2024
Xylazine induces dopamine release and augments the effects of fentanyl
Trinko J, Foscue E, Kong E, Basu A, Corstens A, Thompson S, Kaye A, Taylor J, DiLeone R. Xylazine induces dopamine release and augments the effects of fentanyl. Journal Of Clinical Investigation 2024, 134: e183354. PMID: 39545408, PMCID: PMC11563672, DOI: 10.1172/jci183354.Peer-Reviewed Original Research
2023
Ketogenic diet enhances the effects of oxycodone in mice
Trinko R, Diaz D, Foscue E, Thompson S, Taylor J, DiLeone R. Ketogenic diet enhances the effects of oxycodone in mice. Scientific Reports 2023, 13: 7507. PMID: 37160959, PMCID: PMC10170077, DOI: 10.1038/s41598-023-33458-8.Peer-Reviewed Original ResearchConceptsOpioid use disorderKetogenic dietKD miceUse disordersTreatment of OUDEffects of KDEffects of oxycodoneClinical pain managementAlcohol use disorderProgressive ratio scheduleSex-specific effectsChronic oxycodoneLess oxycodoneOpioid withdrawalAntinociceptive effectPain managementPrescription opioidsSide effectsOxycodoneLocomotor activityTherapeutic potentialOpioidsDietary effectsOpiate sensitivityMice
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply