therapy. 2014, 1-4. DOI: 10.1109/nssmic.2014.7430871.Peer-Reviewed Original ResearchImage-guided radiation therapyCone-beam CTCone-beam CT image qualityImprove CBCT image qualityCBCT image qualityCone-beam CT imagesOptimization-based reconstruction algorithmsReduce patient doseImage qualityCBCT dataImages of improved qualityImaging doseReconstruction algorithmIterative reconstruction techniqueASD-POCSImage reconstruction algorithmPatient doseImprove image qualityRadiation therapyDose reductionRadiation doseImage-guidedDosePoor image qualityExposure levels
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