2015
Multimodality therapy for locally advanced thymomas: A propensity score–matched cohort study from the European Society of Thoracic Surgeons Database
Leuzzi G, Rocco G, Ruffini E, Sperduti I, Detterbeck F, Weder W, Venuta F, Van Raemdonck D, Thomas P, Facciolo F, Group E. Multimodality therapy for locally advanced thymomas: A propensity score–matched cohort study from the European Society of Thoracic Surgeons Database. Journal Of Thoracic And Cardiovascular Surgery 2015, 151: 47-57.e1. PMID: 26403869, DOI: 10.1016/j.jtcvs.2015.08.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAsiaChemotherapy, AdjuvantChildChi-Square DistributionDatabases, FactualDisease ProgressionDisease-Free SurvivalEuropeFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisNeoadjuvant TherapyNeoplasm Recurrence, LocalNeoplasm StagingNorth AmericaPropensity ScoreProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesRisk AssessmentRisk FactorsSocieties, MedicalThymectomyThymomaThymus NeoplasmsTime FactorsTreatment OutcomeTumor BurdenYoung AdultConceptsRelapse-free survivalAdvanced thymomaMultimodality therapyOverall survivalT classificationPropensity score-matched cohort studyMultivariate Cox proportional hazards modelPropensity score-matched analysisCox proportional hazards modelPathologic T classificationStage III thymomaThoracic Surgeons databaseSignificant survival advantageSpecific pathologic featuresStrong predictive factorProportional hazards modelInduction therapyAdjuvant therapyPT3 tumorsCohort studyIndependent predictorsPrognostic impactMultivariable analysisPathologic featuresPredictive factors
2014
Outcome of primary neuroendocrine tumors of the thymus: A joint analysis of the International Thymic Malignancy Interest Group and the European Society of Thoracic Surgeons databases
Filosso PL, Yao X, Ahmad U, Zhan Y, Huang J, Ruffini E, Travis W, Lucchi M, Rimner A, Antonicelli A, Guerrera F, Detterbeck F, Committee E. Outcome of primary neuroendocrine tumors of the thymus: A joint analysis of the International Thymic Malignancy Interest Group and the European Society of Thoracic Surgeons databases. Journal Of Thoracic And Cardiovascular Surgery 2014, 149: 103-109.e2. PMID: 25308116, DOI: 10.1016/j.jtcvs.2014.08.061.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overChemotherapy, AdjuvantDatabases, FactualFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisNeoadjuvant TherapyNeoplasm GradingNeoplasm Recurrence, LocalNeoplasm StagingNeuroendocrine TumorsProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesRisk FactorsThymectomyThymus NeoplasmsTime FactorsTreatment OutcomeYoung AdultConceptsInternational Thymic Malignancy Interest GroupMasaoka-Koga stageOverall survivalCompleteness of resectionPrimary neuroendocrine tumorThoracic Surgeons databasePrognostic factorsHistologic subtypeSurgeons databaseNeuroendocrine tumorsHigher biologic aggressivenessMasaoka-Koga stage ICommon histologic subtypeMedian overall survivalEuropean SocietyRetrospective multicenter studyKaplan-Meier methodStrong prognostic factorLog-rank testInduction therapyAdjuvant treatmentCumulative incidenceResection statusComplete resectionMulticenter study
2010
A Systematic Review of Restaging After Induction Therapy for Stage IIIa Lung Cancer: Prediction of Pathologic Stage
de Cabanyes Candela S, Detterbeck FC. A Systematic Review of Restaging After Induction Therapy for Stage IIIa Lung Cancer: Prediction of Pathologic Stage. Journal Of Thoracic Oncology 2010, 5: 389-398. PMID: 20186025, DOI: 10.1097/jto.0b013e3181ce3e5e.Peer-Reviewed Original ResearchConceptsInduction therapyPositron emission tomographyLung cancerComputed tomographySystematic reviewStage IIIA lung cancerEmission tomographyIIIA lung cancerMediastinal node involvementRepeat mediastinoscopyNode involvementComplete responsePathologic findingsEsophageal ultrasoundPathologic stageNeedle aspirationExpert handsRestagingFalse negative rateMediastinoscopyTherapyFN rateTomographyPatientsSurgery
2004
Seeking a Home for a PET, Part 3 Emerging Applications of Positron Emission Tomography Imaging in the Management of Patients With Lung Cancer
Detterbeck FC, Vansteenkiste JF, Morris DE, Dooms CA, Khandani AH, Socinski MA. Seeking a Home for a PET, Part 3 Emerging Applications of Positron Emission Tomography Imaging in the Management of Patients With Lung Cancer. CHEST Journal 2004, 126: 1656-1666. PMID: 15539740, DOI: 10.1378/chest.126.5.1656.Peer-Reviewed Original ResearchConceptsManagement of patientsLung cancerPET imagingCycles of chemotherapyCompletion of treatmentPossible lung cancerIntensity of uptakePositron emission tomography (PET) imagingEmission Tomography ImagingPositron emission tomographyFurther technologic improvementsInduction therapyPatient outcomesBiological aggressivenessPatientsEmission tomographyTechnologic improvementsTomography imagingStaging approachRadiotherapy treatment fieldCancerTreatment fieldImagingTreatmentPET images
2003
Gemcitabine-Based Combinations as Preoperative Therapy in Resectable Non–Small-Cell Lung Cancer
Socinski MA, Rivera MP, Detterbeck FC. Gemcitabine-Based Combinations as Preoperative Therapy in Resectable Non–Small-Cell Lung Cancer. Clinical Lung Cancer 2003, 4: s50-s55. PMID: 14720337, DOI: 10.3816/clc.2003.s.004.Peer-Reviewed Original ResearchGemcitabine-containing regimensPhase III trialsStage III NSCLCComplete surgical resectionPreoperative therapyIII trialsSurgical resectionInduction therapyLung cancerResectable non-small cell lung cancerNon-small cell lung cancerDominant recurrence patternGemcitabine-based combinationsSystemic micrometastatic diseaseCisplatin/gemcitabinePhase II trialMajority of patientsMinority of patientsCell lung cancerOverall response rateStandard of careAdjuvant chemotherapyAdvanced NSCLCII trialStage IB