2024
Progression of Femoral Osteolytic Metastases after Intramedullary Nailing and Subsequent Salvage Techniques
Jiang W, Latich I, Lindskog D, Friedlaender G, Lee F. Progression of Femoral Osteolytic Metastases after Intramedullary Nailing and Subsequent Salvage Techniques. Cancers 2024, 16: 2812. PMID: 39199585, PMCID: PMC11352437, DOI: 10.3390/cancers16162812.Peer-Reviewed Original ResearchPre-existing lesionsOsteolytic metastasesIntramedullary nailingCancer progressionTwo-week postoperative follow-upFollow-upSalvage techniqueFunction scoresRadiation-resistant tumorsPoor surgical candidacyPostoperative follow-upNail failureTransport of cancer cellsPostoperative radiationSurgical salvageCombined painSingle-institutionSurgical outcomesIntramedullary nail insertionPathological fracturesRetrospective studySurgical candidacyAdult patientsPercutaneous salvageOsteolytic lesions
2023
Bone Mass Changes Following Percutaneous Radiofrequency Ablation, Osteoplasty, Reinforcement, and Internal Fixation of Periacetabular Osteolytic Metastases
Jiang W, Caruana D, Dussik C, Conway D, Latich I, Chapiro J, Lindskog D, Friedlaender G, Lee F. Bone Mass Changes Following Percutaneous Radiofrequency Ablation, Osteoplasty, Reinforcement, and Internal Fixation of Periacetabular Osteolytic Metastases. Journal Of Clinical Medicine 2023, 12: 4613. PMID: 37510728, PMCID: PMC10380351, DOI: 10.3390/jcm12144613.Peer-Reviewed Original ResearchPercutaneous radiofrequency ablationBone mass changesCT scanMedian survivalHounsfield unitsOsteolytic metastasesRadiofrequency ablationBone massCancer-induced bone lossSuperior median survivalAvailable CT scansThree-dimensional volumetric analysisInternal screw fixationPeriacetabular areaPercutaneous stabilizationBone lossInternal fixationSingle institutionOrthopedic interventionsScrew fixationPatientsMonthsVolumetric analysisSurvivalScansComparison of Percutaneous Interventional Ablation-Osteoplasty-Reinforcement-Internal Fixation (AORIF), Long Intramedullary Nailing, and Hemiarthroplasty for the Treatment of Focal Metastatic Osteolytic Lesions in the Femoral Head and Neck
Jiang W, Friedlaender G, Lindskog D, Latich I, Lee F. Comparison of Percutaneous Interventional Ablation-Osteoplasty-Reinforcement-Internal Fixation (AORIF), Long Intramedullary Nailing, and Hemiarthroplasty for the Treatment of Focal Metastatic Osteolytic Lesions in the Femoral Head and Neck. CardioVascular And Interventional Radiology 2023, 46: 649-657. PMID: 37052716, DOI: 10.1007/s00270-023-03425-x.Peer-Reviewed Original ResearchConceptsOsteolytic lesionsFemoral headSurgical complicationsRevision proceduresLong intramedullary nailingResultsSixty-seven patientsPost-operative complicationsEffective alternative treatmentTraditional surgical approachesAmbulatory scoreCombined painPrimary outcomeMedical complicationsMetastatic lesionsOncologic careRetrospective studyIntramedullary nailingSurgical approachFunction scoresNeck lesionsEarly improvementIM groupHemiarthroplastyComparative efficacyAlternative treatmentPercutaneous Ablation, Osteoplasty, Reinforcement, and Internal Fixation for Pain and Ambulatory Function in Periacetabular Osteolytic Malignancies.
Dussik C, Toombs C, Alder K, Yu K, Berson E, Ibe I, Li F, Lindskog D, Friedlaender G, Latich I, Lee F. Percutaneous Ablation, Osteoplasty, Reinforcement, and Internal Fixation for Pain and Ambulatory Function in Periacetabular Osteolytic Malignancies. Radiology 2023, 307: e221401. PMID: 36916888, DOI: 10.1148/radiol.221401.Peer-Reviewed Original ResearchConceptsOsteolytic neoplasmAmbulatory functionInternal fixationEastern Cooperative Oncology Group scoreIndex scoreConversion hip arthroplastyRetrospective observational studySurgical site infectionKaplan-Meier analysisLong-term painQuality of lifeLong-term improvementWilcoxon signed-rank testNonambulatory patientsSecondary outcomesPrimary outcomeSite infectionOncologic careECOG scorePercutaneous ablationPeriacetabular metastasisProtrusio acetabuliFunctional improvementSigned-rank testClinical data
2020
Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus.
Samuel AM, Munger AM, Lee FY, Friedlaender GE, Ibe IK, Lindskog DM. Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus. Orthopedics 2020, 43: e498-e502. PMID: 32882054, DOI: 10.3928/01477447-20200827-05.Peer-Reviewed Original ResearchConceptsRadionuclide bone scanBone scanMRI scansPositive findingsNegative findingsMagnetic resonance imaging (MRI) scansBone scan findingsProgression of lesionsResonance imaging scansDiagnosis of enchondromaAcademic medical centerBivariate logistic regressionAssociation of boneScan findingsAggressive featuresRadiographic findingsEndosteal scallopingBenign enchondromaImaging scansMedical recordsMedical CenterMalignant lesionsCartilaginous lesionsEnchondromaPatientsMinimally Invasive Image-Guided Ablation, Osteoplasty, Reinforcement, and Internal Fixation (AORIF) for Osteolytic Lesions in the Pelvis and Periarticular Regions of Weight-Bearing Bones
Lee FY, Latich I, Toombs C, Mungur A, Conway D, Alder K, Ibe I, Lindskog D, Friedlaender G. Minimally Invasive Image-Guided Ablation, Osteoplasty, Reinforcement, and Internal Fixation (AORIF) for Osteolytic Lesions in the Pelvis and Periarticular Regions of Weight-Bearing Bones. Journal Of Vascular And Interventional Radiology 2020, 31: 649-658.e1. PMID: 32139256, DOI: 10.1016/j.jvir.2019.11.029.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesAdultAgedAged, 80 and overBone CementsBone NeoplasmsBone RemodelingBone ScrewsCalcaneusCementoplastyFemaleFemoral NeoplasmsFemurFracture Fixation, InternalHumansMaleMiddle AgedOsteolysisPelvic BonesPostoperative ComplicationsProspective StudiesRecovery of FunctionTibiaTime FactorsTreatment OutcomeWeight-BearingConceptsOsteolytic lesionsInternal fixationVisual analog scale pain scoreMusculoskeletal Tumor Society scoreProspective clinical cohort studyFunctional ambulation scoreOsteolytic skeletal lesionsPainful osteolytic lesionsScale pain scoresClinical cohort studyInvasive percutaneous approachWeight-bearing boneInternal fixation screwsBalloon osteoplastyPain scoresCohort studyProphylactic stabilizationSevere painSociety ScoreConsecutive patientsSurgical treatmentEarly outcomesTreatment optionsPercutaneous approachFunctional improvement
2018
Immuno-oncologic Approach to Musculoskeletal Tumors
Ibe I, Sahlstrom A, Nguyen M, Lindskog D, Friedlaender G, Lee F. Immuno-oncologic Approach to Musculoskeletal Tumors. Techniques In Orthopaedics 2018, 33: 140-147. DOI: 10.1097/bto.0000000000000305.Peer-Reviewed Original ResearchImmune systemImmuno-oncologic therapiesSoft tissue sarcomasHost immune surveillanceActive immune responseTreatment of boneImmune therapyTumor burdenTissue sarcomasTreatment of cancerTreatment optionsMusculoskeletal tumorsComprehensive careImproved outcomesImmune surveillanceImmune responseOrthopedic oncologyMalignant cellsImmunotherapyCancer cellsPrecision medicineDistant sitesPatientsUnderlying mechanismTherapy
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